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OpenAI o1 has shown that applying reinforcement learning to integrate reasoning steps directly during inference can significantly improve a model's reasoning capabilities. This result is exciting as the field transitions from the…

Artificial Intelligence · Computer Science 2025-02-18 Jun Wang

The increasing scale of large language models (LLMs) brings emergent abilities to various complex tasks requiring reasoning, such as arithmetic and commonsense reasoning. It is known that the effective design of task-specific prompts is…

Computation and Language · Computer Science 2024-07-23 Shizhe Diao , Pengcheng Wang , Yong Lin , Rui Pan , Xiang Liu , Tong Zhang

Recent large reasoning models (LRMs) have demonstrated strong reasoning capabilities through reinforcement learning (RL). These improvements have primarily been observed within the short-context reasoning tasks. In contrast, extending LRMs…

Computation and Language · Computer Science 2025-05-28 Fanqi Wan , Weizhou Shen , Shengyi Liao , Yingcheng Shi , Chenliang Li , Ziyi Yang , Ji Zhang , Fei Huang , Jingren Zhou , Ming Yan

We examine the reasoning and planning capabilities of large language models (LLMs) in solving complex tasks. Recent advances in inference-time techniques demonstrate the potential to enhance LLM reasoning without additional training by…

Artificial Intelligence · Computer Science 2025-02-19 Shubham Parashar , Blake Olson , Sambhav Khurana , Eric Li , Hongyi Ling , James Caverlee , Shuiwang Ji

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu

Question: What is the performance and reasoning ability of OpenAI o1 compared to other large language models in addressing ophthalmology-specific questions? Findings: This study evaluated OpenAI o1 and five LLMs using 6,990 ophthalmological…

Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11…

Reasoning-enabled large language models (LLMs) excel in logical tasks, yet their utility for evaluating natural language generation remains unexplored. This study systematically compares reasoning LLMs with non-reasoning counterparts across…

Computation and Language · Computer Science 2025-06-02 Daniil Larionov , Sotaro Takeshita , Ran Zhang , Yanran Chen , Christoph Leiter , Zhipin Wang , Christian Greisinger , Steffen Eger

This survey explores recent advancements in reasoning large language models (LLMs) designed to mimic "slow thinking" - a reasoning process inspired by human cognition, as described in Kahneman's Thinking, Fast and Slow. These models, like…

Artificial Intelligence · Computer Science 2025-05-09 Qianjun Pan , Wenkai Ji , Yuyang Ding , Junsong Li , Shilian Chen , Junyi Wang , Jie Zhou , Qin Chen , Min Zhang , Yulan Wu , Liang He

Recent advancements in single-cell multi-omics, particularly RNA-seq, have provided profound insights into cellular heterogeneity and gene regulation. While pre-trained language model (PLM) paradigm based single-cell foundation models have…

Genomics · Quantitative Biology 2026-01-12 Haoran Wang , Xuanyi Zhang , Shuangsang Fang , Longke Ran , Ziqing Deng , Yong Zhang , Yuxiang Li , Shaoshuai Li

Optimization modeling and solving are fundamental to the application of Operations Research (OR) in real-world decision making, yet the process of translating natural language problem descriptions into formal models and solver code remains…

Artificial Intelligence · Computer Science 2025-11-13 Zezhen Ding , Zhen Tan , Jiheng Zhang , Tianlong Chen

Despite growing interest in using large language models (LLMs) to automate annotation, their effectiveness in complex, nuanced, and multi-dimensional labelling tasks remains relatively underexplored. This study focuses on annotation for the…

Information Retrieval · Computer Science 2025-07-02 Leila Tavakoli , Hamed Zamani

Large Language Models (LLMs), such as OpenAI's o1 and DeepSeek's R1, excel at advanced reasoning tasks like math and coding via Reinforcement Learning with Verifiable Rewards (RLVR), but still struggle with puzzles solvable by humans…

Computation and Language · Computer Science 2025-06-10 Jiangjie Chen , Qianyu He , Siyu Yuan , Aili Chen , Zhicheng Cai , Weinan Dai , Hongli Yu , Qiying Yu , Xuefeng Li , Jiaze Chen , Hao Zhou , Mingxuan Wang

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

While Large Language Models (LLMs) have demonstrated proficiency in handling complex queries, much of the past work has depended on extensively annotated datasets by human experts. However, this reliance on fully-supervised annotations…

Computation and Language · Computer Science 2024-05-08 Yongqi Tong , Sizhe Wang , Dawei Li , Yifan Wang , Simeng Han , Zi Lin , Chengsong Huang , Jiaxin Huang , Jingbo Shang

Efficiently acquiring external knowledge and up-to-date information is essential for effective reasoning and text generation in large language models (LLMs). Prompting advanced LLMs with reasoning capabilities to use search engines during…

Computation and Language · Computer Science 2025-08-07 Bowen Jin , Hansi Zeng , Zhenrui Yue , Jinsung Yoon , Sercan Arik , Dong Wang , Hamed Zamani , Jiawei Han

Tabular data serves as the backbone of modern data analysis and scientific research. While Large Language Models (LLMs) fine-tuned via Supervised Fine-Tuning (SFT) have significantly improved natural language interaction with such…

Although Large Language Models (LLMs) have demonstrated remarkable progress, their proficiency in graph-related tasks remains notably limited, hindering the development of truly general-purpose models. Previous attempts, including…

Machine Learning · Computer Science 2025-08-20 Xiaojun Guo , Ang Li , Yifei Wang , Stefanie Jegelka , Yisen Wang

Choosing a Large Language Model (LLM) for a given task requires comparing many strong candidates, yet standard evaluation relies on costly annotations over fixed evaluation sets. To address this challenge, we develop SELECT-LLM, the first…

Computation and Language · Computer Science 2026-05-26 Yavuz Durmazkeser , Patrik Okanovic , Andreas Kirsch , Torsten Hoefler , Nezihe Merve Gürel

The breakthrough of OpenAI o1 highlights the potential of enhancing reasoning to improve LLM. Yet, most research in reasoning has focused on mathematical tasks, leaving domains like medicine underexplored. The medical domain, though…

Computation and Language · Computer Science 2024-12-30 Junying Chen , Zhenyang Cai , Ke Ji , Xidong Wang , Wanlong Liu , Rongsheng Wang , Jianye Hou , Benyou Wang