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Multimodal information processing has become increasingly important for enhancing image classification performance. However, the intricate and implicit dependencies across different modalities often hinder conventional methods from…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Yang Qiao , Xiaoyu Zhong , Xiaofeng Gu , Zhiguo Yu

Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Mingcheng Qu , Guang Yang , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Accurate and early detection of breast cancer is essential for successful treatment. This paper introduces a novel deep-learning approach for improved breast cancer classification in histopathological images, a crucial step in diagnosis.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Mahdie Ahmadi , Nader Karimi , Shadrokh Samavi

AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes.…

Automatic breast lesion detection and classification is an important task in computer-aided diagnosis, in which breast ultrasound (BUS) imaging is a common and frequently used screening tool. Recently, a number of deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2022-10-13 Zong Fan , Ping Gong , Shanshan Tang , Christine U. Lee , Xiaohui Zhang , Pengfei Song , Shigao Chen , Hua Li

The Cancer Genome Atlas (TCGA) has enabled novel discoveries and served as a large-scale reference dataset in cancer through its harmonized genomics, clinical, and imaging data. Numerous prior studies have developed bespoke deep learning…

Machine Learning · Computer Science 2026-05-11 Steven Song , Morgan Borjigin-Wang , Irene Madejski , Robert L. Grossman

Predicting the sensitivity of cancer cell lines to PLX-4720, a preclinical BRAF inhibitor, requires models capable of capturing the multilayered regulation of oncogenic signaling. Single-omics predictors are often insufficient because drug…

Multi-modal magnetic resonance (MR) imaging provides great potential for diagnosing and analyzing brain gliomas. In clinical scenarios, common MR sequences such as T1, T2 and FLAIR can be obtained simultaneously in a single scanning…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ziqi Huang , Li Lin , Pujin Cheng , Linkai Peng , Xiaoying Tang

Purpose: As visual inspection is an inherent process during radiological screening, the associated eye gaze data can provide valuable insights into relevant clinical decisions. As deep learning has become the state-of-the-art for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Zirui Qiu , Hassan Rivaz , Yiming Xiao

Cancer genomes exhibit a large number of different alterations that affect many genes in a diverse manner. It is widely believed that these alterations follow combinatorial patterns that have a strong connection with the underlying…

Machine Learning · Computer Science 2016-01-26 Jack P. Hou , Amin Emad , Gregory J. Puleo , Jian Ma , Olgica Milenkovic

OncoVision is a multimodal AI pipeline that combines mammography images and clinical data for better breast cancer diagnosis. Employing an attention-based encoder-decoder backbone, it jointly segments four ROIs - masses, calcifications,…

Attention-based learning for fine-grained image recognition remains a challenging task, where most of the existing methods treat each object part in isolation, while neglecting the correlations among them. In addition, the multi-stage or…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Ming Sun , Yuchen Yuan , Feng Zhou , Errui Ding

Integrating multi-omics data, such as DNA methylation, mRNA expression, and microRNA (miRNA) expression, offers a comprehensive view of the biological mechanisms underlying disease. However, the high dimensionality of multi-omics data, the…

Machine Learning · Computer Science 2026-02-12 Tiantian Yang , Zhiqian Chen

Medical images exhibit latent anatomical groupings, such as organs, tissues, and pathological regions, that standard Vision Transformers (ViTs) fail to exploit. While recent work like SBM-Transformer attempts to incorporate such structures…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Huimin Cheng , Xiaowei Yu , Shushan Wu , Luyang Fang , Chao Cao , Jing Zhang , Tianming Liu , Dajiang Zhu , Wenxuan Zhong , Ping Ma

Different aspects of a clinical sample can be revealed by multiple types of omics data. Integrated analysis of multi-omics data provides a comprehensive view of patients, which has the potential to facilitate more accurate clinical decision…

Machine Learning · Computer Science 2020-02-11 Xiaoyu Zhang , Jingqing Zhang , Kai Sun , Xian Yang , Chengliang Dai , Yike Guo

Background and objective Early diagnosis of gastric diseases is crucial to prevent fatal outcomes. Although histopathologic examination remains the diagnostic gold standard, it is performed entirely manually, making evaluations…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Mustafa Yurdakul , Sakir Tasdemir

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Accurate cancer survival prediction is crucial for assisting clinical doctors in formulating treatment plans. Multimodal data, including histopathological images and genomic data, offer complementary and comprehensive information that can…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Hui Luo , Jiashuang Huang , Hengrong Ju , Tianyi Zhou , Weiping Ding

Multimodal positron emission tomography-computed tomography (PET-CT) is used routinely in the assessment of cancer. PET-CT combines the high sensitivity for tumor detection with PET and anatomical information from CT. Tumor segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Xiaohang Fu , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

Multimodal learning, integrating histology images and genomics, promises to enhance precision oncology with comprehensive views at microscopic and molecular levels. However, existing methods may not sufficiently model the shared or…

Computer Vision and Pattern Recognition · Computer Science 2024-06-12 Huahui Yi , Xiaofei Wang , Kang Li , Chao Li