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Retrieval-Augmented Generation (RAG) has emerged as a powerful paradigm for enhancing the capabilities of large language models. However, existing RAG evaluation predominantly focuses on text retrieval and relies on opaque, end-to-end…

Information Retrieval · Computer Science 2025-05-19 Chuan Xu , Qiaosheng Chen , Yutong Feng , Gong Cheng

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Large Language Models (LLMs) are proficient at generating coherent and contextually relevant text but face challenges when addressing knowledge-intensive queries in domain-specific and factual question-answering tasks. Retrieval-augmented…

Information Retrieval · Computer Science 2024-10-08 Garima Agrawal , Tharindu Kumarage , Zeyad Alghamdi , Huan Liu

Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

Computation and Language · Computer Science 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Advanced Multimodal Large Language Models (MLLMs) struggle with recent Knowledge-based VQA tasks, such as INFOSEEK and Encyclopedic-VQA, due to their limited and frozen knowledge scope, often leading to ambiguous and inaccurate responses.…

Artificial Intelligence · Computer Science 2024-11-25 Tao Zhang , Ziqi Zhang , Zongyang Ma , Yuxin Chen , Zhongang Qi , Chunfeng Yuan , Bing Li , Junfu Pu , Yuxuan Zhao , Zehua Xie , Jin Ma , Ying Shan , Weiming Hu

Retrieval-augmented generation (RAG) is a paradigm that augments large language models (LLMs) with external knowledge to tackle knowledge-intensive question answering. While several benchmarks evaluate Multimodal LLMs (MLLMs) under…

Computation and Language · Computer Science 2025-08-18 Yin Wu , Quanyu Long , Jing Li , Jianfei Yu , Wenya Wang

While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

Large Vision-Language Models (LVLMs) have made remarkable strides in multimodal tasks such as visual question answering, visual grounding, and complex reasoning. However, they remain limited by static training data, susceptibility to…

Artificial Intelligence · Computer Science 2025-08-27 Chan-Wei Hu , Yueqi Wang , Shuo Xing , Chia-Ju Chen , Suofei Feng , Ryan Rossi , Zhengzhong Tu

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

Computation and Language · Computer Science 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

Large Language Models (LLMs) have shown remarkable capabilities across diverse tasks, yet they face inherent limitations such as constrained parametric knowledge and high retraining costs. Retrieval-Augmented Generation (RAG) augments the…

Information Retrieval · Computer Science 2025-08-26 Leqian Li , Dianxi Shi , Jialu Zhou , Xinyu Wei , Mingyue Yang , Songchang Jin , Shaowu Yang

We introduce a novel retrieval-augmented generation (RAG) framework tailored for multihop question answering. First, our system uses large language model (LLM) to decompose complex multihop questions into a sequence of single-hop…

Computation and Language · Computer Science 2025-08-14 Seokgi Lee

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Large language models (LLMs) perform well in medical QA, but their effectiveness in Japanese contexts is limited due to privacy constraints that prevent the use of commercial models like GPT-4 in clinical settings. As a result, recent…

Computation and Language · Computer Science 2025-04-29 Yingjian Chen , Feiyang Li , Xingyu Song , Tianxiao Li , Zixin Xu , Xiujie Chen , Issey Sukeda , Irene Li

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

Computation and Language · Computer Science 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes

The retrieval-augmented generation (RAG) enables retrieval of relevant information from an external knowledge source and allows large language models (LLMs) to answer queries over previously unseen document collections. However, it was…

Computation and Language · Computer Science 2025-04-03 Mykhailo Poliakov , Nadiya Shvai

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Large Language Models (LLMs) have excelled in multi-hop question-answering (M-QA) due to their advanced reasoning abilities. However, the impact of the inherent reasoning structures on LLM M-QA performance remains unclear, largely due to…

Multimodal Knowledge Graphs (MMKGs), which represent explicit knowledge across multiple modalities, play a pivotal role by complementing the implicit knowledge of Multimodal Large Language Models (MLLMs) and enabling more grounded reasoning…

Computation and Language · Computer Science 2025-09-29 Hyeongcheol Park , Jiyoung Seo , MinHyuk Jang , Hogun Park , Ha Dam Baek , Gyusam Chang , Hyeonsoo Im , Sangpil Kim

This work presents a novel architecture for building Retrieval-Augmented Generation (RAG) systems to improve Question Answering (QA) tasks from a target corpus. Large Language Models (LLMs) have revolutionized the analyzing and generation…

Computation and Language · Computer Science 2025-01-09 Binita Saha , Utsha Saha , Muhammad Zubair Malik