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Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Millions of individuals' well-being are challenged by the harms of substance use. Harm reduction as a public health strategy is designed to improve their health outcomes and reduce safety risks. Some large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-30 Kaixuan Wang , Chenxin Diao , Jason T. Jacques , Zhongliang Guo , Shuai Zhao

Numeral systems and units of measurement are two conjoined topics in activities of human beings and have mutual effects with the languages expressing them. Currently, the evaluation of Large Language Models (LLMs) often involves…

Computation and Language · Computer Science 2024-06-06 Ancheng Xu , Minghuan Tan , Lei Wang , Min Yang , Ruifeng Xu

The use of large language models (LLMs) for qualitative analysis is gaining attention in various fields, including software engineering, where qualitative methods are essential for understanding human and social factors. This study aimed to…

Software Engineering · Computer Science 2025-03-11 Matheus de Morais Leça , Lucas Valença , Reydne Santos , Ronnie de Souza Santos

Large language models (LLMs) have shown their potential in biomedical fields. However, how the public uses them for healthcare purposes such as medical Q\&A, self-diagnosis, and daily healthcare information seeking is under-investigated.…

Computers and Society · Computer Science 2024-09-13 Yunpeng Xiao , Kyrie Zhixuan Zhou , Yueqing Liang , Kai Shu

Large Language Models (LLMs) are increasingly employed for simulating human behaviors across diverse domains. However, our position is that current LLM-based human simulations remain insufficiently reliable, as evidenced by significant…

Computation and Language · Computer Science 2025-12-02 Qian Wang , Jiaying Wu , Zichen Jiang , Zhenheng Tang , Bingqiao Luo , Nuo Chen , Wei Chen , Bingsheng He

Large language models (LLMs) have been applied to tasks in healthcare, ranging from medical exam questions to responding to patient questions. With increasing institutional partnerships between companies producing LLMs and healthcare…

Computation and Language · Computer Science 2024-04-10 Jesutofunmi A. Omiye , Haiwen Gui , Shawheen J. Rezaei , James Zou , Roxana Daneshjou

Evaluating natural language generation (NLG) systems remains a core challenge of natural language processing (NLP), further complicated by the rise of large language models (LLMs) that aims to be general-purpose. Recently, large language…

Computation and Language · Computer Science 2025-08-29 Khaoula Chehbouni , Mohammed Haddou , Jackie Chi Kit Cheung , Golnoosh Farnadi

The humanlike responses of large language models (LLMs) have prompted social scientists to investigate whether LLMs can be used to simulate human participants in experiments, opinion polls and surveys. Of central interest in this line of…

Computation and Language · Computer Science 2024-05-14 Nikolay B Petrov , Gregory Serapio-García , Jason Rentfrow

Large Language Models (LLMs) excel in handling general knowledge tasks, yet they struggle with user-specific personalization, such as understanding individual emotions, writing styles, and preferences. Personalized Large Language Models…

Artificial Intelligence · Computer Science 2025-09-23 Jiahong Liu , Zexuan Qiu , Zhongyang Li , Quanyu Dai , Wenhao Yu , Jieming Zhu , Minda Hu , Menglin Yang , Tat-Seng Chua , Irwin King

Large language models (LLMs) are being increasingly integrated into legal applications, including judicial decision support, legal practice assistance, and public-facing legal services. While LLMs show strong potential in handling legal…

Although Large Language Models (LLMs) have shown promising performance in healthcare-related applications, their deployment in the medical domain poses unique challenges of ethical, regulatory, and technical nature. In this study, we employ…

Computers and Society · Computer Science 2025-01-22 Giorgia Carra , Bogdan Kulynych , François Bastardot , Daniel E. Kaufmann , Noémie Boillat-Blanco , Jean Louis Raisaro

The introduction of large language models (LLMs) has greatly enhanced the capabilities of software agents. Instead of relying on rule-based interactions, agents can now interact in flexible ways akin to humans. However, this flexibility…

Human-Computer Interaction · Computer Science 2026-02-04 Joar Sabel , Mattias Wingren , Andreas Lundell , Sören Andersson , Sara Rosenberg , Susanne Hägglund , Linda Estman , Malin Andtfolk

The pursuit of leaderboard rankings in Large Language Models (LLMs) has created a fundamental paradox: models excel at standardized tests while failing to demonstrate genuine language understanding and adaptability. Our systematic analysis…

Computation and Language · Computer Science 2024-12-06 Sourav Banerjee , Ayushi Agarwal , Eishkaran Singh

This paper examines the opportunities, limitations, and practical considerations associated with the use of large language models (LLMs) in qualitative research. Drawing on a multidisciplinary perspective that combines expertise in…

Human-Computer Interaction · Computer Science 2026-05-19 Henry Salgado , Meagan R. Kendall , Martine Ceberio , Alexandra Coso Strong

Large Language Models (LLMs) are transforming writing, reading, teaching, and knowledge retrieval in many academic fields. However, concerns regarding their misuse and erroneous outputs have led to varying degrees of trust in LLMs within…

Computers and Society · Computer Science 2025-02-10 Minseok Jung , Aurora Zhang , May Fung , Junho Lee , Paul Pu Liang

Large language models (LLMs) have enabled a range of applications in zero-shot and few-shot learning settings, including the generation of synthetic datasets for training and testing. However, to reliably use these synthetic datasets, it is…

Computation and Language · Computer Science 2024-09-19 Gaurav Maheshwari , Dmitry Ivanov , Kevin El Haddad

Understanding the similarity of the numerous released large language models (LLMs) has many uses, e.g., simplifying model selection, detecting illegal model reuse, and advancing our understanding of what makes LLMs perform well. In this…

Machine Learning · Computer Science 2023-12-06 Max Klabunde , Mehdi Ben Amor , Michael Granitzer , Florian Lemmerich

Standardized math assessments require expensive human pilot studies to establish the difficulty of test items. We investigate the predictive value of open-source large language models (LLMs) for evaluating the difficulty of multiple-choice…

Computation and Language · Computer Science 2026-04-22 Christabel Acquaye , Yi Ting Huang , Marine Carpuat , Rachel Rudinger

[Context] Large Language Models (LLMs) are increasingly used to assist qualitative research in Software Engineering (SE), yet the methodological implications of this usage remain underexplored. Their integration into interpretive processes…

Software Engineering · Computer Science 2025-11-19 Tatiane Ornelas , Allysson Allex Araújo , Júlia Araújo , Marina Araújo , Bianca Trinkenreich , Marcos Kalinowski