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Direct Preference Optimization (DPO) has emerged as a prominent algorithm for the direct and robust alignment of Large Language Models (LLMs) with human preferences, offering a more straightforward alternative to the complex Reinforcement…

DPO (Direct Preference Optimization) has become a widely used offline preference optimization algorithm due to its simplicity and training stability. However, DPO is prone to overfitting and collapse. To address these challenges, we propose…

Preference optimization for diffusion models aims to align them with human preferences for images. Previous methods typically use Vision-Language Models (VLMs) as pixel-level reward models to approximate human preferences. However, when…

Radiography Report Generation (RRG) has gained significant attention in medical image analysis as a promising tool for alleviating the growing workload of radiologists. However, despite numerous advancements, existing methods have yet to…

Direct Preference Optimization (DPO) have emerged as a popular method for aligning Large Language Models (LLMs) with human preferences. While DPO effectively preserves the relative ordering between chosen and rejected responses through…

Human image generation is a key focus in image synthesis due to its broad applications, but even slight inaccuracies in anatomy, pose, or details can compromise realism. To address these challenges, we explore Direct Preference Optimization…

Although LLMs have achieved significant success, their reliance on large volumes of human-annotated data has limited their potential for further scaling. In this situation, utilizing self-generated synthetic data has become crucial for…

Existing methods for preference tuning of text-to-image (T2I) diffusion models often rely on computationally expensive generation steps to create positive and negative pairs of images. These approaches frequently yield training pairs that…

Aligning text-to-image (T2I) diffusion models with human preferences has emerged as a critical research challenge. While recent advances in this area have extended preference optimization techniques from large language models (LLMs) to the…

RLHF techniques like DPO can significantly improve the generation quality of text-to-image diffusion models. However, these methods optimize for a single reward that aligns model generation with population-level preferences, neglecting the…

Our goal is to enable large language models (LLMs) to balance multiple human preference dimensions; such as helpfulness, safety, and verbosity, through principled and controllable alignment. Existing preference optimization methods,…

Post-training alignment of diffusion models relies on simplified signals, such as scalar rewards or binary preferences. This limits alignment with complex human expertise, which is hierarchical and fine-grained. To address this, we first…

Direct Preference Optimization (DPO) simplifies reinforcement learning from human feedback (RLHF) for large language models (LLMs) by directly optimizing human preferences without an explicit reward model. We find that during DPO training,…

In this paper, we introduce \emph{refined Direct Preference Optimization} (rDPO), a method for improving the behavioral alignment of Large Language Models (LLMs) without the need for human-annotated data. The method involves creating…

Large Vision-Language Models (LVLMs) hold immense potential for complex multimodal instruction following, yet their development is often hindered by the high cost and inconsistency of human annotation required for effective fine-tuning and…

Direct Preference Optimization (DPO) and its variants have become the de facto standards for aligning large language models (LLMs) with human preferences or specific goals. However, DPO requires high-quality preference data and suffers from…

While dense pixel-wise annotations remain the gold standard for medical image segmentation, they are costly to obtain and limit scalability. In contrast, many deployed systems already produce inexpensive automatic quality-control (QC)…

Direct Preference Optimization (DPO) has gained significant attention for its simplicity and computational efficiency in aligning large language models (LLMs). Recent advancements have extended DPO to multimodal scenarios, achieving strong…

Diffusion models have achieved promising results for Structure-Based Drug Design (SBDD). Nevertheless, high-quality protein subpocket and ligand data are relatively scarce, which hinders the models' generation capabilities. Recently, Direct…

Direct Preference Optimization (DPO) is broadly utilized for aligning Large Language Models (LLMs) with human values because of its flexibility. Despite its effectiveness, it has been observed that the capability of DPO to generate…