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In the context of self-assembly, where complex structures can be assembled from smaller units, it is desirable to devise strategies towards disassembly and reassembly processes that reuse the constituent parts. A non-reciprocal multifarious…

Soft Condensed Matter · Physics 2025-09-30 Jakob Metson , Saeed Osat , Ramin Golestanian

Self-assembly materials are traditionally designed so that molecular or meso-scale components form a single kind of large structure. Here, we propose a scheme to create "multifarious assembly mixtures", which self-assemble many different…

Disordered Systems and Neural Networks · Physics 2015-06-22 Arvind Murugan , Zorana Zeravcic , Michael P. Brenner , Stanislas Leibler

In the self-assembly process which drives the formation of cellular membranes, micelles, and capsids, a collection of separated subunits spontaneously binds together to form functional and more ordered structures. In this work, we study the…

Biological Physics · Physics 2021-05-04 Mobolaji Williams

Self-assembly is a ubiquitous process in synthetic and biological systems, broadly defined as the spontaneous organization of multiple subunits (e.g. macromolecules, particles) into ordered multi-unit structures. The vast majority of…

Soft Condensed Matter · Physics 2023-08-08 Michael F. Hagan , Gregory M. Grason

We use analytic theory and computer simulation to study patterns formed during the growth of two-component assemblies in 2D and 3D. We show that these patterns undergo a nonequilibrium phase transition, at a particular growth rate, between…

Statistical Mechanics · Physics 2014-05-12 Stephen Whitelam , Lester O. Hedges , Jeremy D. Schmit

We present a quantitative measure of physical complexity, based on the amount of information required to build a given physical structure through self-assembly. Our procedure can be adapted to any given geometry, and thus to any given type…

Statistical Mechanics · Physics 2010-09-02 S. E. Ahnert , I. G. Johnston , T. M. A. Fink , J. P. K. Doye , A. A. Louis

In this paper we generalize a methodology [T. E. Ouldridge, A. A. Louis, and J. P. K. Doye, J. Phys.: Condens. Matter {\bf 22}, 104102 (2010)] for dealing with the inference of bulk properties from small simulations of self-assembling…

Soft Condensed Matter · Physics 2015-07-13 Thomas E. Ouldridge

Self-assembly in natural and synthetic molecular systems can create complex aggregates or materials whose properties and functionality rises from their internal structure and molecular arrangement. The key microscopic features that control…

Soft Condensed Matter · Physics 2021-09-03 Alberto Scacchi , Maria Sammalkorpi , Tapio Ala-Nissila

Both biological and artificial self-assembly processes can take place by a range of different schemes, from the successive addition of identical building blocks, to hierarchical sequences of intermediates, all the way to the fully…

Soft Condensed Matter · Physics 2015-08-12 Jim Madge , Mark A. Miller

Although tissues are usually studied in isolation, this situation rarely occurs in biology, as cells, tissues, and organs, coexist and interact across scales to determine both shape and function. Here, we take a quantitative approach…

Tissues and Organs · Quantitative Biology 2023-02-07 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

Spontaneous self-assembly in molecular systems is a fundamental route to both biological and engineered soft matter. Simple micellisation, emulsion formation, and polymer mixing principles are well understood. However, the principles behind…

Soft Condensed Matter · Physics 2021-09-21 Alberto Scacchi , Sousa Javan Nikkhah , Maria Sammalkorpi , Tapio Ala-Nissila

We investigate the self-assembly (crystallisation) of particles with hard cores and isotropic, square-well interactions, using a Monte Carlo scheme to simulate overdamped Langevin dynamics. We measure correlation and response functions…

Soft Condensed Matter · Physics 2015-03-19 Daphne Klotsa , Robert L. Jack

We describe some of the important physical characteristics of the `pathways', i.e. dynamical processes, by which molecular, nanoscale and micron-scale self-assembly occurs. We highlight the fact that there exist features of self-assembly…

Statistical Mechanics · Physics 2016-03-22 Stephen Whitelam , Robert L. Jack

Self-assembly, the process by which interacting components form well-defined and often intricate structures, is typically thought of as a spontaneous process arising from equilibrium dynamics. When a system is driven by external…

Statistical Mechanics · Physics 2021-11-12 Shriram Chennakesavalu , Grant M. Rotskoff

We use computer simulations to study a model, first proposed by Wales [1], for the reversible and monodisperse self-assembly of simple icosahedral virus capsid structures. The success and efficiency of assembly as a function of…

Biomolecules · Quantitative Biology 2010-02-24 Iain G. Johnston , Ard A. Louis , Jonathan P. K. Doye

Theories of phase change and self-assembly often invoke the idea of a `quasiequilibrium', a regime in which the nonequilibrium association of building blocks results nonetheless in a structure whose properties are determined solely by an…

Statistical Mechanics · Physics 2013-07-22 Stephen Whitelam , Rebecca Schulman , Lester Hedges

In conventional molecular simulation, metastable structures often survive over considerable computational time, resulting in difficulties in simulating equilibrium states. In order to overcome this difficulty, here we propose a newly…

Computational Physics · Physics 2011-10-21 Yuki Norizoe , Toshihiro Kawakatsu

We consider the self-assembly of composite structures from a group of nanocomponents, each consisting of particles within an $N$-atom system. Self-assembly pathways and rates for nanocomposites are derived via a multiscale analysis of the…

Biological Physics · Physics 2014-01-06 Stephen Pankavich , Peter Ortoleva

Understanding how highly symmetric, robust, monodisperse protein cages self-assemble can have major applications in various areas of bio-nanotechnology, such as drug delivery, biomedical imaging and gene therapy. We develop a model to…

Soft Condensed Matter · Physics 2018-09-11 Sanaz Panahandeh , Siyu Li , Roya Zandi

We study theoretically in the present work the self-assembly of molecules in an open system, which is fed by monomers and depleted in partial or complete clusters. Such a scenario is likely to occur for example in the context of viral…

Biological Physics · Physics 2014-02-18 Martin Castelnovo , Timothée Verdier , Lionel Foret
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