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Multiple instance learning (MIL) has been increasingly used in the classification of histopathology whole slide images (WSIs). However, MIL approaches for this specific classification problem still face unique challenges, particularly those…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Hongrun Zhang , Yanda Meng , Yitian Zhao , Yihong Qiao , Xiaoyun Yang , Sarah E. Coupland , Yalin Zheng

Multiple Instance Learning (MIL) has enabled weakly supervised analysis of whole-slide images (WSIs) in computational pathology. However, traditional MIL approaches often lose crucial contextual information, while transformer-based…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Xitong Ling , Minxi Ouyang , Xiaoxiao Li , Jiawen Li , Ying Chen , Yuxuan Sun , Xinrui Chen , Tian Guan , Xiaoping Liu , Yonghong He

Telemedicine refers to the use of information and communication technology to assist with medical information and services. In health care applications, high reliable communication links between the health care provider and the desired…

Information Theory · Computer Science 2019-06-18 Ali Momeni , Hamid Khoshfekr Rudsari , Mohammad Reza Javan , Nader Mokari , Eduard A. Jorswieck , Mahdi Orooji

Weakly supervised whole slide image classification is a key task in computational pathology, which involves predicting a slide-level label from a set of image patches constituting the slide. Constructing models to solve this task involves…

The label scarcity problem is the main challenge that hinders the wide application of deep learning systems in automatic cardiovascular diseases (CVDs) detection using electrocardiography (ECG). Tuning pre-trained models alleviates this…

Machine Learning · Computer Science 2024-11-18 Rushuang Zhou , Lei Clifton , Zijun Liu , Kannie W. Y. Chan , David A. Clifton , Yuan-Ting Zhang , Yining Dong

In this paper, we introduce a Variational Autoencoder (VAE) based training approach that can compress and decompress cancer pathology slides at a compression ratio of 1:512, which is better than the previously reported state of the art…

Weakly supervised whole slide image classification is usually formulated as a multiple instance learning (MIL) problem, where each slide is treated as a bag, and the patches cut out of it are treated as instances. Existing methods either…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Linhao Qu , Yingfan Ma , Xiaoyuan Luo , Manning Wang , Zhijian Song

We introduce ReaMIL (Reasoning- and Evidence-Aware MIL), a multiple instance learning approach for whole-slide histopathology that adds a light selection head to a strong MIL backbone. The head produces soft per-tile gates and is trained…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Hyun Do Jung , Jungwon Choi , Hwiyoung Kim

Contrastive learning (CL) for Vision Transformers (ViTs) in image domains has achieved performance comparable to CL for traditional convolutional backbones. However, in 3D point cloud pretraining with ViTs, masked autoencoder (MAE) modeling…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Bin Ren , Guofeng Mei , Danda Pani Paudel , Weijie Wang , Yawei Li , Mengyuan Liu , Rita Cucchiara , Luc Van Gool , Nicu Sebe

In histopathology, intelligent diagnosis of Whole Slide Images (WSIs) is essential for automating and objectifying diagnoses, reducing the workload of pathologists. However, diagnostic models often face the challenge of forgetting…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Weixi Zheng , Aoling Huang , Jingping Yuan , Haoyu Zhao , Zhou Zhao , Yongchao Xu , Thierry Géraud

The Vision Transformer (ViT) has demonstrated remarkable performance in Self-Supervised Learning (SSL) for 3D medical image analysis. Masked AutoEncoder (MAE) for feature pre-training can further unleash the potential of ViT on various…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Jiaxin Zhuang , Linshan Wu , Qiong Wang , Peng Fei , Varut Vardhanabhuti , Lin Luo , Hao Chen

Detecting rare and diverse anomalies in highly imbalanced datasets-such as Advanced Persistent Threats (APTs) in cybersecurity-remains a fundamental challenge for machine learning systems. Active learning offers a promising direction by…

Machine Learning · Computer Science 2026-02-04 Sidahmed Benabderrahmane , Petko Valtchev , James Cheney , Talal Rahwan

Self-Supervised Learning (SSL) presents an exciting opportunity to unlock the potential of vast, untapped clinical datasets, for various downstream applications that suffer from the scarcity of labeled data. While SSL has revolutionized…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Tassilo Wald , Constantin Ulrich , Stanislav Lukyanenko , Andrei Goncharov , Alberto Paderno , Maximilian Miller , Leander Maerkisch , Paul F. Jäger , Klaus Maier-Hein

Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Compared to the multi-stage self-supervised multi-view stereo (MVS) method, the end-to-end (E2E) approach has received more attention due to its concise and efficient training pipeline. Recent E2E self-supervised MVS approaches have…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Qiang Zhou , Chaohui Yu , Jingliang Li , Yuang Liu , Jing Wang , Zhibin Wang

Classification on long-tailed distributed data is a challenging problem, which suffers from serious class-imbalance and hence poor performance on tail classes with only a few samples. Owing to this paucity of samples, learning on the tail…

Computation and Language · Computer Science 2022-07-25 Taha ValizadehAslani , Yiwen Shi , Jing Wang , Ping Ren , Yi Zhang , Meng Hu , Liang Zhao , Hualou Liang

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

Image and Video Processing · Electrical Eng. & Systems 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Multi-instance learning (MIL) is a form of weakly supervised learning where a single class label is assigned to a bag of instances while the instance-level labels are not available. Training classifiers to accurately determine the bag label…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Bin Li , Kevin W. Eliceiri

Recently, end-to-end (E2E) automatic speech recognition (ASR) systems have garnered tremendous attention because of their great success and unified modeling paradigms in comparison to conventional hybrid DNN-HMM ASR systems. Despite the…

Audio and Speech Processing · Electrical Eng. & Systems 2020-05-19 Tien-Hong Lo , Shi-Yan Weng , Hsiu-Jui Chang , Berlin Chen