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This paper introduces DeepPsy-Agent, an innovative psychological support system that combines the three-stage helping theory in psychology with deep learning techniques. The system consists of two core components: (1) a multi-stage…

Artificial Intelligence · Computer Science 2025-03-21 Kai Chen , Zebing Sun

Artificial intelligence has shown promise in medical imaging, yet most existing systems lack flexibility, interpretability, and adaptability - challenges especially pronounced in ophthalmology, where diverse imaging modalities are…

This study introduces 'Psycho Analyst', a custom GPT model based on OpenAI's GPT-4, optimized for pre-screening mental health disorders. Enhanced with DSM-5, PHQ-8, detailed data descriptions, and extensive training data, the model adeptly…

Computers and Society · Computer Science 2025-01-28 Jinwen Tang , Yi Shang

Anxiety and depression are the most common mental health issues worldwide, affecting a non-negligible part of the population. Accordingly, stakeholders, including governments' health systems, are developing new strategies to promote early…

Artificial Intelligence · Computer Science 2024-12-24 Francisco de Arriba-Pérez , Silvia García-Méndez

Diagnosing diseases through histopathology whole slide images (WSIs) is fundamental in modern pathology but is challenged by the gigapixel scale and complexity of WSIs. Trained histopathologists overcome this challenge by navigating the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Fatemeh Ghezloo , Mehmet Saygin Seyfioglu , Rustin Soraki , Wisdom O. Ikezogwo , Beibin Li , Tejoram Vivekanandan , Joann G. Elmore , Ranjay Krishna , Linda Shapiro

In the clinical treatment of mood disorders, the complex behavioral symptoms presented by patients and variability of patient response to particular medication classes can create difficulties in providing fast and reliable treatment when…

Machine Learning · Computer Science 2024-02-13 Bradley T. Baker , Mustafa S. Salman , Zening Fu , Armin Iraji , Elizabeth Osuch , Jeremy Bockholt , Vince D. Calhoun

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study…

Computation and Language · Computer Science 2024-05-14 Yu He Ke , Rui Yang , Sui An Lie , Taylor Xin Yi Lim , Hairil Rizal Abdullah , Daniel Shu Wei Ting , Nan Liu

The rapid advancement of large language models has fundamentally shifted the bottleneck in AI development from computational power to data availability-with countless valuable datasets remaining hidden across specialized repositories,…

Artificial Intelligence · Computer Science 2025-08-12 Keyu Li , Mohan Jiang , Dayuan Fu , Yunze Wu , Xiangkun Hu , Dequan Wang , Pengfei Liu

This paper describes the development of Psychlysis, a work-in-progress questionnaire-based machine learning application analyzing the user's current state of mind and suggesting ways to improve their mood using Machine Learning. The…

Human-Computer Interaction · Computer Science 2025-12-11 Hemakshi Jani , Mitish Karia , Meet Gohil , Rahul Bhadja , Aznam Yacoub , Shafaq Khan

AI systems in healthcare research have shown potential to increase patient throughput and assist clinicians, yet progress is constrained by limited access to real patient data. To address this issue, we present a zero-shot, knowledge-guided…

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

During psychiatric assessment, clinicians observe not only what patients report, but important nonverbal signs such as tone, speech rate, fluency, responsiveness, and body language. Weighing and integrating these different information…

Machine Learning · Computer Science 2025-12-19 Agnes Norbury , George Fairs , Alexandra L. Georgescu , Matthew M. Nour , Emilia Molimpakis , Stefano Goria

The COVID-19 pandemic has forced many people to limit their social activities, which has resulted in a rise in mental illnesses, particularly depression. To diagnose these illnesses with accuracy and speed, and prevent severe outcomes such…

Machine Learning · Computer Science 2023-11-14 Hossein Simchi , Samira Tajik

Mental disorders represent a critical global health challenge, and social media is increasingly viewed as a vital resource for real-time digital phenotyping and intervention. To leverage this data, large language models (LLMs) have been…

Computation and Language · Computer Science 2025-12-23 Zhuohan Ge , Darian Li , Yubo Wang , Nicole Hu , Xinyi Zhu , Haoyang Li , Xin Zhang , Mingtao Zhang , Shihao Qi , Yuming Xu , Han Shi , Chen Jason Zhang , Qing Li

Clinical trials are pivotal for developing new medical treatments but typically carry risks such as patient mortality and enrollment failure that waste immense efforts spanning over a decade. Applying artificial intelligence (AI) to predict…

Mental disorders such as Autism Spectrum Disorders (ASD) are heterogeneous disorders that are notoriously difficult to diagnose, especially in children. The current psychiatric diagnostic process is based purely on the behavioural…

Machine Learning · Computer Science 2019-04-17 Taban Eslami , Vahid Mirjalili , Alvis Fong , Angela Laird , Fahad Saeed

The development of intelligent agents, particularly those powered by language models (LMs), has shown a critical role in various environments that require intelligent and autonomous decision-making. Environments are not passive testing…

Artificial Intelligence · Computer Science 2025-10-21 Antonin Sulc , Thorsten Hellert

We envision the Full-Body AI Agent as a comprehensive AI system designed to simulate, analyze, and optimize the dynamic processes of the human body across multiple biological levels. By integrating computational models, machine learning…

Tissues and Organs · Quantitative Biology 2025-08-28 Aoqi Wang , Jiajia Liu , Jianguo Wen , Yangyang Luo , Zhiwei Fan , Liren Yang , Xi Hu , Ruihan Luo , Yankai Yu , Sophia Li , Weiling Zhao , Xiaobo Zhou

Large language models (LLMs) are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned, particularly in sensitive or high-risk contexts. Existing…

Human-Computer Interaction · Computer Science 2026-01-21 Jiwon Kim , Violeta J. Rodriguez , Dong Whi Yoo , Eshwar Chandrasekharan , Koustuv Saha

Retrieval-augmented generation (RAG) systems improve large language model outputs by incorporating external knowledge, enabling more informed and context-aware responses. However, the effectiveness and trustworthiness of these systems…

Computation and Language · Computer Science 2025-08-27 Ilias Driouich , Hongliu Cao , Eoin Thomas