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Healthcare conversational AI agents shouldn't be optimized only for clean benchmark accuracy in production-first regime; they must be optimized for the lived reality of patient conversations, where audio is imperfect, intent is indirect,…

Traditional AI-based healthcare systems often rely on single-modal data, limiting diagnostic accuracy due to incomplete information. However, recent advancements in foundation models show promising potential for enhancing diagnosis…

Artificial Intelligence · Computer Science 2025-03-24 Sihan Wang , Suiyang Jiang , Yibo Gao , Boming Wang , Shangqi Gao , Xiahai Zhuang

Simulating dementia patients with large language models (LLMs) is challenging due to the need to jointly model cognitive impairment, emotional dynamics, and nonverbal behaviors over long conversations. We present DemMA, an expert-guided…

Multiagent Systems · Computer Science 2026-01-13 Yutong Song , Jiang Wu , Kazi Sharif , Honghui Xu , Nikil Dutt , Amir Rahmani

The recent shift toward the Health Level Seven Fast Healthcare Interoperability Resources (HL7 FHIR) standard opens a new frontier for clinical AI, demanding LLM agents to navigate complex, resource-based data models instead of conventional…

Computation and Language · Computer Science 2025-11-14 Gyubok Lee , Elea Bach , Eric Yang , Tom Pollard , Alistair Johnson , Edward Choi , Yugang jia , Jong Ha Lee

The deployment of AI models in clinical practice faces a critical challenge: models achieving expert-level performance on benchmarks can fail catastrophically when confronted with real-world variations in medical imaging. Minor shifts in…

Artificial Intelligence · Computer Science 2025-07-09 Lukas Kuhn , Florian Buettner

Online, people often recount their experiences turning to conversational AI agents (e.g., ChatGPT, Claude, Copilot) for mental health support -- going so far as to replace their therapists. These anecdotes suggest that AI agents have great…

Modeling & Simulation (M&S) approaches such as agent-based models hold significant potential to support decision-making activities in health, with recent examples including the adoption of vaccines, and a vast literature on healthy eating…

Artificial Intelligence · Computer Science 2025-09-08 Philippe J. Giabbanelli , Ameeta Agrawal

Although artificial intelligence (AI) agents are increasingly proposed to support potentially longitudinal health tasks, such as symptom management, behavior change, and patient support, most current implementations fall short of…

Artificial Intelligence · Computer Science 2026-04-30 Georgianna Lin , Rencong Jiang , Noémie Elhadad , Xuhai "Orson" Xu

Simulating consumer decision-making is vital for designing and evaluating marketing strategies before costly real-world deployment. However, post-event analyses and rule-based agent-based models (ABMs) struggle to capture the complexity of…

Artificial Intelligence · Computer Science 2025-10-22 Man-Lin Chu , Lucian Terhorst , Kadin Reed , Tom Ni , Weiwei Chen , Rongyu Lin

The believable simulation of multi-user behavior is crucial for understanding complex social systems. Recently, large language models (LLMs)-based AI agents have made significant progress, enabling them to achieve human-like intelligence…

Artificial Intelligence · Computer Science 2024-12-16 Yijun Liu , Wu Liu , Xiaoyan Gu , Yong Rui , Xiaodong He , Yongdong Zhang

Couples therapy requires managing complex, evolving emotional dynamics between partners, but traditional training methods for therapists, like role-play, lack realism, consistency, and control. We present a multi-modal simulation that…

Computers and Society · Computer Science 2026-04-06 Canwen Wang , Angela Chen , Catherine Bao , Siwei Jin , Holly Swartz , Tongshuang Wu , Robert E Kraut , Haiyi Zhu

The rise of Large Language Models (LLMs) has enabled the development of specialized AI agents with domain-specific reasoning and interaction capabilities, particularly in healthcare. While recent frameworks simulate medical decision-making,…

Artificial Intelligence · Computer Science 2025-07-04 Tianqi Shang , Weiqing He , Charles Zheng , Lingyao Li , Li Shen , Bingxin Zhao

Progress toward Artificial General Intelligence (AGI) faces significant bottlenecks, particularly in rigorously evaluating complex interactive systems and acquiring the vast interaction data needed for training adaptive agents. This paper…

Artificial Intelligence · Computer Science 2025-09-25 Krisztian Balog , ChengXiang Zhai

In the domain of Human-Computer Interaction, focus groups represent a widely utilised yet resource-intensive methodology, often demanding the expertise of skilled moderators and meticulous preparatory efforts. This study introduces the…

Human-Computer Interaction · Computer Science 2024-09-04 Taiyu Zhang , Xuesong Zhang , Robbe Cools , Adalberto L. Simeone

LLM-based user simulation is the primary mechanism for end-to-end agent evaluation, yet simulated users are poor proxies for real humans: unconstrained LLM defaults produce a Formalism Ceiling (style match rates of 6-8% against real users),…

Human-Computer Interaction · Computer Science 2026-05-21 Ming Zhu , Juntao Tan , Rithesh Murthy , Jielin Qiu , Liangwei Yang , Wenting Zhao , Silvio Savarese , Shelby Heinecke , Huan Wang

This study introduces a transformative framework for medical education by integrating semi-structured data with Large Language Models (LLMs), primarily OpenAIs ChatGPT3.5, to automate the creation of medical simulation scenarios.…

Computation and Language · Computer Science 2024-05-07 Scott Sumpter

Recommender systems play a central role in numerous real-life applications, yet evaluating their performance remains a significant challenge due to the gap between offline metrics and online behaviors. Given the scarcity and limits (e.g.,…

Information Retrieval · Computer Science 2025-04-18 Nicolas Bougie , Narimasa Watanabe

Virtual Mental Health Assistants (VMHAs) are seeing continual advancements to support the overburdened global healthcare system that gets 60 million primary care visits, and 6 million Emergency Room (ER) visits annually. These systems are…

Artificial Intelligence · Computer Science 2023-04-27 Surjodeep Sarkar , Manas Gaur , L. Chen , Muskan Garg , Biplav Srivastava , Bhaktee Dongaonkar

Medical education faces challenges in providing scalable, consistent clinical skills training. Simulation with standardized patients (SPs) develops communication and diagnostic skills but remains resource-intensive and variable in feedback…

Traditionally, AI research in medical diagnosis has largely centered on image analysis. While this has led to notable advancements, the absence of patient-reported symptoms continues to hinder diagnostic accuracy. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 K Lokesh , Abhirama Subramanyam Penamakuri , Uday Agarwal , Apoorva Challa , Shreya K Gowda , Somesh Gupta , Anand Mishra
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