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While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

Machine Learning · Computer Science 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

Machine learning for tabular data remains constrained by poor schema generalization, a challenge rooted in the lack of semantic understanding of structured variables. This challenge is particularly acute in domains like clinical medicine,…

Machine Learning · Computer Science 2026-05-05 Hongxi Mao , Wei Zhou , Mengting Jia , Tao Fang , Huan Gao , Bin Zhang , Shangyang Li

Large Language Models (LLMs) are increasingly used in clinical settings, where sensitivity to linguistic uncertainty can influence diagnostic interpretation and decision-making. Yet little is known about where such epistemic cues are…

Computation and Language · Computer Science 2025-12-01 Srivarshinee Sridhar , Raghav Kaushik Ravi , Kripabandhu Ghosh

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

We aim to present a comprehensive overview of the latest advancements in utilizing Large Language Models (LLMs) within the healthcare sector, emphasizing their transformative impact across various medical domains. LLMs have become pivotal…

Computation and Language · Computer Science 2026-04-07 Ummara Mumtaz , Awais Ahmed , Summaya Mumtaz

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

There is a growing need to semantically process and integrate clinical data from different sources for clinical research. This paper presents an approach to integrate EHRs from heterogeneous resources and generate integrated data in…

The development of Electronic Health Records summarization systems has revolutionized patient data management. Previous research advanced this field by adapting Large Language Models for clinical tasks, using diverse datasets to generate…

Computation and Language · Computer Science 2024-10-15 Ruvarashe Madzime , Clement Nyirenda

The advent of Large Language Models (LLMs) is promising and LLMs have been applied to numerous fields. However, it is not trivial to implement LLMs in the medical field, due to the high standards for precision and accuracy. Currently, the…

Information Retrieval · Computer Science 2024-12-04 Rishabh Goel

Automated clinical text anonymization has the potential to unlock the widespread sharing of textual health data for secondary usage while assuring patient privacy and safety. Despite the proposal of many complex and theoretically successful…

Computation and Language · Computer Science 2024-06-05 David Pissarra , Isabel Curioso , João Alveira , Duarte Pereira , Bruno Ribeiro , Tomás Souper , Vasco Gomes , André V. Carreiro , Vitor Rolla

Electronic medical records (EMRs) contain essential data for patient care and clinical research. With the diversity of structured and unstructured data in EHR, data visualization is an invaluable tool for managing and explaining these…

Databases · Computer Science 2025-06-17 Haodi Zhang , Siqi Ning , Qiyong Zheng , Jinyin Nie , Liangjie Zhang , Weicheng Wang , Yuanfeng Song

Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited. Existing benchmarks often rely on static datasets or…

Computation and Language · Computer Science 2026-05-29 Valentina Bui Muti , Eugénie Dulout , Ziquan Fu

Large language models (LLMs) show promise for improving the efficiency of qualitative analysis in large, multi-site health-services research. Yet methodological guidance for LLM integration into qualitative analysis and evidence of their…

Computation and Language · Computer Science 2026-01-22 Sasha Ronaghi , Emma-Louise Aveling , Maria Levis , Rachel Lauren Ross , Emily Alsentzer , Sara Singer

Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…

Computation and Language · Computer Science 2020-01-07 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

Computation and Language · Computer Science 2024-08-20 Qiuhao Lu , Rui Li , Andrew Wen , Jinlian Wang , Liwei Wang , Hongfang Liu

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

Large language models (LLMs) can generate natural language texts for various domains and tasks, but their potential for clinical text mining, a domain with scarce, sensitive, and imbalanced medical data, is underexplored. We investigate…

Computation and Language · Computer Science 2024-02-23 Rumeng Li , Xun Wang , Hong Yu

To address challenges in the digital economy's landscape of digital intelligence, large language models (LLMs) have been developed. Improvements in computational power and available resources have significantly advanced LLMs, allowing their…

Computation and Language · Computer Science 2024-05-24 Yanxin Zheng , Wensheng Gan , Zefeng Chen , Zhenlian Qi , Qian Liang , Philip S. Yu

Large Language Models have advanced clinical text classification, but their opaque predictions remain a critical barrier to practical adoption in research and clinical settings where investigators and physicians need to understand which…

Computation and Language · Computer Science 2025-11-18 Karthikeyan K , Raghuveer Thirukovalluru , David Carlson
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