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In scheduling problems, deterministic task durations are often assumed. This usually does not capture reality and may lead to schedules that are not robust to (small) changes to these task lengths. The use of stochastic task durations…

Optimization and Control · Mathematics 2026-05-25 Philip de Bruin , Bram Elderhorst , Marjan van den Akker , Han Hoogeveen

Patient length of stay (LoS) is a critical metric for evaluating the efficacy of hospital management. The primary objectives encompass to improve efficiency and reduce costs while enhancing patient outcomes and hospital capacity within the…

Machine Learning · Computer Science 2025-01-31 Tasfia Noor Chowdhury , Sanjida Afrin Mou , Kazi Naimur Rahman

We consider a distributed server system consisting of a large number of servers, each with limited capacity on multiple resources (CPU, memory, disk, etc.). Jobs with different rewards arrive over time and require certain amounts of…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-29 Konstantinos Psychas , Javad Ghaderi

Non-invasive estimation of respiratory physiology using computational algorithms promises to be a valuable technique for future clinicians to detect detrimental changes in patient pathophysiology. However, few clinical algorithms used to…

Quantitative Methods · Quantitative Biology 2021-09-22 Gregory Rehm , Jimmy Nguyen , Chelsea Gilbeau , Marc T Bomactao , Chen-Nee Chuah , Jason Adams

Standard reinforcement learning (RL) aims to find an optimal policy that identifies the best action for each state. However, in healthcare settings, many actions may be near-equivalent with respect to the reward (e.g., survival). We…

Machine Learning · Computer Science 2020-07-27 Shengpu Tang , Aditya Modi , Michael W. Sjoding , Jenna Wiens

Pragmatic trials increasingly define outcomes using real-world data such as electronic health records, where assessments are collected during routine care rather than at fixed timepoints. Consequently, these uncontrolled assessments may be…

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

A classical problem in appointment scheduling, with applications in health care, concerns the determination of the patients' arrival times that minimize a cost function that is a weighted sum of mean waiting times and mean idle times. One…

Probability · Mathematics 2020-05-08 Madelon A. de Kemp , Michel Mandjes , Neil Olver

This paper studies the scheduling of autonomous mobile robots (AMRs) at hospitals where the stochastic travel times and service times of AMRs are affected by the surrounding environment. The routes of AMRs are planned to minimize the daily…

Robotics · Computer Science 2023-11-27 Lulu Cheng , Ning Zhao , Mengge Yuan , Kan Wu

In a call center, staffing decisions must be made before the call arrival rate is known with certainty. Then, once the arrival rate becomes known, the call center may be over-staffed, in which case staff are being paid to be idle, or…

Probability · Mathematics 2014-04-14 Yasar Levent Kocaga , Mor Armony , Amy R. Ward

Platform trials are randomized clinical trials that allow simultaneous comparison of multiple interventions, usually against a common control. Arms to test experimental interventions may enter and leave the platform over time. This implies…

Methodology · Statistics 2024-04-12 Marta Bofill Roig , Ekkehard Glimm , Tobias Mielke , Martin Posch

Screening tasks that aim to identify a small subset of top alternatives from a large pool are common in business decision-making processes. These tasks often require substantial human effort to evaluate each alternative's performance,…

Machine Learning · Statistics 2025-04-28 Zaile Li , Weiwei Fan , L. Jeff Hong

We consider robust resource allocation of services in Clouds. More specifically, we consider the case of a large public or private Cloud platform that runs a relatively small set of large and independent services. These services are…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-10-22 Olivier Beaumont , Lionel Eyraud-Dubois , Paul Renaud-Goud

We introduce a new method for forecasting emergency call arrival rates that combines integer-valued time series models with a dynamic latent factor structure. Covariate information is captured via simple constraints on the factor loadings.…

Applications · Statistics 2011-07-26 David S. Matteson , Mathew W. McLean , Dawn B. Woodard , Shane G. Henderson

Large language models (LLMs) have significant potential to improve operational efficiency in operations management. Deploying these models requires specifying a policy that governs response quality, shapes user experience, and influences…

Machine Learning · Computer Science 2026-04-13 Mingjie Hu , Siyang Gao , Jian-qiang Hu , Enlu Zhou

As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often…

Machine Learning · Computer Science 2022-06-30 Yuqing Wang , Yun Zhao , Linda Petzold

Off-policy policy optimization is a challenging problem in reinforcement learning (RL). The algorithms designed for this problem often suffer from high variance in their estimators, which results in poor sample efficiency, and have issues…

Machine Learning · Computer Science 2020-09-15 Daoming Lyu , Qi Qi , Mohammad Ghavamzadeh , Hengshuai Yao , Tianbao Yang , Bo Liu

Current serverless offerings give users a limited degree of flexibility for configuring the resources allocated to their function invocations by either coupling memory and CPU resources together or providing no knobs at all. These…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-01 Muhammad Bilal , Marco Canini , Rodrigo Fonseca , Rodrigo Rodrigues

The increased use of electronic health records has made possible the automated extraction of medical policies from patient records to aid in the development of clinical decision support systems. We adapted a boosted Statistical Relational…

Artificial Intelligence · Computer Science 2020-01-14 Michael A. Skinner , Lakshmi Raman , Neel Shah , Abdelaziz Farhat , Sriraam Natarajan

We consider the problem of scheduling elective surgeries in a Children's Hospital, where disruptions due to emergencies and no-shows may arise. We account for two features that occur in many pediatric settings: i) that it is not uncommon…

Optimization and Control · Mathematics 2024-08-23 Martina Doneda , Gloria Pelizzo , Sara Costanzo , Giuliana Carello