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Multimodal signals, including text, audio, image, and video, can be integrated into Semantic Communication (SC) systems to provide an immersive experience with low latency and high quality at the semantic level. However, the multimodal SC…

Artificial Intelligence · Computer Science 2024-08-06 Feibo Jiang , Li Dong , Yubo Peng , Kezhi Wang , Kun Yang , Cunhua Pan , Xiaohu You

Recent research on spatial and spatio-temporal model checking provides novel image analysis methodologies, rooted in logical methods for topological spaces. Medical Imaging (MI) is a field where such methods show potential for…

Logic in Computer Science · Computer Science 2018-11-16 Fabrizio Banci Buonamici , Gina Belmonte , Vincenzo Ciancia , Diego Latella , Mieke Massink

Large language models (LLMs) and vision-language models (VLMs) have demonstrated remarkable performance across a wide range of tasks and domains. Despite this promise, spatial understanding and reasoning -- a fundamental component of human…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Jiayu Wang , Yifei Ming , Zhenmei Shi , Vibhav Vineet , Xin Wang , Yixuan Li , Neel Joshi

Multimodal Large Language Models (MLLMs) have achieved remarkable progress in various multimodal tasks. To pursue higher intelligence in space, MLLMs require integrating multiple spatial capabilities, even for handling simple and normal…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Ziyang Gong , Wenhao Li , Oliver Ma , Songyuan Li , Zhaokai Wang , Songyuan Li , Jiayi Ji , Xue Yang , Gen Luo , Junchi Yan , Rongrong Ji

New era has unlocked exciting possibilities for extending Large Language Models (LLMs) to tackle 3D vision-language tasks. However, most existing 3D multimodal LLMs (MLLMs) rely on compressing holistic 3D scene information or segmenting…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Xiaoyan Wang , Zeju Li , Yifan Xu , Jiaxing Qi , Zhifei Yang , Ruifei Ma , Xiangde Liu , Chao Zhang

We explore the application of large language models (LLMs) to empower domain experts in integrating large, heterogeneous, and noisy urban spatial datasets. Traditional rule-based integration methods are unable to cover all edge cases,…

Artificial Intelligence · Computer Science 2025-08-08 Bin Han , Robert Wolfe , Anat Caspi , Bill Howe

Recent studies have demonstrated the feasibility of modeling single-cell data as natural languages and the potential of leveraging powerful large language models (LLMs) for understanding cell biology. However, a comprehensive evaluation of…

Quantitative Methods · Quantitative Biology 2025-05-14 Fan Zhang , Tianyu Liu , Zhihong Zhu , Hao Wu , Haixin Wang , Donghao Zhou , Yefeng Zheng , Kun Wang , Xian Wu , Pheng-Ann Heng

Despite the ubiquity of large language models (LLMs) in AI research, the question of embodiment in LLMs remains underexplored, distinguishing them from embodied systems in robotics where sensory perception directly informs physical action.…

Computation and Language · Computer Science 2024-05-28 Philipp Wicke , Lennart Wachowiak

Development and homeostasis in multicellular systems both require exquisite control over spatial molecular pattern formation and maintenance. Advances in spatially-resolved and high-throughput molecular imaging methods such as multiplexed…

Quantitative Methods · Quantitative Biology 2023-03-30 Alex J. Lee , Robert Cahill , Reza Abbasi-Asl

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Genuine spatial reasoning relies on the capacity to construct and manipulate coherent internal spatial representations, often conceptualized as mental models, rather than merely processing surface linguistic associations. While large…

Artificial Intelligence · Computer Science 2026-03-04 Peiyao Jiang , Zequn Qin , Xi Li

Spatial cognition is fundamental to real-world multimodal intelligence, allowing models to effectively interact with the physical environment. While multimodal large language models (MLLMs) have made significant strides, existing benchmarks…

Artificial Intelligence · Computer Science 2026-05-08 Peiran Xu , Sudong Wang , Yao Zhu , Jianing Li , Gege Qi , Yunjian Zhang

Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data remains prohibitively expensive, and traditional fixed-grid…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Chongyu Qu , Juming Xiong , Siqi Lu , Zhengyi Lu , Yanfan Zhu , Marilyn Lionts , Yuechen Yang , Yalin Zheng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

This paper proposes spatial lattice modulation (SLM), a spatial modulation method for multipleinput-multiple-output (MIMO) systems. The key idea of SLM is to jointly exploit spatial, in-phase, and quadrature dimensions to modulate…

Information Theory · Computer Science 2018-05-23 Jiwook Choi , Yunseo Nam , Namyoon Lee

Spatial reasoning, which requires ability to perceive and manipulate spatial relationships in the 3D world, is a fundamental aspect of human intelligence, yet remains a persistent challenge for Multimodal large language models (MLLMs).…

Artificial Intelligence · Computer Science 2025-11-21 Weichen Liu , Qiyao Xue , Haoming Wang , Xiangyu Yin , Boyuan Yang , Wei Gao

Multiplexed immunofluorescence microscopy captures detailed measurements of spatially resolved, multiple biomarkers simultaneously, revealing tissue composition and cellular interactions in situ among single cells. The growing scale and…

Software Engineering · Computer Science 2025-06-03 Fang Liu , Rui He , Andrei Bombin , Ahmad B. Abdallah , Omar Eldaghar , Tommy R. Sheeley , Sam E. Ying , George Zaki

Large language models (LLMs) exhibit remarkable in-context learning (ICL) capabilities. However, the underlying working mechanism of ICL remains poorly understood. Recent research presents two conflicting views on ICL: One emphasizes the…

Computation and Language · Computer Science 2024-10-10 Anhao Zhao , Fanghua Ye , Jinlan Fu , Xiaoyu Shen

In this paper, we introduce Semantic Layering in Room Segmentation via LLMs (SeLRoS), an advanced method for semantic room segmentation by integrating Large Language Models (LLMs) with traditional 2D map-based segmentation. Unlike previous…

Robotics · Computer Science 2024-03-20 Taehyeon Kim , Byung-Cheol Min

Existing evaluations of multimodal large language models (MLLMs) on spatial intelligence are typically fragmented and limited in scope. In this work, we aim to conduct a holistic assessment of the spatial understanding capabilities of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Haoning Wu , Xiao Huang , Yaohui Chen , Ya Zhang , Yanfeng Wang , Weidi Xie

SpatialLM is a large language model designed to process 3D point cloud data and generate structured 3D scene understanding outputs. These outputs include architectural elements like walls, doors, windows, and oriented object boxes with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Yongsen Mao , Junhao Zhong , Chuan Fang , Jia Zheng , Rui Tang , Hao Zhu , Ping Tan , Zihan Zhou