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We describe our contribution as industrial stakeholders to the existing open-source GPU4PySCF project (https: //github.com/pyscf/gpu4pyscf), a GPU-accelerated Python quantum chemistry package. We have integrated GPU acceleration into other…

PySCF is a general-purpose electronic structure platform designed from the ground up to emphasize code simplicity, both to aid new method development, as well as for flexibility in computational workflow. The package provides a wide range…

Over the past decade, the Python-based Simulations of Chemistry Framework (PySCF) has developed into a widely used open-source platform for electronic structure theory and quantum chemical method development. This article reviews the major…

Chemical Physics · Physics 2026-04-09 Qiming Sun , Matthew R Hermes , Xiaojie Wu , Huanchen Zhai , Xing Zhang , Abdelrahman M. Ahmed , Juan José Aucar , Oliver J. Backhouse , Samragni Banerjee , Peng Bao , Nikolay A. Bogdanov , Kyle Bystrom , Frédéric Chapoton , Ning-Yuan Chen , Ivan Yu. Chernyshov , Helen S. Clifford , Sander Cohen-Janes , Zhi-Hao Cui , Yann D. Damour , Nike Dattani , Linus Bjarne Dittmer , Sebastian Ehlert , Janus Juul Eriksen , Francesco A. Evangelista , Simon A. Ewing , Ardavan Farahvash , Kevin Focke , Yang Gao , Kevin E. Gasperich , Nathan Gillispie , Jonas Greiner , Matthew R. Hennefarth , Jan Hermann , Christopher Hillenbrand , Joonatan Huhtasalo , Basil Ibrahim , Bhavnesh Jangid , Alireza Nejati Javaremi , Andrew J. Jenkins , Yu Jin , Daniel S. King , Derk Pieter Kooi , Jo S. Kurian , Henrik R. Larsson , Bryan Tak Gwong Lau , Seunghoon Lee , Susi Lehtola , Chenghan Li , Hao Li , Jiachen Li , Rui Li , Shuhang Li , Aleksandr O. Lykhin , Ankit Mahajan , Nastasia Mauger , Pablo del Mazo-Sevillano , Jonathan Moussa , Kousuke Nakano , Verena A. Neufeld , Linqing Peng , Hung Q. Pham , Peter Pinski , Pavel Pokhilko , Zhichen Pu , Yubing Qian , Stephen Jon Quiton , Wanja T. Schulze , Thais R. Scott , Aniruddha Seal , James D. Serna , James E. T. Smith , Kori E. Smyser , Terrence Stahl , Chong Sun , Kevin J. Sung , Egor Trushin , Shiv Upadhyay , Ethan A. Vo , Thijs Vogels , Shirong Wang , Tai Wang , Xiao Wang , Xubo Wang , Yuanheng Wang , Mark Williamson , Junjie Yang , Hong-Zhou Ye , Chia-Nan Yeh , Haiyang Yu , Jincheng Yu , Victor Wen-zhe Yu , Chaoqun Zhang , Dayou Zhang , Yichi Zhang , Zijun Zhao , Zehao Zhou , Andrew J. Zhu , Tianyu Zhu , Timothy C. Berkelbach , Laura Gagliardi , Sandeep Sharma , Alexander Sokolov , Garnet Kin-Lic Chan

We introduce the first version of GPU4PySCF, a module that provides GPU acceleration of methods in PySCF. As a core functionality, this provides a GPU implementation of two-electron repulsion integrals (ERIs) for contracted basis sets…

Computational Physics · Physics 2024-07-16 Rui Li , Qiming Sun , Xing Zhang , Garnet Kin-Lic Chan

We introduce an extension to the PySCF package which makes it automatically differentiable. The implementation strategy is discussed, and example applications are presented to demonstrate the automatic differentiation framework for quantum…

Chemical Physics · Physics 2024-06-19 Xing Zhang , Garnet Kin-Lic Chan

We describe a new open-source Python-based package for high accuracy correlated electron calculations using quantum Monte Carlo (QMC) in real space: PyQMC. PyQMC implements modern versions of QMC algorithms in an accessible format, enabling…

Molecular simulations are an important tool for research in physics, chemistry, and biology. The capabilities of simulations can be greatly expanded by providing access to advanced sampling methods and techniques that permit calculation of…

Quantum computers are becoming practical for computing numerous applications. However, simulating quantum computing on classical computers is still demanding yet useful because current quantum computers are limited because of computer…

Quantum Physics · Physics 2023-08-08 Jun Doi , Hiroshi Horii , Christopher Wood

Accurate quantum chemistry simulations remain challenging on classical computers for problems of industrially relevant sizes and there is reason for hope that quantum computing may help push the boundaries of what is technically feasible.…

Quantum Physics · Physics 2021-03-17 Vincent E. Elfving , Marta Millaruelo , José A. Gámez , Christian Gogolin

Manipulating quantum computing hardware in the presence of imperfect devices and control systems is a central challenge in realizing useful quantum computers. Susceptibility to noise limits the performance and capabilities of noisy…

We present PySCo, a fast and user-friendly Python library designed to run cosmological $N$-body simulations across various cosmological models, such as $\Lambda$CDM and $w_0w_a$CDM, and alternative theories of gravity, including $f(R)$,…

Cosmology and Nongalactic Astrophysics · Physics 2026-01-08 Michel-Andrès Breton

Quantum computing has the potential to revolutionize multiple fields by solving complex problems that can not be solved in reasonable time with current classical computers. Nevertheless, the development of quantum computers is still in its…

The inherently high computational cost of iterative self-consistent-field (SCF) methods proves to be a critical issue delaying visual and haptic feedback in real-time quantum chemistry. In this work, we introduce two schemes for SCF…

Chemical Physics · Physics 2016-03-10 Adrian H. Mühlbach , Alain C. Vaucher , Markus Reiher

Computational chemistry is the leading application to demonstrate the advantage of quantum computing in the near term. However, large-scale simulation of chemical systems on quantum computers is currently hindered due to a mismatch between…

Quantum Physics · Physics 2021-05-18 Gushu Li , Yunong Shi , Ali Javadi-Abhari

We report the implementation of electronic excited states for semi-empirical quantum chemical methods at the configuration interaction singles (CIS) and time-dependent Hartree-Fock (TDHF) level of theory in the PySEQM software. Built on…

Hardware generation languages (HGLs) increase hardware design productivity by creating parameterized modules and test benches. Unfortunately, existing tools are not widely adopted due to several demerits, including limited support for…

Hardware Architecture · Computer Science 2023-09-12 Jintao Sun , Zeke Wang , Tao Lu , Wenzhi Chen

Quantum computing enables parallelism through superposition and entanglement and offers advantages over classical computing architectures. However, due to the limitations of current quantum hardware in the noisy intermediate-scale quantum…

Quantum Physics · Physics 2025-09-09 Guolong Zhong , Yi Fan , Zhenyu Li

The need for computational resources grows as computational algorithms gain popularity in different sectors of the scientific community. This search has stimulated the development of several cloud platforms that abstract the complexity of…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-01-18 Henrique C. T. Santos , Luciano S. de Souza , Jonathan H. A. de Carvalho , Tiago A. E. Ferreira

Computational methods are the most effective tools we have besides scientific experiments to explore the properties of complex biological systems. Progress is slowing because digital silicon computers have reached their limits in terms of…

Quantum Physics · Physics 2020-04-03 Viv Kendon
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