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Machine learning has the potential to accelerate materials discovery by accurately predicting materials properties at a low computational cost. However, the model inputs remain a key stumbling block. Current methods typically use…

Computational Physics · Physics 2021-01-07 Rhys E. A. Goodall , Alpha A. Lee

Accurately predicting experimentally realizable 3D molecular crystal structures from their 2D chemical graphs is a long-standing open challenge in computational chemistry called crystal structure prediction (CSP). Efficiently solving this…

Reliable and robust methods of predicting the crystal structure of a compound, based only on its chemical composition, is crucial to the study of materials and their applications. Despite considerable ongoing research efforts, crystal…

Materials Science · Physics 2017-07-26 Qi-Jun Hong , Joseph Yasi , Axel van de Walle

Generative models trained on internet-scale data are capable of generating novel and realistic texts, images, and videos. A natural next question is whether these models can advance science, for example by generating novel stable materials.…

Machine Learning · Computer Science 2024-06-05 Sherry Yang , KwangHwan Cho , Amil Merchant , Pieter Abbeel , Dale Schuurmans , Igor Mordatch , Ekin Dogus Cubuk

Crystalline materials are widely used in technological applications, yet their discovery remains a significant challenge. As their properties are driven by structure, crystal structure prediction (CSP) methods play a central role in…

Machine Learning · Computer Science 2026-04-28 Stavros Gerolymatos , J. Kyle Brubaker , Martin J. A. Schuetz , Vladimir V. Gusev

Crystal structure prediction is a fundamental problem in materials science. We present CrystalFormer-CSP, an efficient framework that unifies data-driven heuristic and physics-driven optimization approaches to predict stable crystal…

Materials Science · Physics 2025-12-23 Zhendong Cao , Shigang Ou , Lei Wang

The key challenge in advancing multivalent-ion batteries lies in finding suitable intercalation hosts. Open-tunnel oxides, featuring one-dimensional channels or nanopores, show promise for enabling effective ion transport. However, the vast…

Materials Science · Physics 2024-10-10 Joy Datta , Dibakar Datta , Amruth Nadimpally , Nikhil Koratkar

Generative machine learning (ML) models hold great promise for accelerating materials discovery through the inverse design of inorganic crystals, enabling an unprecedented exploration of chemical space. Yet, the lack of standardized…

Crystal structure determination from powder diffraction patterns is a complex challenge in materials science, often requiring extensive expertise and computational resources. This study introduces DiffractGPT, a generative pre-trained…

Materials Science · Physics 2025-08-13 Kamal Choudhary

We develop and test new machine learning strategies for accelerating molecular crystal structure ranking and crystal property prediction using tools from geometric deep learning on molecular graphs. Leveraging developments in graph-based…

Materials Science · Physics 2024-07-29 Michael Kilgour , Jutta Rogal , Mark Tuckerman

Generative AI models, such as score-based diffusion models, have recently advanced the field of computational materials science by enabling the generation of new materials with desired properties. In addition, these models could also be…

Materials Science · Physics 2026-01-06 Timo Reents , Arianna Cantarella , Marnik Bercx , Pietro Bonfà , Giovanni Pizzi

The traditional techniques for extracting polycrystalline grain structures from microscopy images, such as transmission electron microscopy (TEM) and scanning electron microscopy (SEM), are labour-intensive, subjective, and time-consuming,…

Machine Learning · Computer Science 2025-04-22 Ahmed Sobhi Saleh , Kristof Croes , Hajdin Ceric , Ingrid De Wolf , Houman Zahedmanesh

We study property prediction for crystal materials. A crystal structure consists of a minimal unit cell that is repeated infinitely in 3D space. How to accurately represent such repetitive structures in machine learning models remains…

Chemical Physics · Physics 2023-11-08 Yuchao Lin , Keqiang Yan , Youzhi Luo , Yi Liu , Xiaoning Qian , Shuiwang Ji

Crystal structure optimization is fundamental to materials modeling but remains computationally expensive when performed with density-functional theory (DFT). Machine-learning (ML) approaches offer substantial acceleration, yet existing…

Materials Science · Physics 2026-03-26 Ziduo Yang , Wei Zhuo , Huiqiang Xie , Xiaoqing Liu , Lei Shen

The application of generative models in crystal structure prediction (CSP) has gained significant attention. Conditional generation--particularly the generation of crystal structures with specified stability or other physical properties has…

Materials Science · Physics 2026-01-14 Takanori Ishii , Kaoru Hisama , Kohei Shinohara

Generative models show great promise for the inverse design of molecules and inorganic crystals, but remain largely ineffective within more complex structures such as amorphous materials. Here, we present a diffusion model that reliably…

Disordered Systems and Neural Networks · Physics 2026-01-21 Kai Yang , Daniel Schwalbe-Koda

Application of artificial intelligence (AI) has been ubiquitous in the growth of research in the areas of basic sciences. Frequent use of machine learning (ML) and deep learning (DL) based methodologies by researchers has resulted in…

Materials Science · Physics 2024-09-10 Shrimon Mukherjee , Madhusudan Ghosh , Partha Basuchowdhuri

Determining the stability of chemical compounds is essential for advancing material discovery. In this study, we introduce a novel deep neural network model designed to predict a crystal's formation energy, which identifies its stability…

Materials Science · Physics 2026-04-21 V. Torlao , E. A. Fajardo

In recent years, the realm of crystalline materials has witnessed a surge in the development of generative models, predominantly aimed at the inverse design of crystals with tailored physical properties. However, spatial symmetry, which…

Computational Physics · Physics 2024-10-31 Baoning Wang , Zhiyuan Xu , Zhiyu Han , Qiwen Nie , Hang Xiao , Gang Yan

Obtaining 3D conformations of realistic polyatomic molecules at the quantum chemistry level remains challenging, and although recent machine learning advances offer promise, predicting large-molecule structures still requires substantial…

Chemical Physics · Physics 2025-11-18 Yifei Zhu , Jiahui Zhang , Jiawei Peng , Mengge Li , Chao Xu , Zhenggang Lan
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