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Direct Preference Optimization (DPO) is broadly utilized for aligning Large Language Models (LLMs) with human values because of its flexibility. Despite its effectiveness, it has been observed that the capability of DPO to generate…

Reinforcement learning from human feedback (RLHF) has been extensively employed to align large language models with user intent. However, proximal policy optimization (PPO) based RLHF is occasionally unstable requiring significant…

Aligning the output of Large Language Models (LLMs) with human preferences (e.g., by means of reinforcement learning with human feedback, or RLHF) is essential for ensuring their effectiveness in real-world scenarios. Despite significant…

Adapting Large Language Models (LLMs) for agent tasks is critical in developing language agents. Direct Preference Optimization (DPO) is a promising technique for this adaptation with the alleviation of compounding errors, offering a means…

De novo molecular design has extensive applications in drug discovery and materials science. The vast chemical space renders direct molecular searches computationally prohibitive, while traditional experimental screening is both time- and…

Our goal is to enable large language models (LLMs) to balance multiple human preference dimensions; such as helpfulness, safety, and verbosity, through principled and controllable alignment. Existing preference optimization methods,…

The last year has witnessed the rapid progress of large language models (LLMs) across diverse domains. Among them, CodeLLMs have garnered particular attention because they can not only assist in completing various programming tasks but also…

Direct Preference Optimization (DPO) has emerged as an effective approach for aligning large language models (LLMs) with human preferences. However, its performance is highly dependent on the quality of the underlying human preference data.…

The alignment of large language models with human values presents a critical challenge, particularly when balancing conflicting objectives like helpfulness and harmlessness. Existing approaches, such as Reinforcement Learning from Human…

Preference-based alignment objectives have been widely adopted, from RLHF-style pairwise learning in large language models to emerging applications in recommender systems. Yet, existing work rarely examines how Direct Preference…

Protein inverse folding-that is, predicting an amino acid sequence that will fold into the desired 3D structure-is an important problem for structure-based protein design. Machine learning based methods for inverse folding typically use…

Large Language Models (LLMs) have demonstrated remarkable potential in automating software development tasks. While recent advances leverage Supervised Fine-Tuning (SFT) and Direct Preference Optimization (DPO) to align models with human…

Preference optimization is a critical post-training technique used to align large language models (LLMs) with human preferences, typically by fine-tuning on ranked response pairs. While methods like Direct Preference Optimization (DPO) have…

Reinforcement Learning from Human Feedback has emerged as a standard for aligning diffusion models. However, we identify a fundamental limitation in the standard DPO formulation because it relies on the Bradley-Terry model to aggregate…

Aligning large language models (LLMs) with human values is an increasingly critical step in post-training. Direct Preference Optimization (DPO) has emerged as a simple, yet effective alternative to reinforcement learning from human feedback…

Radiography Report Generation (RRG) has gained significant attention in medical image analysis as a promising tool for alleviating the growing workload of radiologists. However, despite numerous advancements, existing methods have yet to…

Enhancing the conformity of large language models (LLMs) to human preferences remains an ongoing research challenge. Recently, offline approaches such as Direct Preference Optimization (DPO) have gained prominence as attractive options due…

Language model (LM) post-training (or alignment) involves maximizing a reward function that is derived from preference annotations. Direct Preference Optimization (DPO) is a popular offline alignment method that trains a policy directly on…

Direct Preference Optimization (DPO) is an efficient alignment technique that steers LLMs towards preferable outputs by training on preference data, bypassing the need for explicit reward models. Its simplicity enables easy adaptation to…

DPO has become a widely adopted alternative to RLHF for aligning LLMs with human preferences, eliminating the need for a separate reward model or RL loop. Recent theoretical analysis uncovers an asymmetric gradient behavior in DPO: the loss…