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Weakly supervised semantic segmentation (WSSS) in histopathology seeks to reduce annotation cost by learning from image-level labels, yet it remains limited by inter-class homogeneity, intra-class heterogeneity, and the region-shrinkage…

Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Zijie Fang , Yifeng Wang , Ye Zhang , Zhi Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Weakly supervised semantic segmentation is a challenging task as it only takes image-level information as supervision for training but produces pixel-level predictions for testing. To address such a challenging task, most recent…

Computer Vision and Pattern Recognition · Computer Science 2019-11-20 Bingfeng Zhang , Jimin Xiao , Yunchao Wei , Mingjie Sun , Kaizhu Huang

Scribble annotations significantly reduce the cost and labor required for dense labeling in large medical datasets with complex anatomical structures. However, current scribble-supervised learning methods are limited in their ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Luyi Qiu , Tristan Till , Xiaobao Guo , Adams Wai-Kin Kong

Image-level weakly-supervised semantic segmentation (WSSS) reduces the usually vast data annotation cost by surrogate segmentation masks during training. The typical approach involves training an image classification network using global…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Arvi Jonnarth , Yushan Zhang , Michael Felsberg

Medical image segmentation is essential in diagnostics, treatment planning, and healthcare, with deep learning offering promising advancements. Notably, the convolutional neural network (CNN) excels in capturing local image features,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Chao Ma , Ziyang Wang

Semi-supervised learning (SSL) has emerged as an effective paradigm for medical image segmentation, reducing the reliance on extensive expert annotations. Meanwhile, vision-language models (VLMs) have demonstrated strong generalization and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Jiaqi Guo , Mingzhen Li , Hanyu Su , Santiago López , Lexiaozi Fan , Daniel Kim , Aggelos Katsaggelos

Pixel-wise segmentation is one of the most data and annotation hungry tasks in our field. Providing representative and accurate annotations is often mission-critical especially for challenging medical applications. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Simon Reiß , Constantin Seibold , Alexander Freytag , Erik Rodner , Rainer Stiefelhagen

Weakly supervised semantic segmentation offers a label-efficient solution to train segmentation models for volumetric medical imaging. However, existing approaches often rely on 2D encoders that neglect the inherent volumetric nature of the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Yiheng Lyu , Lian Xu , Mohammed Bennamoun , Farid Boussaid , Coen Arrow , Girish Dwivedi

Brain lesion segmentation remains challenging due to small, low-contrast lesions, anisotropic sampling, and cross-slice discontinuities. We propose CenterMamba-SAM, an end-to-end framework that freezes a pretrained backbone and trains only…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yu Tian , Zhongheng Yang , Chenshi Liu , Yiyun Su , Ziwei Hong , Zexi Gong , Jingyuan Xu

The application of deep learning to medical image segmentation has been hampered due to the lack of abundant pixel-level annotated data. Few-shot Semantic Segmentation (FSS) is a promising strategy for breaking the deadlock. However, a…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Xiaoang Shen , Guokai Zhang , Huilin Lai , Jihao Luo , Jianwei Lu , Ye Luo

Recently, Mamba-based methods have become popular in medical image segmentation due to their lightweight design and long-range dependency modeling capabilities. However, current segmentation methods frequently encounter challenges in fetal…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Caixu Xu , Junming Wei , Huizhen Chen , Pengchen Liang , Bocheng Liang , Ying Tan , Xintong Wei

Whole-slide images (WSIs) are an important data modality in computational pathology, yet their gigapixel resolution and lack of fine-grained annotations challenge conventional deep learning models. Multiple instance learning (MIL) offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Qian Zeng , Yihui Wang , Shu Yang , Yingxue Xu , Fengtao Zhou , Jiabo Ma , Dejia Cai , Zhengyu Zhang , Lijuan Qu , Yu Wang , Li Liang , Hao Chen

Multi-modal medical image synthesis is pivotal for alleviating clinical data scarcity, yet existing methods fail to reconcile global anatomical consistency with high-fidelity local detail. We propose FermatSyn, which addresses three…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Feng Yuan

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Medical image segmentation typically demands extensive dense annotations for model training, which is both time-consuming and skill-intensive. To mitigate this burden, exemplar-based medical image segmentation methods have been introduced…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Qing En , Yuhong Guo

Accurate training labels are a key component for multi-class medical image segmentation. Their annotation is costly and time-consuming because it requires domain expertise. This work aims to develop a dual-branch network and automatically…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Jianfei Liu , Christopher Parnell , Ronald M. Summers

In the field of healthcare, precise skin lesion segmentation is crucial for the early detection and accurate diagnosis of skin diseases. Despite significant advances in deep learning for image processing, existing methods have yet to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Siyu Wang , Hua Wang , Huiyu Li , Fan Zhang

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

The success of deep learning methods in medical image segmentation tasks heavily depends on a large amount of labeled data to supervise the training. On the other hand, the annotation of biomedical images requires domain knowledge and can…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Xinrong Hu , Dewen Zeng , Xiaowei Xu , Yiyu Shi