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Functional magnetic resonance imaging (fMRI) is essential for developing encoding models that identify functional changes in language-related brain areas of individuals with Neurocognitive Disorders (NCD). While large language model…

Neurons and Cognition · Quantitative Biology 2024-07-16 Yuejiao Wang , Xianmin Gong , Lingwei Meng , Xixin Wu , Helen Meng

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique that records neural activations in the brain by capturing the blood oxygen level in different regions based on the task performed by a subject. Given fMRI data, the…

Computer Vision and Pattern Recognition · Computer Science 2021-09-21 Ashish Jaiswal , Ashwin Ramesh Babu , Mohammad Zaki Zadeh , Fillia Makedon , Glenn Wylie

The aging society urgently requires scalable methods to monitor cognitive decline and identify social and psychological factors indicative of dementia risk in older adults. Our machine learning (ML) models captured facial, acoustic,…

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

Computation and Language · Computer Science 2021-02-25 Swati Padhee , Anurag Illendula , Megan Sadler , Valerie L. Shalin , Tanvi Banerjee , Krishnaprasad Thirunarayan , William L. Romine

Over the past decade, studies of naturalistic language processing where participants are scanned while listening to continuous text have flourished. Using word embeddings at first, then large language models, researchers have created…

Computation and Language · Computer Science 2024-11-05 Laurent Bonnasse-Gahot , Christophe Pallier

Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…

Signal Processing · Electrical Eng. & Systems 2022-11-17 Yasunori Yamada , Masatomo Kobayashi , Kaoru Shinkawa , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

Memory disorders are a central factor in the decline of functioning and daily activities in elderly individuals. The confirmation of the illness, initiation of medication to slow its progression, and the commencement of occupational therapy…

Sound · Computer Science 2024-02-08 Marko Niemelä , Mikaela von Bonsdorff , Sami Äyrämö , Tommi Kärkkäinen

MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Simon Joseph Clément Crête , Marta Kersten-Oertel , Yiming Xiao

Early dementia diagnosis requires biomarkers sensitive to both structural and functional brain changes. While structural neuroimaging biomarkers have progressed significantly, objective functional biomarkers of early cognitive decline…

Neurons and Cognition · Quantitative Biology 2025-04-16 Tomasz M. Rutkowski , Stanisław Narębski , Mihoko Otake-Matsuura , Tomasz Komendziński

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Accurate identification of brain function is necessary to understand the neurobiology of cognitive ageing, and thereby promote well-being across the lifespan. A common tool used to investigate neurocognitive ageing is functional magnetic…

Neurons and Cognition · Quantitative Biology 2020-05-21 Kamen A. Tsvetanov , Richard N. A. Henson , James B. Rowe

Major depressive disorder (MDD) is one of the most common mental health conditions that has been intensively investigated for its association with brain atrophy and mortality. Recent studies reveal that the deviation between the predicted…

Neurons and Cognition · Quantitative Biology 2022-10-18 Yunsong Luo , Wenyu Chen , Jiang Qiu , Tao Jia

Advances in neuroimaging techniques have provided us novel insights into understanding how the human mind works. Functional magnetic resonance imaging (fMRI) is the most popular and widely used neuroimaging technique, and there is growing…

Neurons and Cognition · Quantitative Biology 2022-06-15 Jihyun Hur , Jaeyeong Yang , Hoyoung Doh , Woo-Young Ahn

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Quantitative Methods · Quantitative Biology 2020-10-07 Sema Candemir , Xuan V. Nguyen , Luciano M. Prevedello , Matthew T. Bigelow , Richard D. White , Barbaros S. Erdal

Functional magnetic resonance imaging (fMRI) is one of the most popular methods for studying the human brain. Task-related fMRI data processing aims to determine which brain areas are activated when a specific task is performed and is…

Signal Processing · Electrical Eng. & Systems 2022-10-18 Paris A. Karakasis , Athanasios P. Liavas , Nicholas D. Sidiropoulos , Panagiotis G. Simos , Efrosini Papadaki

Functional Magnetic Resonance Imaging (fMRI) provides dynamical access into the complex functioning of the human brain, detailing the hemodynamic activity of thousands of voxels during hundreds of sequential time points. One approach…

Neurons and Cognition · Quantitative Biology 2008-01-16 Francois G. Meyer , Greg J. Stephens

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

Neurons and Cognition · Quantitative Biology 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu

Functional Magnetic Resonance Imaging (fMRI) is a non-invasive technique for studying brain activity. During an fMRI session, the subject executes a set of tasks (task-related fMRI study) or no tasks (resting-state fMRI), and a sequence of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Christos Theodoropoulos , Christos Chatzichristos , Sabine Van Huffel

Understanding how the brain represents the multifaceted properties of words in context is essential for explaining the neural architecture of human language. Here, we combine large-scale psycholinguistic modeling with naturalistic fMRI to…

Neurons and Cognition · Quantitative Biology 2026-01-21 Xuan Yang , Chuanji Gao , Cheng Xiao , Nicholas Riccardi , Rutvik H. Desai

Patients with Frontotemporal Dementia (FTD) have impaired cognitive abilities, executive and behavioral traits, loss of language ability, and decreased memory capabilities. Based on the distinct patterns of cortical atrophy and symptoms,…

Artificial Intelligence · Computer Science 2021-04-13 Km Poonam , Rajlakshmi Guha , Partha P Chakrabarti
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