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Related papers: Identifiability in epidemic models with prior immu…

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Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

Populations and Evolution · Quantitative Biology 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu

Mathematical models are routinely applied to interpret biological data, with common goals that include both prediction and parameter estimation. A challenge in mathematical biology, in particular, is that models are often complex and…

Methodology · Statistics 2025-11-18 Alexander P Browning , Jennifer A Flegg , Ryan J Murphy

Identifiability concerns finding which unknown parameters of a model can be quantified from given input-output data. Many linear ODE models, used in systems biology and pharmacokinetics, are unidentifiable, which means that parameters can…

Algebraic Geometry · Mathematics 2013-12-12 Nicolette Meshkat , Seth Sullivant

Identifying highly susceptible individuals in spreading processes is of great significance in controlling outbreaks. In this paper, we explore the susceptibility of people in susceptible-infectious-recovered (SIR) and rumor spreading…

Physics and Society · Physics 2015-05-20 Shaoting Tang , Xian Teng , Sen Pei , Shu Yan , Zhiming Zheng

Mathematical models of epidemics often use compartmental models dividing the population into several compartments. Based on a microscopic setting describing the temporal evolution of the subpopulation sizes in the compartments by stochastic…

Populations and Evolution · Quantitative Biology 2025-03-11 Florent Ouabo Kamkumo , Ibrahim Mbouandi Njiasse , Ralf Wunderlich

A network epidemic model is studied. The underlying social network has two different types of group structures, households and workplaces, such that each individual belongs to exactly one household and one workplace. The random network is…

Probability · Mathematics 2024-10-10 Frank Ball , Tom Britton , Peter Neal

This paper studies the problems of identifiability and estimation in high-dimensional nonparametric latent structure models. We introduce an identifiability theorem that generalizes existing conditions, establishing a unified framework…

Statistics Theory · Mathematics 2025-08-06 Yichen Lyu , Pengkun Yang

We adapt the article of Forien, Pang, Pardoux and Zotsa: Arxiv preprint Arxiv2210.04667(2022), on epidemic models with varying infectivity and waning immunity, to incorporate the memory of the last infection. To this end, we introduce a…

Probability · Mathematics 2025-05-02 Hélène Guérin , Arsene Brice Zotsa-Ngoufack

This contribution presents a parameter identification methodology for the accurate and fast estimation of model parameters in a pseudo-two-dimensional (P2D) battery model. The methodology consists of three key elements. First, the data for…

Systems and Control · Electrical Eng. & Systems 2025-07-21 L. D. Couto , K. Haghverdi , F. Guo , K. Trad , G. Mulder

Latent class models have wide applications in social and biological sciences. In many applications, pre-specified restrictions are imposed on the parameter space of latent class models, through a design matrix, to reflect practitioners'…

Statistics Theory · Mathematics 2019-06-03 Yuqi Gu , Gongjun Xu

In designed experiments and surveys, known laws or design feat ures provide checks on the most relevant aspects of a model and identify the target parameters. In contrast, in most observational studies in the health and social sciences, the…

Methodology · Statistics 2010-01-18 Sander Greenland

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic…

Populations and Evolution · Quantitative Biology 2020-11-06 Hernán De Battista , José García-Clúa , Sebastián Nuñez , Fernando Inthamoussou , Fabricio Garelli

Principal stratification is a general framework for studying causal mechanisms involving post-treatment variables. When estimating principal causal effects, the principal ignorability assumption is commonly invoked, which we study in detail…

Methodology · Statistics 2026-04-21 Minxuan Wu , Joseph Antonelli

Time varying susceptibility of host at individual level due to waning and boosting immunity is known to induce rich long-term behavior of disease transmission dynamics. Meanwhile, the impact of the time varying heterogeneity of host…

Populations and Evolution · Quantitative Biology 2018-08-28 Yukihiko Nakata , Ryosuke Omori

Recently, we proposed an state model (compartment model) to describe the progression of a chronic disease with an pre-clinical (undiagnosed) state before clinical diagnosis. It is an open question, if a sequence of cross-sectional studies…

Populations and Evolution · Quantitative Biology 2015-11-24 Ralph Brinks

We consider an epidemiological SIR model and a positive threshold $M$. Using a parametric expression for the solution curve of the SIR model and the Lambert W function, we establish necessary and sufficient conditions on the basic…

Optimization and Control · Mathematics 2021-07-09 Andrés David Báez-Sánchez , Nara Bobko

The paper describes and compares three approaches to modeling an epidemic spread. The first approach is a well-known system of SIR ordinary differential equations. The second is a mean-field model, in which an isolation strategy for each…

Populations and Evolution · Quantitative Biology 2024-11-06 Viktoriya Petrakova , Olga Krivorotko

We prove identifiability of parameters for a broad class of random graph mixture models. These models are characterized by a partition of the set of graph nodes into latent (unobservable) groups. The connectivities between nodes are…

Statistics Theory · Mathematics 2010-06-07 Elizabeth S. Allman , Catherine Matias , John A. Rhodes

An ultrametric model of epidemic spread of infections based on the classical SIR model is proposed. Ultrametrics on a set of individuals based on theire hierarchical clustering relativly to the average time of infectious contact is…

Physics and Society · Physics 2020-07-21 V. T. Volov , A. P. Zubarev

Missing data problems arise in many applied research studies. They may jeopardize statistical inference of the model of interest, if the missing mechanism is nonignorable, that is, the missing mechanism depends on the missing values…

Statistics Theory · Mathematics 2015-09-15 Wang Miao , Peng Ding , Zhi Geng