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Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Alexis Perakis , Ali Gorji , Samriddhi Jain , Krishna Chaitanya , Simone Rizza , Ender Konukoglu

Contrastive learning has emerged as a transformative method for learning effective visual representations through the alignment of image and text embeddings. However, pairwise similarity computation in contrastive loss between image and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-25 Sachin Mehta , Maxwell Horton , Fartash Faghri , Mohammad Hossein Sekhavat , Mahyar Najibi , Mehrdad Farajtabar , Oncel Tuzel , Mohammad Rastegari

Existing vision-text contrastive learning like CLIP aims to match the paired image and caption embeddings while pushing others apart, which improves representation transferability and supports zero-shot prediction. However, medical…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Zifeng Wang , Zhenbang Wu , Dinesh Agarwal , Jimeng Sun

The scarcity of annotated data has sparked significant interest in unsupervised pre-training methods that leverage medical reports as auxiliary signals for medical visual representation learning. However, existing research overlooks the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Zhe Li , Laurence T. Yang , Bocheng Ren , Xin Nie , Zhangyang Gao , Cheng Tan , Stan Z. Li

Large vision-language contrastive models (VLCMs), such as CLIP, have become foundational, demonstrating remarkable success across a variety of downstream tasks. Despite their advantages, these models, akin to other foundational systems,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Haocheng Dai , Sarang Joshi

The success of large-scale contrastive vision-language pretraining (CLIP) has benefited both visual recognition and multimodal content understanding. The concise design brings CLIP the advantage in inference efficiency against other…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Shijie Geng , Jianbo Yuan , Yu Tian , Yuxiao Chen , Yongfeng Zhang

Contrastive Language-Image Pretraining (CLIP) has emerged as a novel paradigm to learn visual models from language supervision. While researchers continue to push the frontier of CLIP, reproducing these works remains challenging. This is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Yufeng Cui , Lichen Zhao , Feng Liang , Yangguang Li , Jing Shao

Contrastive learning has achieved great success in self-supervised visual representation learning, but existing approaches mostly ignored spatial information which is often crucial for visual representation. This paper presents…

Computer Vision and Pattern Recognition · Computer Science 2020-11-20 Xinyue Huo , Lingxi Xie , Longhui Wei , Xiaopeng Zhang , Hao Li , Zijie Yang , Wengang Zhou , Houqiang Li , Qi Tian

Contrastive Language-Image Pretraining (CLIP) models maximize the mutual information between text and visual modalities to learn representations. This makes the nature of the training data a significant factor in the efficacy of CLIP for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Maitreya Patel , Abhiram Kusumba , Sheng Cheng , Changhoon Kim , Tejas Gokhale , Chitta Baral , Yezhou Yang

Recent multimodal models such as Contrastive Language-Image Pre-training (CLIP) have shown remarkable ability to align visual and linguistic representations. However, domains where small visual differences carry large semantic significance,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hiroshi Sasaki

Multimodal models, such as the Contrastive Language-Image Pre-training (CLIP) model, have demonstrated remarkable success in aligning visual and linguistic representations. However, these models exhibit limitations when applied to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Hiroshi Sasaki

Large-scale multi-modal contrastive pre-training has demonstrated great utility to learn transferable features for a range of downstream tasks by mapping multiple modalities into a shared embedding space. Typically, this has employed…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Haoxuan You , Luowei Zhou , Bin Xiao , Noel Codella , Yu Cheng , Ruochen Xu , Shih-Fu Chang , Lu Yuan

Contrastive Language-Image Pretraining (CLIP) achieves strong generalization in vision-language tasks by aligning images and texts in a shared embedding space. However, recent findings show that CLIP-like models still underutilize…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Weiheng Zhao , Zilong Huang , Jiashi Feng , Xinggang Wang

Contrastive cross-modal models such as CLIP and CLAP aid various vision-language (VL) and audio-language (AL) tasks. However, there has been limited investigation of and improvement in their language encoder, which is the central component…

Computation and Language · Computer Science 2023-10-23 Mengjie Zhao , Junya Ono , Zhi Zhong , Chieh-Hsin Lai , Yuhta Takida , Naoki Murata , Wei-Hsiang Liao , Takashi Shibuya , Hiromi Wakaki , Yuki Mitsufuji

Recent progress has shown that large-scale pre-training using contrastive image-text pairs can be a promising alternative for high-quality visual representation learning from natural language supervision. Benefiting from a broader source of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yongming Rao , Wenliang Zhao , Guangyi Chen , Yansong Tang , Zheng Zhu , Guan Huang , Jie Zhou , Jiwen Lu

Contrastive Language-Image Pre-training (CLIP) has been a celebrated method for training vision encoders to generate image/text representations facilitating various applications. Recently, CLIP has been widely adopted as the vision backbone…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Hong-You Chen , Zhengfeng Lai , Haotian Zhang , Xinze Wang , Marcin Eichner , Keen You , Meng Cao , Bowen Zhang , Yinfei Yang , Zhe Gan

Contrastive Language-Image Pre-training (CLIP)~\citep{radford2021learning} has emerged as a pivotal model in computer vision and multimodal learning, achieving state-of-the-art performance at aligning visual and textual representations…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Shaoan Xie , Lingjing Kong , Yujia Zheng , Yu Yao , Zeyu Tang , Eric P. Xing , Guangyi Chen , Kun Zhang

Contrastive learning and self-supervised techniques have gained prevalence in computer vision for the past few years. It is essential for medical image analysis, which is often notorious for its lack of annotations. Most existing…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Jun Li , Quan Quan , S. Kevin Zhou

Detectingandsegmentingobjectswithinwholeslideimagesis essential in computational pathology workflow. Self-supervised learning (SSL) is appealing to such annotation-heavy tasks. Despite the extensive benchmarks in natural images for dense…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Jiawei Yang , Hanbo Chen , Yuan Liang , Junzhou Huang , Lei He , Jianhua Yao

Recent advances in contrastive representation learning over paired image-text data have led to models such as CLIP that achieve state-of-the-art performance for zero-shot classification and distributional robustness. Such models typically…

Computer Vision and Pattern Recognition · Computer Science 2022-10-28 Shashank Goel , Hritik Bansal , Sumit Bhatia , Ryan A. Rossi , Vishwa Vinay , Aditya Grover
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