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Although temporal coding through spike-time patterns has long been of interest in neuroscience, the specific structures that could be useful for spike-time codes remain highly unclear. Here, we introduce a new analytical approach, using…

Neurons and Cognition · Quantitative Biology 2022-11-15 Federico W. Pasini , Alexandra N. Busch , Ján Mináč , Krishnan Padmanabhan , Lyle Muller

Grid cells in medial entorhinal cortex are believed to play a key role in path integration. However, the relation between path integration and the grid-like arrangement of their firing field remains unclear. We provide theoretical evidence…

Neural and Evolutionary Computing · Computer Science 2016-06-06 Reza Moazzezi

Kernel-based learning methods can dramatically increase the storage capacity of Hopfield networks, yet the dynamical mechanisms behind this enhancement remain poorly understood. We address this gap by combining a geometric characterization…

Machine Learning · Computer Science 2026-04-13 Akira Tamamori

Unsupervised text encoding models have recently fueled substantial progress in NLP. The key idea is to use neural networks to convert words in texts to vector space representations based on word positions in a sentence and their contexts,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Gengchen Mai , Krzysztof Janowicz , Bo Yan , Rui Zhu , Ling Cai , Ni Lao

The hippocampal-entorhinal complex plays a major role in the organization of memory and thought. The formation of and navigation in cognitive maps of arbitrary mental spaces via place and grid cells can serve as a representation of memories…

Neurons and Cognition · Quantitative Biology 2022-10-31 Paul Stoewer , Achim Schilling , Andreas Maier , Patrick Krauss

Spatial awareness in mammals is based on internalized representations of the environment---cognitive maps---encoded by networks of spiking neurons. Although behavioral studies suggest that these maps can remain stable for long periods, it…

Neurons and Cognition · Quantitative Biology 2019-09-18 Yuri Dabaghian

In many normative theories of synaptic plasticity, weight updates implicitly depend on the chosen parametrization of the weights. This problem relates, for example, to neuronal morphology: synapses which are functionally equivalent in terms…

Neurons and Cognition · Quantitative Biology 2022-02-25 Elena Kreutzer , Walter M. Senn , Mihai A. Petrovici

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Neurons and Cognition · Quantitative Biology 2022-05-17 Ivan Y. Tyukin , Alexander N. Gorban , Carlos Calvo , Julia Makarova , Valeri A. Makarov

To afford flexible behaviour, the brain must build internal representations that mirror the structure of variables in the external world. For example, 2D space obeys rules: the same set of actions combine in the same way everywhere (step…

Neurons and Cognition · Quantitative Biology 2025-03-04 William Dorrell , Peter E. Latham , Timothy E. J. Behrens , James C. R. Whittington

Encoding information about continuous variables using noisy computational units is a challenge; nonetheless, asymptotic theory shows that combining multiple periodic scales for coding can be highly precise despite the corrupting influence…

Neurons and Cognition · Quantitative Biology 2013-08-22 Alexander Mathis , Andreas V. M. Herz , Martin B. Stemmler

In this paper we developed a hierarchical network model, called Hierarchical Prediction Network (HPNet), to understand how spatiotemporal memories might be learned and encoded in the recurrent circuits in the visual cortical hierarchy for…

Neural and Evolutionary Computing · Computer Science 2021-10-04 Jielin Qiu , Ge Huang , Tai Sing Lee

The natural gradient field is a vector field that lives on a model equipped with a distinguished Riemannian metric, e.g. the Fisher-Rao metric, and represents the direction of steepest ascent of an objective function on the model with…

Machine Learning · Computer Science 2022-07-01 Jesse van Oostrum , Johannes Müller , Nihat Ay

About a decade ago grid cells were discovered in the medial entorhinal cortex of rat. Their peculiar firing patterns, which correlate with periodic locations in the environment, led to early hypothesis that grid cells may provide some form…

Neurons and Cognition · Quantitative Biology 2018-10-18 Jochen Kerdels , Gabriele Peters

Discussions of the hippocampus often focus on place cells, but many neurons are not place cells in any given environment. Here we describe the collective activity in such mixed populations, treating place and non-place cells on the same…

Neurons and Cognition · Quantitative Biology 2019-01-01 Leenoy Meshulam , Jeffrey L. Gauthier , Carlos D. Brody , David W. Tank , William Bialek

Learning and interpreting the structure of the environment is an innate feature of biological systems, and is integral to guiding flexible behaviours for evolutionary viability. The concept of a cognitive map has emerged as one of the…

Neurons and Cognition · Quantitative Biology 2022-02-04 James C. R. Whittington , David McCaffary , Jacob J. W. Bakermans , Timothy E. J. Behrens

Work on deep learning-based models of grid cells suggests that grid cells generically and robustly arise from optimizing networks to path integrate, i.e., track one's spatial position by integrating self-velocity signals. In previous work,…

Neurons and Cognition · Quantitative Biology 2023-12-19 Rylan Schaeffer , Mikail Khona , Sanmi Koyejo , Ila Rani Fiete

Networks of neurons in the brain encode preferred patterns of neural activity via their synaptic connections. Despite receiving considerable attention, the precise relationship between network connectivity and encoded patterns is still…

Neurons and Cognition · Quantitative Biology 2015-02-25 Carina Curto , Anda Degeratu , Vladimir Itskov

High-dimensional interpolation problems appear in various applications of uncertainty quantification, stochastic optimization and machine learning. Such problems are computationally expensive and request the use of adaptive grid generation…

Numerical Analysis · Mathematics 2025-05-26 Hendrik Wilka , Jens Lang

Recent advances in experimental techniques enable the simultaneous recording of activity from thousands of neurons in the brain, presenting both an opportunity and a challenge: to build meaningful, scalable models of large neural…

Biological Physics · Physics 2025-08-05 Luca Di Carlo , Francesca Mignacco , Christopher W. Lynn , William Bialek

The mammalian hippocampus plays a principal role in producing a cognitive map of space---an internalized representation of the animal's environment. The neuronal mechanisms producing this map depend primarily on the temporal structure of…

Neurons and Cognition · Quantitative Biology 2016-03-22 Edward Basso , Mamiko Arai , Yuri Dabaghian