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Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Weichen Huang

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

Cognitive impairment detection through spontaneous speech is a promising avenue for early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI), where timely intervention can significantly improve patient outcomes. The…

Sound · Computer Science 2025-02-19 Yifan Gao , Long Guo , Hong Liu

Alzheimer's disease (AD) is associated with local (e.g. brain tissue atrophy) and global brain changes (loss of cerebral connectivity), which can be detected by high-resolution structural magnetic resonance imaging. Conventionally, these…

Machine Learning · Computer Science 2021-05-11 Sarah C. Brüningk , Felix Hensel , Catherine R. Jutzeler , Bastian Rieck

Objective: This paper presents an Alzheimer's disease (AD) detection method based on learning structural similarity between Magnetic Resonance Images (MRIs) and representing this similarity as a graph. Methods: We construct the similarity…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Kuo Yang , Emad A. Mohammed , Behrouz H. Far

Early diagnosis of Alzheimer Diagnostics (AD) is a challenging task due to its subtle and complex clinical symptoms. Deep learning-assisted medical diagnosis using image recognition techniques has become an important research topic in this…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Yihao Lin , Ximeng Li , Yan Zhang , Jinshan Tang

Dementia is a neurological syndrome marked by cognitive decline. Alzheimer's disease (AD) and Frontotemporal dementia (FTD) are the common forms of dementia, each with distinct progression patterns. EEG, a non-invasive tool for recording…

Signal Processing · Electrical Eng. & Systems 2024-08-21 Shivani Ranjan , Ayush Tripathi , Harshal Shende , Robin Badal , Amit Kumar , Pramod Yadav , Deepak Joshi , Lalan Kumar

Cognitive decline often surfaces in language years before diagnosis. It is frequently non-experts, such as those closest to the patient, who first sense a change and raise concern. As LLMs become integrated into daily communication and used…

Computation and Language · Computer Science 2025-05-20 Lotem Peled-Cohen , Maya Zadok , Nitay Calderon , Hila Gonen , Roi Reichart

Recent advancements in large language models (LLMs) have achieved promising performances across various applications. Nonetheless, the ongoing challenge of integrating long-tail knowledge continues to impede the seamless adoption of LLMs in…

Computation and Language · Computer Science 2024-10-21 Dawei Li , Shu Yang , Zhen Tan , Jae Young Baik , Sukwon Yun , Joseph Lee , Aaron Chacko , Bojian Hou , Duy Duong-Tran , Ying Ding , Huan Liu , Li Shen , Tianlong Chen

Dementia is a syndrome, generally of a chronic nature characterized by a deterioration in cognitive function, especially in the geriatric population and is severe enough to impact their daily activities. Early diagnosis of dementia is…

Audio and Speech Processing · Electrical Eng. & Systems 2020-07-21 Rupayan Chakraborty , Meghna Pandharipande , Chitralekha Bhat , Sunil Kumar Kopparapu

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Alzheimer's disease is one of the most common types of neurodegenerative disease, characterized by the accumulation of amyloid-beta plaque and tau tangles. Recently, deep learning approaches have shown promise in Alzheimer's disease…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Gia Minh Hoang , Youngjoo Lee , Jae Gwan Kim

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. Despite the many advantages of joint modeling, the standard forms suffer from limitations that arise…

Machine Learning · Statistics 2018-07-10 Bryan Lim , Mihaela van der Schaar

Frontotemporal dementia and Alzheimer's disease are two common forms of dementia and are easily misdiagnosed as each other due to their similar pattern of clinical symptoms. Differentiating between the two dementia types is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Da Ma , Donghuan Lu , Karteek Popuri , Mirza Faisal Beg

Neurological disorders that affect speech production, such as Alzheimer's Disease (AD), significantly impact the lives of both patients and caregivers, whether through social, psycho-emotional effects or other aspects not yet fully…

The detection of Alzheimer's disease (AD) from spontaneous speech has attracted increasing attention while the sparsity of training data remains an important issue. This paper handles the issue by knowledge transfer, specifically from both…

Computation and Language · Computer Science 2024-04-02 Ziyun Cui , Wen Wu , Wei-Qiang Zhang , Ji Wu , Chao Zhang

The retina provides a unique, noninvasive window into Alzheimer's disease (AD) and dementia, capturing early structural changes through morphometric features, while systemic and lifestyle risk factors reflect well-established contributors…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Seowung Leem , Lin Gu , Chenyu You , Kuang Gong , Ruogu Fang

Introduction: Machine learning (ML) has been extremely successful in identifying key features from high-dimensional datasets and executing complicated tasks with human expert levels of accuracy or greater. Methods: We summarize and…

Alzheimer's disease is a neurodegenerative disorder marked by progressive declines in memory and language that reduce independence in daily life, motivating socially assistive robotic support. This paper presents MEMOR-E, a mobile quadruped…

Artificial Intelligence · Computer Science 2026-05-26 Maissa Abir Smaili , Eren Sadikoglu , Ransalu Senanayake

INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…