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We present Doctorina MedBench, a comprehensive evaluation framework for agent-based medical AI based on the simulation of realistic physician-patient interactions. Unlike traditional medical benchmarks that rely on solving standardized test…

Computation and Language · Computer Science 2026-03-30 Anna Kozlova , Stanislau Salavei , Pavel Satalkin , Hanna Plotnitskaya , Sergey Parfenyuk

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

User simulation is a promising approach for automatically training and evaluating conversational information access agents, enabling the generation of synthetic dialogues and facilitating reproducible experiments at scale. However, the…

Information Retrieval · Computer Science 2024-06-28 Nolwenn Bernard , Krisztian Balog

We present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn interactive diagnostic processes, adaptively select examinations, and commit to final…

Computation and Language · Computer Science 2026-02-11 Pengcheng Qiu , Chaoyi Wu , Junwei Liu , Qiaoyu Zheng , Yusheng Liao , Haowen Wang , Yun Yue , Qianrui Fan , Shuai Zhen , Jian Wang , Jinjie Gu , Yanfeng Wang , Ya Zhang , Weidi Xie

We introduce a novel application of large language models (LLMs) in developing a virtual counselor capable of conducting motivational interviewing (MI) for alcohol use counseling. Access to effective counseling remains limited, particularly…

Human-Computer Interaction · Computer Science 2024-07-12 Ian Steenstra , Farnaz Nouraei , Mehdi Arjmand , Timothy W. Bickmore

Recently, large language models have shown great potential to transform online medical consultation. Despite this, most research targets improving diagnostic accuracy with ample information, often overlooking the inquiry phase. Some studies…

Computation and Language · Computer Science 2025-03-12 Zhaocheng Liu , Quan Tu , Wen Ye , Yu Xiao , Zhishou Zhang , Hengfu Cui , Yalun Zhu , Qiang Ju , Shizheng Li , Jian Xie

Task-oriented conversational systems are essential for efficiently addressing diverse user needs, yet their development requires substantial amounts of high-quality conversational data that is challenging and costly to obtain. While large…

Information Retrieval · Computer Science 2025-11-06 Zhefan Wang , Ning Geng , Zhiqiang Guo , Weizhi Ma , Min Zhang

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study…

Computation and Language · Computer Science 2024-05-14 Yu He Ke , Rui Yang , Sui An Lie , Taylor Xin Yi Lim , Hairil Rizal Abdullah , Daniel Shu Wei Ting , Nan Liu

Evaluating recommender systems remains challenging due to the gap between offline metrics and real user behavior, as well as the scarcity of interaction data. Recent work explores large language model (LLM) agents as synthetic users, yet…

Information Retrieval · Computer Science 2026-01-06 Nicolas Bougie , Gian Maria Marconi , Tony Yip , Narimasa Watanabe

Recent advances in large language models (LLMs) have enabled new possibilities in simulating complex physiological systems. We introduce Organ-Agents, a multi-agent framework that simulates human physiology via LLM-driven agents. Each…

Effective dementia caregiving requires training and adaptive communication, but assistive AI and robotics are constrained by a lack of context-rich, privacy-sensitive data on how people living with Alzheimer's disease and related dementias…

Human-Computer Interaction · Computer Science 2026-04-01 Kruthika Gangaraju , Shu-Fen Wung , Kevin Berner , Jing Wang , Fengpei Yuan

At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

User simulation is an emerging interdisciplinary topic with multiple critical applications in the era of Generative AI. It involves creating an intelligent agent that mimics the actions of a human user interacting with an AI system,…

Artificial Intelligence · Computer Science 2026-04-22 Krisztian Balog , ChengXiang Zhai

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

The promise of AI in medicine depends on learning from data that reflect what matters to patients and clinicians. Most existing models are trained on electronic health records (EHRs), which capture biological measures but rarely…

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

Recent advancements in the field of AI agents have impacted the way we work, enabling greater automation and collaboration between humans and agents. In the data visualization field, multi-agent systems can be useful for employing agents…

Artificial Intelligence · Computer Science 2025-09-03 Anton Wolter , Georgios Vidalakis , Michael Yu , Ankit Grover , Vaishali Dhanoa

The integration of voice-based AI agents in healthcare presents a transformative opportunity to bridge economic and accessibility gaps in digital health delivery. This paper explores the role of large language model (LLM)-powered voice…

Artificial Intelligence · Computer Science 2025-07-28 Bo Wen , Chen Wang , Qiwei Han , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Jeffrey L. Rogers

Early diagnosis of Alzheimer's disease and related dementias (ADRD) is critical for timely intervention, yet most diagnoses are delayed until advanced stages. While comprehensive patient narratives are essential for accurate diagnosis,…

Human-Computer Interaction · Computer Science 2026-01-28 Andrew G. Breithaupt , Nayoung Choi , James D. Finch , Jeanne M. Powell , Arin L. Nelson , Oz A. Alon , Howard J. Rosen , Jinho D. Choi

Robotic ultrasound systems can enhance medical diagnostics, but patient acceptance is a challenge. We propose a system combining an AI-powered conversational virtual agent with three mixed reality visualizations to improve trust and…

Human-Computer Interaction · Computer Science 2025-07-18 Tianyu Song , Felix Pabst , Ulrich Eck , Nassir Navab