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The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhaozhi Xie , Bochen Guan , Weihao Jiang , Muyang Yi , Yue Ding , Hongtao Lu , Lei Zhang

The Segment Anything Model (SAM) is widely used for segmenting a diverse range of objects in natural images from simple user prompts like points or bounding boxes. However, SAM's performance decreases substantially when applied to…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Tristan Piater , Björn Barz , Alexander Freytag

The advent of large models, also known as foundation models, has significantly transformed the AI research landscape, with models like Segment Anything (SAM) achieving notable success in diverse image segmentation scenarios. Despite its…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Tianrun Chen , Ankang Lu , Lanyun Zhu , Chaotao Ding , Chunan Yu , Deyi Ji , Zejian Li , Lingyun Sun , Papa Mao , Ying Zang

Although recent years have witnessed significant advancements in medical image segmentation, the pervasive issue of domain shift among medical images from diverse centres hinders the effective deployment of pre-trained models. Many…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Ziyang Chen , Yiwen Ye , Yongsheng Pan , Yong Xia

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

The emergence of large models, also known as foundation models, has brought significant advancements to AI research. One such model is Segment Anything (SAM), which is designed for image segmentation tasks. However, as with other foundation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Tianrun Chen , Lanyun Zhu , Chaotao Ding , Runlong Cao , Yan Wang , Zejian Li , Lingyun Sun , Papa Mao , Ying Zang

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi

In medical image segmentation tasks, the domain gap caused by the difference in data collection between training and testing data seriously hinders the deployment of pre-trained models in clinical practice. Continual Test-Time Adaptation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Xiaogang Du , Jiawei Zhang , Tongfei Liu , Tao Lei , Yingbo Wang

The Segment Anything Model (SAM) demonstrates impressive zero-shot segmentation ability on natural images but encounters difficulties in medical imaging due to domain shifts, anatomical variability, and its reliance on user-provided…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yingzhen Hu , Yiheng Zhong , Ruobing Li , Yingxue Su , Jiabao An , Feilong Tang , Jionglong Su , Imran Razzak

In this study, we evaluate the performance of the Segment Anything Model (SAM) in clinical radiotherapy. Our results indicate that SAM's 'segment anything' mode can achieve clinically acceptable segmentation results in most organs-at-risk…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Lian Zhang , Zhengliang Liu , Lu Zhang , Zihao Wu , Xiaowei Yu , Jason Holmes , Hongying Feng , Haixing Dai , Xiang Li , Quanzheng Li , Dajiang Zhu , Tianming Liu , Wei Liu

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

This paper tackles a novel yet challenging problem: how to transfer knowledge from the emerging Segment Anything Model (SAM) -- which reveals impressive zero-shot instance segmentation capacity -- to learn a compact panoramic semantic…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Weiming Zhang , Yexin Liu , Xu Zheng , Lin Wang

The universality of deep neural networks across different modalities and their generalization capabilities to unseen domains play an essential role in medical image segmentation. The recent segment anything model (SAM) has demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Qing Xu , Jiaxuan Li , Xiangjian He , Chenxin Li , Fiseha B. Tesem , Wenting Duan , Zhen Chen , Rong Qu , Jonathan M. Garibaldi , Chang Wen Chen

Segment anything model (SAM) has demonstrated excellent generalizability in common vision scenarios, yet falling short of the ability to understand specialized data. Recently, several methods have combined parameter-efficient techniques…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Yiran Song , Qianyu Zhou , Xuequan Lu , Zhiwen Shao , Lizhuang Ma

The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

Medical image segmentation is a critical task in computer-aided diagnosis and treatment planning. However, deep learning models often struggle to generalize across datasets due to domain shifts arising from variations in imaging protocols,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Phuoc-Nguyen Bui , Van-Nguyen Pham , Duc-Tai Le , Junghyun Bum , Hyunseung Choo

Semi-supervised learning has attracted much attention due to its less dependence on acquiring abundant annotations from experts compared to fully supervised methods, which is especially important for medical image segmentation which…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yichi Zhang , Jin Yang , Yuchen Liu , Yuan Cheng , Yuan Qi

Recent advances in segmentation foundation models have enabled accurate and efficient segmentation across a wide range of natural images and videos, but their utility to medical data remains unclear. In this work, we first present a…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Jun Ma , Sumin Kim , Feifei Li , Mohammed Baharoon , Reza Asakereh , Hongwei Lyu , Bo Wang

The Segment Anything Model (SAM) serves as a fundamental model for semantic segmentation and demonstrates remarkable generalization capabilities across a wide range of downstream scenarios. In this empirical study, we examine SAM's…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 An Wang , Mobarakol Islam , Mengya Xu , Yang Zhang , Hongliang Ren

Test-time adaptation (TTA) has emerged as a promising paradigm to handle the domain shifts at test time for medical images from different institutions without using extra training data. However, existing TTA solutions for segmentation tasks…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Chuyan Zhang , Hao Zheng , Xin You , Yefeng Zheng , Yun Gu
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