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Medical anomaly detection has emerged as a promising solution to challenges in data availability and labeling constraints. Traditional methods extract features from different layers of pre-trained networks in Euclidean space; however,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Alvaro Gonzalez-Jimenez , Simone Lionetti , Ludovic Amruthalingam , Philippe Gottfrois , Fabian Gröger , Marc Pouly , Alexander A. Navarini

With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

The recent availability of large datasets in bio-medicine has inspired the development of representation learning methods for multiple healthcare applications. Despite advances in predictive performance, the clinical utility of such methods…

Signal Processing · Electrical Eng. & Systems 2022-10-18 Neeraj Wagh , Jionghao Wei , Samarth Rawal , Brent M. Berry , Yogatheesan Varatharajah

Latent space models are powerful statistical tools for modeling and understanding network data. While the importance of accounting for uncertainty in network analysis has been well recognized, the current literature predominantly focuses on…

Statistics Theory · Mathematics 2025-08-15 Jinming Li , Shihao Wu , Chengyu Cui , Gongjun Xu , Ji Zhu

Neural models learn data representations that lie on low-dimensional manifolds, yet modeling the relation between these representational spaces is an ongoing challenge. By integrating spectral geometry principles into neural modeling, we…

Machine Learning · Computer Science 2025-07-15 Marco Fumero , Marco Pegoraro , Valentino Maiorca , Francesco Locatello , Emanuele Rodolà

The shape of an object is an important characteristic for many vision problems such as segmentation, detection and tracking. Being independent of appearance, it is possible to generalize to a large range of objects from only small amounts…

Machine Learning · Statistics 2018-12-14 Alessandro Di Martino , Erik Bodin , Carl Henrik Ek , Neill D. F. Campbell

In many applications, data can be heterogeneous in the sense of spanning latent groups with different underlying distributions. When predictive models are applied to such data the heterogeneity can affect both predictive performance and…

Machine Learning · Statistics 2022-05-04 Thomas Lartigue , Sach Mukherjee

We introduce a representation learning framework for spatial trajectories. We represent partial observations of trajectories as probability distributions in a learned latent space, which characterize the uncertainty about unobserved parts…

Machine Learning · Computer Science 2022-10-05 Dídac Surís , Carl Vondrick

Disentangled representation learning has been proposed as an approach to learning general representations even in the absence of, or with limited, supervision. A good general representation can be fine-tuned for new target tasks using…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Xiao Liu , Pedro Sanchez , Spyridon Thermos , Alison Q. O'Neil , Sotirios A. Tsaftaris

Latent space models are frequently used for modeling single-layer networks and include many popular special cases, such as the stochastic block model and the random dot product graph. However, they are not well-developed for more complex…

Methodology · Statistics 2021-07-09 Peter W. MacDonald , Elizaveta Levina , Ji Zhu

Medical time series are often irregular and face significant missingness, posing challenges for data analysis and clinical decision-making. Existing methods typically adopt a single modeling perspective, either treating series data as…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Liuqing Chen , Shuhong Xiao , Shixian Ding , Shanhai Hu , Lingyun Sun

There is a large ongoing scientific effort in mechanistic interpretability to map embeddings and internal representations of AI systems into human-understandable concepts. A key element of this effort is the linear representation…

Machine Learning · Computer Science 2025-05-27 Alexander Modell , Patrick Rubin-Delanchy , Nick Whiteley

Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Julian Schön , Raghavendra Selvan , Lotte Nygård , Ivan Richter Vogelius , Jens Petersen

Identifying new disease-related patterns in medical imaging data with the help of machine learning enlarges the vocabulary of recognizable findings. This supports diagnostic and prognostic assessment. However, image appearance varies not…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Jeanny Pan , Philipp Seeböck , Christoph Fürböck , Svitlana Pochepnia , Jennifer Straub , Lucian Beer , Helmut Prosch , Georg Langs

Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

Interpretation of medical images for diagnosis and treatment of complex disease from high-dimensional and heterogeneous data remains a key challenge in transforming healthcare. In the last few years, both supervised and unsupervised deep…

Image and Video Processing · Electrical Eng. & Systems 2018-12-20 Khalid Raza , Nripendra Kumar Singh

We propose a novel shape representation useful for analyzing and processing shape collections, as well for a variety of learning and inference tasks. Unlike most approaches that capture variability in a collection by using a template model…

Graphics · Computer Science 2018-06-13 Ruqi Huang , Panos Achlioptas , Leonidas Guibas , Maks Ovsjanikov

Large longitudinal studies provide lots of valuable information, especially in medical applications. A problem which must be taken care of in order to utilize their full potential is that of correlation between intra-subject measurements…

Methodology · Statistics 2022-02-14 Martin Hanik , Hans-Christian Hege , Christoph von Tycowicz

This work describes a novel data-driven latent space inference framework built on paired autoencoders to handle observational inconsistencies when solving inverse problems. Our approach uses two autoencoders, one for the parameter space and…

Machine Learning · Computer Science 2026-01-19 Emma Hart , Bas Peters , Julianne Chung , Matthias Chung

With the expeditious advancement of information technologies, health-related data presented unprecedented potentials for medical and health discoveries but at the same time significant challenges for machine learning techniques both in…

Machine Learning · Computer Science 2018-11-05 Shuo Yang