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We propose a deformable registration algorithm based on unsupervised learning of a low-dimensional probabilistic parameterization of deformations. We model registration in a probabilistic and generative fashion, by applying a conditional…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Julian Krebs , Tommaso Mansi , Boris Mailhé , Nicholas Ayache , Hervé Delingette

Statistical shape modeling is the computational process of discovering significant shape parameters from segmented anatomies captured by medical images (such as MRI and CT scans), which can fully describe subject-specific anatomy in the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Krithika Iyer , Shireen Elhabian

Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Jadie Adams , Shireen Elhabian

Solving inverse problems with the reverse process of a diffusion model represents an appealing avenue to produce highly realistic, yet diverse solutions from incomplete and possibly noisy measurements, ultimately enabling uncertainty…

Geophysics · Physics 2025-01-10 Matteo Ravasi

We propose a shape fitting/registration method based on a Gaussian Processes formulation, suitable for shapes with extensive regions of missing data. Gaussian Processes are a proven powerful tool, as they provide a unified setting for shape…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Filipa Valdeira , Ricardo Ferreira , Alessandra Micheletti , Cláudia Soares

The majority of these machines fabricate from raw material in powder form using a directed energy beam to create a local melt zone. Total hip replacement is recommended for people who have medical issues related to excessive wear of the…

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

The Gaussian process state space model (GPSSM) is a non-linear dynamical system, where unknown transition and/or measurement mappings are described by GPs. Most research in GPSSMs has focussed on the state estimation problem, i.e.,…

Machine Learning · Statistics 2017-11-08 Stefanos Eleftheriadis , Thomas F. W. Nicholson , Marc Peter Deisenroth , James Hensman

We present the \textit{hierarchical Dirichlet scaling process} (HDSP), a Bayesian nonparametric mixed membership model. The HDSP generalizes the hierarchical Dirichlet process (HDP) to model the correlation structure between metadata in the…

Machine Learning · Computer Science 2017-07-10 Dongwoo Kim , Alice Oh

Monitoring maternal and fetal health during pregnancy is crucial for preventing adverse outcomes. While tests such as ultrasound scans offer high accuracy, they can be costly and inconvenient. Telehealth and more accessible body shape…

Purpose: Trochlear Dysplasia (TD) is a common malformation in adolescents, leading to anterior knee pain and instability. Surgical interventions such as trochleoplasty require precise planning to correct the trochlear groove. However, no…

Image and Video Processing · Electrical Eng. & Systems 2024-12-16 Michael Wehrli , Alicia Durrer , Paul Friedrich , Volodimir Buchakchiyskiy , Marcus Mumme , Edwin Li , Gyozo Lehoczky , Carol C. Hasler , Philippe C. Cattin

Accurate prediction of anthropometric body composition variables, such as Appendicular Lean Mass (ALM), Body Fat Percentage (BFP), and Bone Mineral Density (BMD), is essential for early diagnosis of several chronic diseases. Currently,…

Clinical investigations of anatomy's structural changes over time could greatly benefit from population-level quantification of shape, or spatiotemporal statistic shape modeling (SSM). Such a tool enables characterizing patient organ cycles…

Machine Learning · Computer Science 2022-09-08 Jadie Adams , Nawazish Khan , Alan Morris , Shireen Elhabian

Diffusion models have shown strong performances in solving inverse problems through posterior sampling while they suffer from errors during earlier steps. To mitigate this issue, several Decoupled Posterior Sampling methods have been…

Machine Learning · Computer Science 2025-04-15 Zhi Qi , Shihong Yuan , Yulin Yuan , Linling Kuang , Yoshiyuki Kabashima , Xiangming Meng

Clinical patient records are an example of high-dimensional data that is typically collected from disparate sources and comprises of multiple likelihoods with noisy as well as missing values. In this work, we propose an unsupervised…

Machine Learning · Statistics 2021-04-21 Siddharth Ramchandran , Miika Koskinen , Harri Lähdesmäki

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

Abdominal aortic aneurysms (AAAs) are pathologic dilatations of the abdominal aorta posing a high fatality risk upon rupture. Studying AAA progression and rupture risk often involves in-silico blood flow modelling with computational fluid…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Patryk Rygiel , Julian Suk , Christoph Brune , Kak Khee Yeung , Jelmer M. Wolterink

Objective: ascending aortic aneurysm growth prediction is still challenging in clinics. In this study, we evaluate and compare the ability of local and global shape features to predict ascending aortic aneurysm growth. Material and methods:…

Diabetes is a serious chronic metabolic disease. In the recent years, more and more consumer technology enterprises focusing on human health are committed to implementing accurate and non-invasive blood glucose algorithm in their products.…

Machine Learning · Computer Science 2025-03-05 Yiting Wei , Bingo Wing-Kuen Ling , Qing Liu , Jiaxin Liu

Recent years have witnessed rapid advancements in 3D scanning technologies, with applications spanning VR/AR, digital human creation, and medical imaging. Structured-light scanning with phase-shifting techniques is preferred for its use of…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Xiang Gao , Xinmu Wang , Zhou Zhao , Junqi Huang , Xianfeng David Gu