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Mechanical stresses in soft materials across different length scales play a fundamental role in understanding the function of biological systems and in the use of artificial materials for engineering soft machines and biomedical devices.…

Soft Condensed Matter · Physics 2025-06-05 Zhaoyi Zhang , Guo-Yang Li , Yuxuan Jiang , Yang Zheng , Artur L. Gower , Michel Destrade , Yanping Cao

Pressure ulcers are a severe disease affecting patients that are bedridden or in a wheelchair bound for long periods of time. These wounds can develop in the deep layers of the skin of specific parts of the body, mostly on heels or sacrum,…

Knowing the stress within a soft material is of fundamental interest to basic research and practical applications, such as soft matter devices, biomaterial engineering, and medical sciences. However, it is challenging to measure stress…

Soft Condensed Matter · Physics 2022-01-07 Guo-Yang Li , Artur L. Gower , Michel Destrade , Seok-Hyun Yun

Stress is a complex issue with wide-ranging physical and psychological impacts on human daily performance. Specifically, acute stress detection is becoming a valuable application in contextual human understanding. Two common approaches to…

Machine Learning · Computer Science 2022-03-21 Van-Tu Ninh , Manh-Duy Nguyen , Sinéad Smyth , Minh-Triet Tran , Graham Healy , Binh T. Nguyen , Cathal Gurrin

Conventional imaging of diagnostic ultrasound is widely used. Although it makes the differences in the soft tissues echogenicities' apparent and clear, it fails in describing and estimating the soft tissue mechanical properties. It cannot…

Medical Physics · Physics 2022-10-07 Hassan M. Ahmed

Mechanical stress within biological tissue can indicate an anomaly, or can be vital of its function, such as stresses in arteries. Measuring these stresses in tissue is challenging due to the complex, and often unknown, nature of the…

Soft Condensed Matter · Physics 2024-02-27 Harold Berjamin , Artur L. Gower

Excessive loads near wounds produce pathological scarring and other complications. Presently, stress cannot easily be measured by surgeons in the operating room. Instead, surgeons rely on intuition and experience. Predictive computational…

Medical Physics · Physics 2020-10-07 Casey Stowers , Taeksang Lee , Ilias Bilionis , Arun Gosain , Adrian Buganza Tepole

The stress detection problem is receiving great attention in related research communities. This is due to its essential part in behavioral studies for many serious health problems and physical illnesses. There are different methods and…

Human-Computer Interaction · Computer Science 2020-07-03 Seyed Amir Hossein Aqajari , Emad Kasaeyan Naeini , Milad Asgari Mehrabadi , Sina Labbaf , Amir M. Rahmani , Nikil Dutt

In the course of animal development, the shape of tissue emerges in part from mechanical and biochemical interactions between cells. Measuring stress in tissue is essential for studying morphogenesis and its physical constraints.…

Quantitative Methods · Quantitative Biology 2013-01-21 S. Ishihara , K. Sugimura , S. J. Cox , I. Bonnet , Y. Bellaiche , F. Graner

In medicolegal situations, the consequences of a stabbing incident are described in terms that are qualitative without being quantitative. Here, the mechanical variables involved in knife-tissue penetration events are used to determine the…

Classical Physics · Physics 2008-11-25 Michael D. Gilchrist , Stephen Keenan , Michael Curtis , Mary Cassidy , Greg Byrne , Michel Destrade

Measuring stress levels in loaded structures is crucial to assess and monitor their health, and to predict the length of their remaining structural life. However, measuring stress non-destructively has proved quite challenging. Many…

Classical Physics · Physics 2021-02-03 Guo-Yang Li , Artur Lewis Gower , Michel Destrade

In vivo skin exhibits viscoelastic, hyper-elastic and non-linear characteristics. It is under a constant non-equibiaxial tension in its natural configuration and is reinforced with oriented collagen fibers, giving rise to anisotropic…

Biological Physics · Physics 2025-06-04 Matt Nagle , Susan Price , Antonia Trotta , Michel Destrade , Michael Fop , Aisling Ní Annaidh

Shear wave elastography (SWE) is a promising imaging modality for mechanical characterization of tissues, offering biomarkers with potential for early and precise diagnosis. While various methods have been developed to extract mechanical…

Soft Condensed Matter · Physics 2025-07-01 Yuxuan Jiang , Guo-Yang Li , Zhaoyi Zhang , Shiyu Ma , Yanping Cao , Seok-Hyun Yun

During morphogenesis, the shape of a tissue emerges from collective cellular behaviors, which are in part regulated by mechanical and biochemical interactions between cells. Quantification of force and stress is therefore necessary to…

Tissues and Organs · Quantitative Biology 2014-02-19 K. Sugimura , Y. Bellaïche , F. Graner , P. Marcq , S. Ishihara

Evaluating the mechanical response of fiber-reinforced composites can be extremely time consuming and expensive. Machine learning (ML) techniques offer a means for faster predictions via models trained on existing input-output pairs and…

Materials Science · Physics 2024-10-03 Yixuan Sun , Imad Hanhan , Michael D. Sangid , Guang Lin

Microstructural heterogeneity affects the macro-scale behavior of materials. Conversely, load distribution at the macro-scale changes the microstructural response. These up-scaling and down-scaling relations are often modeled using…

Materials Science · Physics 2023-06-13 Ashwini Gupta , Anindya Bhaduri , Lori Graham-Brady

Studying the peeling behaviour of adhesives on skin is vital for advancing biomedical applications such as medical adhesives and transdermal patches. Traditional methods like experimental testing and finite element method (FEM), though…

Medical Physics · Physics 2025-06-26 Ashish Masarkar , Rakesh Gupta , Naga Neehar Dingari , Beena Rai

The measurement of shear stress acting on a biologically relevant surface is a challenging problem, particularly in the complex environment of, for example, the vasculature. While an experimental method for the direct detection of wall…

Quantitative Methods · Quantitative Biology 2017-08-03 Meurig Thomas Gallagher , Cara Victoria Neal , Kenton P. Arkill , David John Smith

In this work, we develop Gaussian process regression (GPR) models of hyperelastic material behavior. First, we consider the direct approach of modeling the components of the Cauchy stress tensor as a function of the components of the Finger…

Machine Learning · Statistics 2019-12-24 Ari Frankel , Reese Jones , Laura Swiler

Stress is widely recognized as a major contributor to a variety of health issues. Stress prediction using biosignal data recorded by wearables is a key area of study in mobile sensing research because real-time stress prediction can enable…

Machine Learning · Computer Science 2023-08-14 Tanvir Islam , Peter Washington
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