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Data scarcity remains a central challenge in materials discovery, where finding meaningful descriptors and tuning models for generalization is critical but inherently a discrete optimization problem prone to multiple local minima…

With the development of quantum computing, the use of quantum algorithms to solve combinatorial optimization problems on quantum computers has become a major research focus. The Quadratic Unconstrained Binary Optimization (QUBO) model…

Computational Engineering, Finance, and Science · Computer Science 2025-04-10 Haoqian Pan , Changhong Lu

Advances in artificial intelligence (AI) and deep learning have raised concerns about its increasing energy consumption, while demand for deploying AI in mobile devices and machines at the edge is growing. Binary neural networks (BNNs) have…

Optimization and Control · Mathematics 2026-01-05 Jonas Christoffer Villumsen , Yusuke Sugita

The bin packing is a well-known NP-Hard problem in the domain of artificial intelligence, posing significant challenges in finding efficient solutions. Conversely, recent advancements in quantum technologies have shown promising potential…

Quantum Physics · Physics 2024-01-17 Lorenzo Cellini , Antonio Macaluso , Michele Lombardi

Quadratic Unconstrained Binary Optimization models are useful for solving a diverse range of optimization problems. Constraints can be added by incorporating quadratic penalty terms into the objective, often with the introduction of slack…

Optimization and Control · Mathematics 2021-05-18 Amit Verma , Mark Lewis

Quadratic unconstrained binary optimization (QUBO) problems are well-studied, not least because they can be approached using contemporary quantum annealing or classical hardware acceleration. However, due to limited precision and hardware…

Quantum Physics · Physics 2023-07-06 Sascha Mücke , Thore Gerlach , Nico Piatkowski

Black-box optimization minimizes an objective function without derivatives or explicit forms. Such an optimization method with continuous variables has been successful in the fields of machine learning and material science. For discrete…

Gaussian Processes are used in many applications to model spatial phenomena. Within this context, a key issue is to decide the set of locations where to take measurements so as to obtain a better approximation of the underlying function.…

Emerging Technologies · Computer Science 2019-01-31 Lorenzo Bottarelli , Alessandro Farinelli

Advancements in Quantum Computing (QC) and Neural Combinatorial Optimization (NCO) represent promising steps in tackling complex computational challenges. On the one hand, Variational Quantum Algorithms such as QAOA can be used to solve a…

Quantum Physics · Physics 2024-05-14 Georg Kruse , Rodrigo Coehlo , Andreas Rosskopf , Robert Wille , Jeanette Miriam Lorenz

Combinatorial optimization problems play a central role in computer science with many real world applications. A number of relevant problems remain computationally difficult to solve as they lie in the NP-hard complexity class. We present a…

Quantum Physics · Physics 2026-05-11 Kapil Goswami , Peter Schmelcher

We investigate a framework for binary image denoising via restricted Boltzmann machines (RBMs) that introduces a denoising objective in quadratic unconstrained binary optimization (QUBO) form and is well-suited for quantum annealing. The…

Quantum Physics · Physics 2023-08-21 Phillip Kerger , Ryoji Miyazaki

Hypergraph partitioning is a fundamental optimization problem with applications in data management and other domains involving higher-order relations. In this paper, we study balanced hypergraph partitioning from the perspective of quantum…

Social and Information Networks · Computer Science 2026-05-05 Yiran Li , Y. Batuhan Yilmaz , Michael Silver , Zachary Vernec , Hans-Arno Jacobsen

Combinatorial optimization is anticipated to be one of the primary use cases for quantum computation in the coming years. The Quantum Approximate Optimization Algorithm (QAOA) and Quantum Annealing (QA) can potentially demonstrate…

Mission planning often involves optimising the use of ISR (Intelligence, Surveillance and Reconnaissance) assets in order to achieve a set of mission objectives within allowed parameters subject to constraints. The missions of interest…

Quantum Physics · Physics 2024-09-30 Ethan Davies , Pranav Kalidindi

Quantum computing has emerged as a promising alternative for solving combinatorial optimization problems. The standard approach for encoding optimization problems on quantum processing units (QPUs) involves transforming them into their…

Emerging Technologies · Computer Science 2025-10-15 Meerzhan Kanatbekova , Vincenzo De Maio , Ivona Brandic

Here, we present two complementary approaches that advance quadratic unconstrained binary optimization (QUBO) toward practical use in data-driven materials design and other real-valued black-box optimization tasks. First, we introduce a…

Materials Science · Physics 2025-12-15 Thomas Plehn , Daniel Barragan-Yani , Eric Breitbarth , Guillermo Requena , David Melching

The Quantum Approximate Optimization Algorithm (QAOA) has shown promise in solving combinatorial optimization problems by leveraging quantum computational power. We propose a simple approach, the Two-Step QAOA, which aims to improve the…

Quantum Physics · Physics 2025-02-25 Yuichiro Minato

This paper presents key enhancements to our previous work~\cite{naghmouchi2024mixed} on a hybrid Benders decomposition (HBD) framework for solving mixed integer linear programs (MILPs). In our approach, the master problem is reformulated as…

Quantum Physics · Physics 2026-01-23 Anna Joliot , M. Yassine Naghmouchi , Wesley Coelho

A book about turning high-degree optimization problems into quadratic optimization problems that maintain the same global minimum (ground state). This book explores quadratizations for pseudo-Boolean optimization, perturbative gadgets used…

Quantum Physics · Physics 2019-09-24 Nike Dattani

Quantum optimization is the most mature quantum computing technology to date, providing a promising approach towards efficiently solving complex combinatorial problems. Methods such as adiabatic quantum computing (AQC) have been employed in…

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