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Related papers: Mitigating Confounding in Speech-Based Dementia De…

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Large language models (LLMs) have emerged as powerful tools for medical information retrieval, yet their accuracy and depth remain limited in specialized domains such as Alzheimer's disease (AD), a growing global health challenge. To…

Machine learning has shown promise for automatic detection of Alzheimer's disease (AD) through speech; however, efforts are hampered by a scarcity of data, especially in languages other than English. We propose a method to learn a…

Computation and Language · Computer Science 2019-06-04 Bai Li , Yi-Te Hsu , Frank Rudzicz

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Ali Nawaz , Syed Muhammad Anwar , Rehan Liaqat , Javid Iqbal , Ulas Bagci , Muhammad Majid

Dementia diagnosis requires a series of different testing methods, which is complex and time-consuming. Early detection of dementia is crucial as it can prevent further deterioration of the condition. This paper utilizes a speech…

Computation and Language · Computer Science 2023-12-18 Zih-Jyun Lin , Yi-Ju Chen , Po-Chih Kuo , Likai Huang , Chaur-Jong Hu , Cheng-Yu Chen

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and delay progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical screening…

Machine Learning · Computer Science 2022-08-09 Yi Wang , Tianzi Wang , Zi Ye , Lingwei Meng , Shoukang Hu , Xixin Wu , Xunying Liu , Helen Meng

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In this paper, we propose a novel approach…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-29 Yu Pu , Wei-Qiang Zhang

The proliferation of healthcare data has brought the opportunities of applying data-driven approaches, such as machine learning methods, to assist diagnosis. Recently, many deep learning methods have been shown with impressive successes in…

Machine Learning · Statistics 2018-09-03 Haohan Wang , Zhenglin Wu , Eric P. Xing

Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zobia Batool , Diala Lteif , Vijaya B. Kolachalama , Huseyin Ozkan , Erchan Aptoula

Compared to other clinical screening techniques, speech-and-language-based automated Alzheimer's disease (AD) detection methods are characterized by their non-invasiveness, cost-effectiveness, and convenience. Previous studies have…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-10 Yin-Long Liu , Rui Feng , Jia-Hong Yuan , Zhen-Hua Ling

Early detection of Alzheimer's Dementia (AD) and Mild Cognitive Impairment (MCI) is critical for timely intervention, yet current diagnostic approaches remain resource-intensive and invasive. Speech, encompassing both acoustic and…

Alzheimer's disease (AD) is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline. With the aging population, there has been much interest in automated methods for cognitive impairment…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-07 Bastiaan Tamm , Rik Vandenberghe , Hugo Van hamme

Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Mohammad Rafsan , Tamer Oraby , Upal Roy , Sanjeev Kumar , Hansapani Rodrigo

Alzheimer's dementia (AD) is of increasing concern as populations achieve longer lifespans. Many of the recent failed AD clinical trials recruiting cognitively intact individuals had a low number of AD events and were thus underpowered.…

Methodology · Statistics 2025-03-21 Julia Gallini , Zach Baucom , Yorghos Tripodis

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

The evolution of deep learning and artificial intelligence has significantly reshaped technological landscapes. However, their effective application in crucial sectors such as medicine demands more than just superior performance, but…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yasmine Mustafa , Tie Luo

Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Ahsan Bin Tufail , Qiu-Na Zhang , Yong-Kui Ma

Dementia is a neurological syndrome marked by cognitive decline. Alzheimer's disease (AD) and Frontotemporal dementia (FTD) are the common forms of dementia, each with distinct progression patterns. EEG, a non-invasive tool for recording…

Signal Processing · Electrical Eng. & Systems 2024-08-21 Shivani Ranjan , Ayush Tripathi , Harshal Shende , Robin Badal , Amit Kumar , Pramod Yadav , Deepak Joshi , Lalan Kumar

Recent breakthroughs in Automatic Speech Recognition (ASR) have enabled fully automated Alzheimer's Disease (AD) detection using ASR transcripts. Nonetheless, the impact of ASR errors on AD detection remains poorly understood. This paper…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-27 Yin-Long Liu , Rui Feng , Jia-Xin Chen , Yi-Ming Wang , Jia-Hong Yuan , Zhen-Hua Ling

Frontotemporal dementia and Alzheimer's disease are two common forms of dementia and are easily misdiagnosed as each other due to their similar pattern of clinical symptoms. Differentiating between the two dementia types is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Da Ma , Donghuan Lu , Karteek Popuri , Mirza Faisal Beg

INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…