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Molecular docking is a critical process for drug discovery and challenging due to the complexity and size of biomolecular systems, where the optimal binding configuration of a drug to a target protein is determined. Hybrid classical-quantum…

Emerging Technologies · Computer Science 2025-03-07 Christos Papalitsas , Yanfei Guan , Shreyas Waghe , Athanasios Liakos , Ioannis Balatsos , Vassilios Pantazopoulos

This paper proposes a hybrid quantum-classical algorithm to solve a fundamental power system problem called unit commitment (UC). The UC problem is decomposed into a quadratic subproblem, a quadratic unconstrained binary optimization (QUBO)…

Quantum Physics · Physics 2022-04-19 Reza Mahroo , Amin Kargarian

In recent years, quantum computing has drawn significant interest within the field of high-energy physics. We explore the potential of quantum algorithms to resolve the combinatorial problems in particle physics experiments. As a concrete…

High Energy Physics - Phenomenology · Physics 2024-11-12 Jacob L. Scott , Zhongtian Dong , Taejoon Kim , Kyoungchul Kong , Myeonghun Park

Hybrid quantum-classical algorithms such as the quantum approximate optimization algorithm (QAOA) are considered one of the most promising approaches for leveraging near-term quantum computers for practical applications. Such algorithms are…

Quantum Physics · Physics 2022-06-16 Ruslan Shaydulin , Ilya Safro , Jeffrey Larson

The Quantum Approximate Optimization Algorithm (QAOA), which is a variational quantum algorithm, aims to give sub-optimal solutions of combinatorial optimization problems. It is widely believed that QAOA has the potential to demonstrate…

The Quantum Approximate Optimization Algorithm (QAOA) is suggested as a promising application on early quantum computers. Here, a quantum-inspired classical algorithm, the mean-field Approximate Optimization Algorithm (mean-field AOA), is…

The quantum approximate optimization algorithm (QAOA) is a hybrid variational quantum-classical algorithm that solves combinatorial optimization problems. While there is evidence suggesting that the fixed form of the standard QAOA ansatz is…

Combinatorial problems are a common challenge in business, requiring finding optimal solutions under specified constraints. While significant progress has been made with variational approaches such as QAOA, most problems addressed are…

Quantum Physics · Physics 2025-01-14 Monit Sharma , Yan Jin , Hoong Chuin Lau , Rudy Raymond

This research explores the integration of the Quantum Approximate Optimization Algorithm (QAOA) into Hybrid Quantum-HPC systems for solving the Max-Cut problem, comparing its performance with classical algorithms like brute-force search and…

Quantum Physics · Physics 2024-10-22 Ishan Patwardhan , Akhil Akkapelli

The unit commitment (UC) problem stands as a critical optimization challenge in the electrical power industry. It is classified as NP-hard, placing it among the most intractable problems to solve. This paper introduces a novel hybrid…

Quantum Physics · Physics 2024-12-17 Bruna Salgado , André Sequeira , Luis Paulo Santos

We present a hybrid classical-quantum algorithm to solve optimization problems in current quantum computers, whose basic idea is to assist variational quantum eigensolvers (VQE) with adiabatic change of the Hamiltonian. The rational for…

Quantum Physics · Physics 2018-06-07 A. Garcia-Saez , J. I. Latorre

We propose a hybrid quantum-classical approximate optimization algorithm for photonic quantum computing, specifically tailored for addressing continuous-variable optimization problems. Inspired by counterdiabatic protocols, our algorithm…

Quantum Physics · Physics 2024-10-03 Pranav Chandarana , Koushik Paul , Mikel Garcia-de-Andoin , Yue Ban , Mikel Sanz , Xi Chen

Recent results by Harrow et. al. and by Ta-Shma, suggest that quantum computers may have an exponential advantage in solving a wealth of linear algebraic problems, over classical algorithms. Building on the quantum intuition of these…

Quantum Physics · Physics 2017-04-07 Michael Ben-Or , Lior Eldar

The Bin Packing Problem (BPP) stands out as a paradigmatic combinatorial optimization problem in logistics. Quantum and hybrid quantum-classical algorithms are expected to show an advantage over their classical counterparts in obtaining…

We present an approach, which we term quantum-enhanced optimization, to accelerate classical optimization algorithms by leveraging quantum sampling. Our method uses quantum-generated samples as warm starts to classical heuristics for…

Quantum Physics · Physics 2025-08-25 Ieva Čepaitė , Niam Vaishnav , Leo Zhou , Ashley Montanaro

Combining quantum computers with classical compute power has become a standard means for developing algorithms that are eventually supposed to beat any purely classical alternatives. While in-principle advantages for solution quality or…

Quantum Physics · Physics 2026-01-23 Simon Thelen , Wolfgang Mauerer

Feedback-based quantum algorithms have recently emerged as potential methods for approximating the ground states of Hamiltonians. One such algorithm, the feedback-based algorithm for quantum optimization (FALQON), is specifically designed…

Quantum Physics · Physics 2025-08-18 Salahuddin Abdul Rahman , Özkan Karabacak , Rafal Wisniewski

We apply digitized Quantum Annealing (QA) and Quantum Approximate Optimization Algorithm (QAOA) to a paradigmatic task of supervised learning in artificial neural networks: the optimization of synaptic weights for the binary perceptron. At…

Quantum Physics · Physics 2021-12-21 Pietro Torta , Glen B. Mbeng , Carlo Baldassi , Riccardo Zecchina , Giuseppe E. Santoro

We describe a quantum algorithm that solves combinatorial optimization problems by quantum simulation of a classical simulated annealing process. Our algorithm exploits quantum walks and the quantum Zeno effect induced by evolution…

Quantum Physics · Physics 2009-02-02 R. D. Somma , S. Boixo , H. Barnum , E. Knill

Hybrid quantum-classical algorithms such as the Quantum Approximate Optimization Algorithm (QAOA) are considered as one of the most encouraging approaches for taking advantage of near-term quantum computers in practical applications. Such…