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Inpatient pathways demand complex clinical decision-making based on comprehensive patient information, posing critical challenges for clinicians. Despite advancements in large language models (LLMs) in medical applications, limited research…

Artificial Intelligence · Computer Science 2025-03-18 Zhen Chen , Zhihao Peng , Xusheng Liang , Cheng Wang , Peigan Liang , Linsheng Zeng , Minjie Ju , Yixuan Yuan

As large language models (LLMs) are increasingly deployed in healthcare, ensuring their safety, particularly within collaborative multi-agent configurations, is paramount. In this paper we introduce MedSentry, a benchmark comprising 5 000…

Multiagent Systems · Computer Science 2025-05-28 Kai Chen , Taihang Zhen , Hewei Wang , Kailai Liu , Xinfeng Li , Jing Huo , Tianpei Yang , Jinfeng Xu , Wei Dong , Yang Gao

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

Agentic AI systems are increasingly capable of autonomous data science workflows, yet clinical prediction tasks demand domain expertise that purely automated approaches struggle to provide. We investigate how human guidance of agentic AI…

Identifying novel hypotheses is essential to scientific research, yet this process risks being overwhelmed by the sheer volume and complexity of available information. Existing automated methods often struggle to generate novel and…

One challenge for dialogue agents is recognizing feelings in the conversation partner and replying accordingly, a key communicative skill. While it is straightforward for humans to recognize and acknowledge others' feelings in a…

Computation and Language · Computer Science 2019-08-30 Hannah Rashkin , Eric Michael Smith , Margaret Li , Y-Lan Boureau

Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

Identifying associations between imaging phenotypes, disease risk factors, and clinical outcomes is essential for understanding disease mechanisms. However, traditional approaches rely on human-driven hypothesis testing and selection of…

Artificial Intelligence · Computer Science 2025-09-09 Weitong Zhang , Mengyun Qiao , Chengqi Zang , Steven Niederer , Paul M Matthews , Wenjia Bai , Bernhard Kainz

Large language model (LLM)-based agents are increasingly used to solve complex tasks involving tool use, such as web browsing, code execution, and data analysis. However, current evaluation benchmarks do not adequately assess their ability…

In this work, we introduce MedAgentSim, an open-source simulated clinical environment with doctor, patient, and measurement agents designed to evaluate and enhance LLM performance in dynamic diagnostic settings. Unlike prior approaches, our…

Computation and Language · Computer Science 2025-10-02 Mohammad Almansoori , Komal Kumar , Hisham Cholakkal

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Existing methods for AI psychological counselors predominantly rely on supervised fine-tuning using static dialogue datasets. However, this contrasts with human experts, who continuously refine their proficiency through clinical practice…

Artificial Intelligence · Computer Science 2026-04-29 Yutao Yang , Junsong Li , Qianjun Pan , Jie Zhou , Kai Chen , Qin Chen , Jingyuan Zhao , Ningning Zhou , Xin Li , Liang He

Mental health issues are worsening in today's competitive society, such as depression and anxiety. Traditional healings like counseling and chatbots fail to engage effectively, they often provide generic responses lacking emotional depth.…

Computation and Language · Computer Science 2025-09-12 Yujia Chen , Changsong Li , Yiming Wang , Tianjie Ju , Qingqing Xiao , Nan Zhang , Zifan Kong , Peng Wang , Binyu Yan

Objective: This paper introduces a patient simulator for scalable, automated evaluation of healthcare conversational agents, generating realistic, controllable interactions that systematically vary across medical, linguistic, and behavioral…

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of…

Applications · Statistics 2025-07-22 Eleonora Vitanza , Pietro DeLellis , Chiara Mocenni , Manuel Ruiz Marin

Single subject prediction of brain disorders from neuroimaging data has gained increasing attention in recent years. Yet, for some heterogeneous disorders such as major depression disorder (MDD) and autism spectrum disorder (ASD), the…

Machine Learning · Computer Science 2022-06-08 Ahmed El Gazzar , Rajat Mani Thomas , Guido Van Wingen

Social agents and robots are increasingly being used in wellbeing settings. However, a key challenge is that these agents and robots typically rely on machine learning (ML) algorithms to detect and analyse an individual's mental wellbeing.…

Machine Learning · Computer Science 2024-08-09 Joseph Cameron , Jiaee Cheong , Micol Spitale , Hatice Gunes

Dermatological diagnosis requires integrating fine-grained visual perception with expert clinical knowledge. Although Multimodal Large Language Models (MLLMs) facilitate interactive medical image analysis, their application in dermatology…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Yize Liu , Siyuan Yan , Ming Hu , Lie Ju , Xieji Li , Feilong Tang , Wei Feng , Zongyuan Ge

This study harnesses state-of-the-art AI technology for detecting mental disorders through user-generated textual content. Existing studies typically rely on fully supervised machine learning, which presents challenges such as the…

Computation and Language · Computer Science 2025-03-17 Haoxin Liu , Wenli Zhang , Jiaheng Xie , Buomsoo Kim , Zhu Zhang , Yidong Chai , Sudha Ram

Understanding human mental states from natural behavior is crucial for intelligent systems in the real world. However, most current research focuses on predicting isolated mental state labels, lacking structured annotations of complex…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Xiaoyu Yuan , Niklas Heikkala , Tiina Törmänen , Hanna Järvenoja , Guoying Zhao , Haoyu Chen