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Although distributed lag non-linear models (DLNMs) are commonly used to quantify delayed and non-linear exposure-response relationships, most existing applications assume that these relationships are constant across space. However, in many…

Methodology · Statistics 2026-04-13 Sara Rutten , Thomas Neyens , Elisa Duarte , Antonio Gasparrini , Christel Faes

Distributed lag non-linear models (DLNMs) are a popular approach to flexibly model the effect of time-delayed exposures. Classical DLNMs specify a common exposure-lag-response relationship across geographical areas. However, this…

Methodology · Statistics 2026-03-20 Sara Rutten , Thomas Neyens , Elisa Duarte , Antonio Gasparrini , Christel Faes

In studies of maternal exposure to air pollution a children's health outcome is regressed on exposures observed during pregnancy. The distributed lag nonlinear model (DLNM) is a statistical method commonly implemented to estimate an…

Methodology · Statistics 2021-06-16 Daniel Mork , Ander Wilson

In environmental health research there is often interest in the effect of an exposure on a health outcome assessed on the same day and several subsequent days or lags. Distributed lag nonlinear models (DLNM) are a well-established…

Methodology · Statistics 2023-10-05 Daniel Mork , Ander Wilson

Environmental exposures, such as air pollution and extreme temperatures, have complex effects on human health. These effects are often characterized by non-linear exposure-lag-response relationships and delayed impacts over time. Accurately…

Methodology · Statistics 2025-12-02 Álvaro Briz-Redón , Ana Corberán-Vallet , Adina Iftimi , Carmen Íñiguez

Quantifying associations between short-term exposure to ambient air pollution and health outcomes is an important public health priority. Many studies have investigated the association considering delayed effects within the past few days.…

Methodology · Statistics 2025-05-22 Tianyi Pan , Hwashin Hyun Shin , Glen McGee , Alex Stringer

Distributed lag models (DLMs) express the cumulative and delayed dependence between pairs of time-indexed response and explanatory variables. In practical application, users of DLMs examine the estimated influence of a series of lagged…

Applications · Statistics 2018-01-23 Alastair Rushworth

Latent space models (LSMs) are often used to analyze dynamic (time-varying) networks that evolve in continuous time. Existing approaches to Bayesian inference for these models rely on Markov chain Monte Carlo algorithms, which cannot handle…

Methodology · Statistics 2024-01-19 Joshua Daniel Loyal

Generalized additive models (GAMs) are a well-established statistical tool for modeling complex nonlinear relationships between covariates and a response assumed to have a conditional distribution in the exponential family. In this article,…

Methodology · Statistics 2021-03-02 Oswaldo Gressani , Philippe Lambert

Laplacian-P-splines (LPS) associate the P-splines smoother and the Laplace approximation in a unifying framework for fast and flexible inference under the Bayesian paradigm. Gaussian Markov field priors imposed on penalized latent variables…

Methodology · Statistics 2023-09-18 Philippe Lambert , Oswaldo Gressani

Shared frailty models have been proposed to accommodate unmeasured cluster-specific risk factors through the inclusion of a common latent frailty term. Among possible frailty distributions, the Gamma distribution is appealing due to its…

Methodology · Statistics 2026-05-13 Piotr Lewczuk , Oswaldo Gressani , Steven Abrams , Christel Faes

When examining the relationship between an exposure and an outcome, there is often a time lag between exposure and the observed effect on the outcome. A common statistical approach for estimating the relationship between the outcome and…

Methodology · Statistics 2025-04-28 Seongwon Im , Ander Wilson , Daniel Mork

The mixture cure model for analyzing survival data is characterized by the assumption that the population under study is divided into a group of subjects who will experience the event of interest over some finite time horizon and another…

Methodology · Statistics 2022-03-30 Oswaldo Gressani , Christel Faes , Niel Hens

We present a novel Bayesian spatial disaggregation model for count data, providing fast and flexible inference at high resolution. First, it incorporates non-linear covariate effects using penalized splines, a flexible approach that is not…

Methodology · Statistics 2026-04-13 Sara Rutten , Thomas Neyens , Elisa Duarte , Christel Faes

Latent Class Models (LCMs) are used to cluster multivariate categorical data (e.g. group participants based on survey responses). Traditional LCMs assume a property called conditional independence. This assumption can be restrictive,…

Machine Learning · Statistics 2024-06-19 Jesse Bowers , Steve Culpepper

This study quantifies the association between air pollution and mortality in Ontario, Canada. Exposure-response relationships in air pollution epidemiology are complex due to three features: time-lagged associations, non-linear…

Methodology · Statistics 2026-04-27 Tianyi Pan , Hwashin Hyun Shin , Alex Stringer , Glen McGee

Distributed Lag Models (DLMs) and similar regression approaches such as MIDAS have been used for many decades in econometrics and more recently to investigate how poor air quality adversely affects human health. In this paper we describe…

Methodology · Statistics 2025-01-30 Daniel Dempsey , Jason Wyse

In recent years, spatial and spatio-temporal modeling have become an important area of research in many fields (epidemiology, environmental studies, disease mapping). In this work we propose different spatial models to study hospital…

Applications · Statistics 2010-06-21 Erik A. Sauleau , Valentina Mameli , Monica Musio

Quantifying spatial and/or temporal associations in multivariate geolocated data of different types is achievable via spatial random effects in a Bayesian hierarchical model, but severe computational bottlenecks arise when spatial…

Methodology · Statistics 2024-04-02 Michele Peruzzi , David B. Dunson

A new dynamic latent space eigenmodel (LSM) is proposed for weighted temporal networks. The model accommodates integer-valued weights, excess of zeros, time-varying node positions (features), and time-varying network sparsity. The latent…

Methodology · Statistics 2026-04-15 Roberto Casarin , Matteo Iacopini , Antonio Peruzzi
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