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Concept-based explanations permit to understand the predictions of a deep neural network (DNN) through the lens of concepts specified by users. Existing methods assume that the examples illustrating a concept are mapped in a fixed direction…

Machine Learning · Computer Science 2022-09-30 Jonathan Crabbé , Mihaela van der Schaar

Lack of explainability in artificial intelligence, specifically deep neural networks, remains a bottleneck for implementing models in practice. Popular techniques such as Gradient-weighted Class Activation Mapping (Grad-CAM) provide a…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Amil Dravid , Aggelos K. Katsaggelos

Interpreting the inner workings of deep learning models is crucial for establishing trust and ensuring model safety. Concept-based explanations have emerged as a superior approach that is more interpretable than feature attribution…

Machine Learning · Computer Science 2023-07-17 Mara Graziani , Laura O' Mahony , An-Phi Nguyen , Henning Müller , Vincent Andrearczyk

Causal generative modelling is gaining interest in medical imaging due to its ability to answer interventional and counterfactual queries. Most work focuses on generating counterfactual images that look plausible, using auxiliary…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Tian Xia , Mélanie Roschewitz , Fabio De Sousa Ribeiro , Charles Jones , Ben Glocker

Concept Activation Vectors (CAVs) provide a powerful approach for interpreting deep neural networks by quantifying their sensitivity to human-defined concepts. However, when computed independently at different layers, CAVs often exhibit…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhenghao He , Sanchit Sinha , Guangzhi Xiong , Aidong Zhang

Counterfactual explanations enhance the interpretability of deep learning models in medical imaging, yet adapting them to 3D CT scans poses challenges due to volumetric complexity and resource demands. We extend the Latent Shift…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Joseph Paul Cohen , Louis Blankemeier , Akshay Chaudhari

Despite their high accuracies, modern complex image classifiers cannot be trusted for sensitive tasks due to their unknown decision-making process and potential biases. Counterfactual explanations are very effective in providing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-13 Kamran Alipour , Aditya Lahiri , Ehsan Adeli , Babak Salimi , Michael Pazzani

Interpretability and small labelled datasets are key issues in the practical application of deep learning, particularly in areas such as medicine. In this paper, we present a semi-supervised technique that addresses both these issues by…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Jarrel Seah , Jennifer Tang , Andy Kitchen , Jonathan Seah

We present a novel framework for explainable labeling and interpretation of medical images. Medical images require specialized professionals for interpretation, and are explained (typically) via elaborate textual reports. Different from…

Image and Video Processing · Electrical Eng. & Systems 2022-11-17 Dwarikanath Mahapatra

Concept Bottleneck Models (CBMs) in medical imaging aim to improve model interpretability by predicting intermediate clinical concepts before final diagnoses. However, most existing CBMs treat concepts as discriminative predictors of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Interpretability methods for image classification assess model trustworthiness by attempting to expose whether the model is systematically biased or attending to the same cues as a human would. Saliency methods for feature attribution…

Machine Learning · Statistics 2021-04-08 Jacob Pfau , Albert T. Young , Jerome Wei , Maria L. Wei , Michael J. Keiser

Generative models such as Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs) play an increasingly important role in medical image analysis. The latent spaces of these models often show semantically meaningful…

Image and Video Processing · Electrical Eng. & Systems 2022-07-21 Julian Schön , Raghavendra Selvan , Jens Petersen

Segmenting anatomical structures in medical images plays an important role in the quantitative assessment of various diseases. However, accurate segmentation becomes significantly more challenging in the presence of disease. Disease…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Raghav Mehta , Fabio De Sousa Ribeiro , Tian Xia , Melanie Roschewitz , Ainkaran Santhirasekaram , Dominic C. Marshall , Ben Glocker

Convolutional neural network (CNN) models for computer vision are powerful but lack explainability in their most basic form. This deficiency remains a key challenge when applying CNNs in important domains. Recent work on explanations…

Computer Vision and Pattern Recognition · Computer Science 2021-06-18 Ruihan Zhang , Prashan Madumal , Tim Miller , Krista A. Ehinger , Benjamin I. P. Rubinstein

Counterfactual medical image generation enables clinicians to explore clinical hypotheses, such as predicting disease progression, facilitating their decision-making. While existing methods can generate visually plausible images from…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Chenglong Ma , Yuanfeng Ji , Jin Ye , Lu Zhang , Ying Chen , Tianbin Li , Mingjie Li , Junjun He , Hongming Shan

To interpret deep learning models, one mainstream is to explore the learned concepts by networks. Testing with Concept Activation Vector (TCAV) presents a powerful tool to quantify the contribution of query concepts (represented by…

Computer Vision and Pattern Recognition · Computer Science 2022-05-25 Andong Wang , Wei-Ning Lee

Counterfactual explanations (CEs) aim to enhance the interpretability of machine learning models by illustrating how alterations in input features would affect the resulting predictions. Common CE approaches require an additional model and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Matan Atad , David Schinz , Hendrik Moeller , Robert Graf , Benedikt Wiestler , Daniel Rueckert , Nassir Navab , Jan S. Kirschke , Matthias Keicher

Deep learning has advanced medical image classification, but interpretability challenges hinder its clinical adoption. This study enhances interpretability in Chest X-ray (CXR) classification by using concept bottleneck models (CBMs) and a…

Information Retrieval · Computer Science 2025-04-30 Hasan Md Tusfiqur Alam , Devansh Srivastav , Md Abdul Kadir , Daniel Sonntag

Artificial intelligence is increasingly leveraged across various domains to automate decision-making processes that significantly impact human lives. In medical image analysis, deep learning models have demonstrated remarkable performance.…

Machine Learning · Computer Science 2025-07-28 Julia Siekiera , Stefan Kramer

As large language models (LLMs) are widely deployed across various domains, the ability to control their generated outputs has become more critical. This control involves aligning LLMs outputs with human values and ethical principles or…

Computation and Language · Computer Science 2025-01-13 Hanyu Zhang , Xiting Wang , Chengao Li , Xiang Ao , Qing He