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This study integrates PET metabolic information with CT anatomical structures to establish a 3D multimodal segmentation dataset for lymphoma based on whole-body FDG PET/CT examinations, which bridges the gap of the lack of standardised…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Jiajun Ding , Beiyao Zhu , Xiaosheng Liu , Lishen Zhang , Zhao Liu

An accurate steatosis quantification with pathology tissue samples is of high clinical importance. However, such pathology measurement is manually made in most clinical practices, subject to severe reader variability due to large sampling…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Mousumi Roy , Fusheng Wang , George Teodoro , Miriam B Vos , Alton Brad Farris , Jun Kong

Background & Aims: Hepatic steatosis is a major cause of chronic liver disease. 2D ultrasound is the most widely used non-invasive tool for screening and monitoring, but associated diagnoses are highly subjective. We developed a scalable…

Image and Video Processing · Electrical Eng. & Systems 2021-10-13 Bowen Li , Dar-In Tai , Ke Yan , Yi-Cheng Chen , Shiu-Feng Huang , Tse-Hwa Hsu , Wan-Ting Yu , Jing Xiao , Le Lu , Adam P. Harrison

Liver cancer, especially hepatocellular carcinoma (HCC), imposes a substantial global disease burden. Accurate diagnosis and prognostic assessment directly influence treatment selection and patient survival, and pathological examination…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ying Xiao , Shimiao Tang , Xitong Ling , Weiming Chen , Jun Wang , Jiawen Li , Huaitian Yuan , Jianghui Yang , Bowen Li , Huan Li , Yiting Meng , Tian Guan , Yonghong He , Hongfang Yin

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

Purpose: In laparoscopic liver surgery (LLS), pre-operative information can be overlaid onto the intra-operative scene by registering a 3D pre-operative model to the intra-operative partial surface reconstructed from the laparoscopic video.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Zixin Yang , Richard Simon , Cristian A. Linte

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Objectives: to propose a fully-automatic computer-aided diagnosis (CAD) solution for liver lesion characterization, with uncertainty estimation. Methods: we enrolled 400 patients who had either liver resection or a biopsy and was diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Peng Wang , Yuhsuan Wu , Bolin Lai , Xiao-Yun Zhou , Le Lu , Wendi Liu , Huabang Zhou , Lingyun Huang , Jing Xiao , Adam P. Harrison , Ningyang Jia , Heping Hu

Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

Histopathology, the microscopic study of diseased tissue, is increasingly digitized, enabling improved visualization and streamlined workflows. An important task in histopathology is the segmentation of cells and glands, essential for…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Philipp Endres , Valentin Koch , Julia A. Schnabel , Carsten Marr

Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software environments, and few open-source options exist for deploying models in…

Recently, histopathology vision-language foundation models (VLMs) have gained popularity due to their enhanced performance and generalizability across different downstream tasks. However, most existing histopathology benchmarks are either…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Roba Al Majzoub , Hashmat Malik , Muzammal Naseer , Zaigham Zaheer , Tariq Mahmood , Salman Khan , Fahad Khan

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

Purpose: Evaluating deformable image registration (DIR) algorithms is vital for enhancing algorithm performance and gaining clinical acceptance. However, there's a notable lack of dependable DIR benchmark datasets for assessing DIR…

Medical Physics · Physics 2024-04-09 Zhendong Zhang , Edward Robert Criscuolo , Yao Hao , Deshan Yang

Computer-aided diagnosis (CAD) technology can assist clinicians in evaluating liver lesions and intervening with treatment in time. Although CAD technology has advanced in recent years, the application scope of existing datasets remains…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Zhe Liu , Kai Han , Siqi Ma , Yan Zhu , Jun Chen , Chongwen Lyu , Xinyi Qiu , Chengxuan Qian , Yuqing Song , Yi Liu , Liyuan Tian , Yang Ji , Yuefeng Li

Glomerular pathology is central to the diagnosis and prognosis of renal diseases, yet the heterogeneity of glomerular morphology and fine-grained lesion patterns remain challenging for current AI approaches. We present GloPath, an…

Pathology reports are structured, multi-granular documents encoding diagnostic conclusions, histological grades, and ancillary test results across one or more anatomical sites; yet existing pathology vision-language models (VLMs) reduce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Ruicheng Yuan , Zhenxuan Zhang , Anbang Wang , Liwei Hu , Xiangqian Hua , Yaya Peng , Jiawei Luo , Guang Yang

Recent studies have made significant progress in developing large language models (LLMs) in the medical domain, which can answer expert-level questions and demonstrate the potential to assist clinicians in real-world clinical scenarios.…

Computation and Language · Computer Science 2025-04-18 Sangwook Kim , Soonyoung Lee , Jongseong Jang

Liver transplantation is a life-saving procedure for patients with end-stage liver disease. There are two main challenges in liver transplant: finding the best matching patient for a donor and ensuring transplant equity among different…

Machine Learning · Computer Science 2024-03-04 Can Li , Xiaoqian Jiang , Kai Zhang

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

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