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Retrieval-Augmented Generation (RAG) mitigates factual errors and hallucinations in Large Language Models (LLMs) for question-answering (QA) by incorporating external knowledge. However, existing adaptive RAG methods rely on LLMs to predict…

Computation and Language · Computer Science 2025-04-08 Ruobing Wang , Qingfei Zhao , Yukun Yan , Daren Zha , Yuxuan Chen , Shi Yu , Zhenghao Liu , Yixuan Wang , Shuo Wang , Xu Han , Zhiyuan Liu , Maosong Sun

Retrieval-augmented generation combined with reinforcement learning has shown promise for grounding large language models in trustworthy medical evidence. However, existing methods rely on exact-match binary rewards, which in clinical…

Artificial Intelligence · Computer Science 2026-05-28 Yuwei Miao , Gen Li , Yunsheng Zeng , Xiandong Li , Yujin Wang , Siyu Chen , Luning Wang , Yunhao Qiao , Junfeng Wang , Jianwei Lv , Bo Yuan

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

In recent years, accurately and quickly deploying medical large language models (LLMs) has become a trend. Among these, retrieval-augmented generation (RAG) has garnered attention due to rapid deployment and privacy protection. However, the…

Computation and Language · Computer Science 2025-08-06 Penglei Sun , Yixiang Chen , Xiang Li , Xiaowen Chu

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Large language models (LLMs) have become a disruptive force in the industry, introducing unprecedented capabilities in natural language processing, logical reasoning and so on. However, the challenges of knowledge updates and hallucination…

Machine Learning · Computer Science 2025-04-22 Chunjing Gan , Dan Yang , Binbin Hu , Ziqi Liu , Yue Shen , Zhiqiang Zhang , Jian Wang , Jun Zhou

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Background: Several studies show that large language models (LLMs) struggle with phenotype-driven gene prioritization for rare diseases. These studies typically use Human Phenotype Ontology (HPO) terms to prompt foundation models like GPT…

Computation and Language · Computer Science 2026-02-19 Zhanliang Wang , Da Wu , Quan Nguyen , Kai Wang

Retrieval-Augmented Generation (RAG) has emerged as a powerful paradigm for enhancing the capabilities of large language models. However, existing RAG evaluation predominantly focuses on text retrieval and relies on opaque, end-to-end…

Information Retrieval · Computer Science 2025-05-19 Chuan Xu , Qiaosheng Chen , Yutong Feng , Gong Cheng

Retrieval-Augmented Generation (RAG) enhances the reasoning ability of Large Language Models (LLMs) by dynamically integrating external knowledge, thereby mitigating hallucinations and strengthening contextual grounding for structured data…

Artificial Intelligence · Computer Science 2026-02-24 Sen Zhao , Lincheng Zhou , Yue Chen , Ding Zou

Retrieval-augmented generation (RAG) improves the response quality of large language models (LLMs) by retrieving knowledge from external databases. Typical RAG approaches split the text database into chunks, organizing them in a flat…

Computation and Language · Computer Science 2025-11-18 Boyu Chen , Zirui Guo , Zidan Yang , Yuluo Chen , Junze Chen , Zhenghao Liu , Chuan Shi , Cheng Yang

Retrieval augmented generation (RAG) has been applied in many scenarios to augment large language models (LLMs) with external documents provided by retrievers. However, a semantic gap exists between LLMs and retrievers due to differences in…

Computation and Language · Computer Science 2024-10-31 Fuda Ye , Shuangyin Li , Yongqi Zhang , Lei Chen

Retrieval-Augmented Generation (RAG) has been shown to enhance the factual accuracy of Large Language Models (LLMs), but existing methods often suffer from limited reasoning capabilities in effectively using the retrieved evidence,…

Computation and Language · Computer Science 2024-10-03 Shayekh Bin Islam , Md Asib Rahman , K S M Tozammel Hossain , Enamul Hoque , Shafiq Joty , Md Rizwan Parvez

Clinical decision support requires not only correct answers but also clinically valid reasoning. We propose Differential Reasoning Learning (DRL), a framework that improves clinical agents by learning from reasoning discrepancies. From…

Artificial Intelligence · Computer Science 2026-02-11 Jinsong Liu , Yuhang Jiang , Ramayya Krishnan , Rema Padman , Yiye Zhang , Jiang Bian

Advances in Large Language Models revolutionized medical education by enabling scalable and efficient learning solutions. This paper presents a pipeline employing Retrieval-Augmented Generation (RAG) system to prepare comments generation…

Computation and Language · Computer Science 2025-03-05 Jeremi I. Kaczmarek , Jakub Pokrywka , Krzysztof Biedalak , Grzegorz Kurzyp , Łukasz Grzybowski

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Graph-based Retrieval-Augmented Generation (RAG) methods have significantly enhanced the performance of large language models (LLMs) in domain-specific tasks. However, existing RAG methods do not adequately utilize the naturally inherent…

Computation and Language · Computer Science 2025-09-29 Haoyu Huang , Yongfeng Huang , Junjie Yang , Zhenyu Pan , Yongqiang Chen , Kaili Ma , Hongzhi Chen , James Cheng

Retrieval-Augmented Generation (RAG) has gained significant popularity in modern Large Language Models (LLMs) due to its effectiveness in introducing new knowledge and reducing hallucinations. However, the deep understanding of RAG remains…

Computation and Language · Computer Science 2024-10-07 Jingyu Liu , Jiaen Lin , Yong Liu

Effectively retrieving, reasoning, and understanding multimodal information remains a critical challenge for agentic systems. Traditional Retrieval-augmented Generation (RAG) methods rely on linear interaction histories, which struggle to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Qiuchen Wang , Shihang Wang , Yu Zeng , Qiang Zhang , Fanrui Zhang , Zhuoning Guo , Bosi Zhang , Wenxuan Huang , Lin Chen , Zehui Chen , Pengjun Xie , Ruixue Ding