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A family of collective variables is proposed to perform exact dynamical coarse-graining even in systems without time scale separation. More precisely, it is shown that these variables are not slow in general but they satisfy an overdamped…

Statistical Mechanics · Physics 2015-06-19 Jianfeng Lu , Eric Vanden-Eijnden

A continuum grain boundary model is developed that uses experimentally measured grain boundary energy data as a function of misorientation to simulate idealized grain boundary evolution in a 1-D grain array. The model uses a continuum…

Materials Science · Physics 2024-01-29 Syed Ansari , Amit Acharya , Alankar Alankar

Tissue dynamics and collective cell motion are crucial biological processes. Their biological machinery is mostly known, and simulation models such as the "active vertex model" (AVM) exist and yield reasonable agreement with experimental…

Soft Condensed Matter · Physics 2023-11-16 Gloria Triguero-Platero , Falko Ziebert , Luis L. Bonilla

Coarse-grained (CG) force field methods for molecular systems are a crucial tool to simulate large biological macromolecules and are therefore essential for characterisations of biomolecular systems. While state-of-the-art deep learning…

Far from equilibrium, neural systems self-organize across multiple scales. Exploiting multiscale self-organization in neuroscience and artificial intelligence requires a computational framework for modeling the effective non-equilibrium…

Neurons and Cognition · Quantitative Biology 2025-10-09 Nathan X. Kodama

While existing mathematical descriptions can accurately account for phenomena at microscopic scales (e.g. molecular dynamics), these are often high-dimensional, stochastic and their applicability over macroscopic time scales of physical…

Machine Learning · Statistics 2016-09-08 P. S. Koutsourelakis , Elias Bilionis

We derive a mesoscopic modeling and simulation technique that is very close to the technique known as dissipative particle dynamics. The model is derived from molecular dynamics by means of a systematic coarse-graining procedure. Thus the…

Soft Condensed Matter · Physics 2009-10-31 Eirik G. Flekkoy , Peter V. Coveney , Gianni De Fabritiis

After coarse-graining a complex system, the dynamics of its macro-state may exhibit more pronounced causal effects than those of its micro-state. This phenomenon, known as causal emergence, is quantified by the indicator of effective…

Information Theory · Computer Science 2025-02-13 Kaiwei Liu , Bing Yuan , Jiang Zhang

We review a few representative examples of granular experiments or models where phase separation, accompanied by domain coarsening, is a relevant phenomenon. We first elucidate the intrinsic non-equilibrium, or athermal, nature of granular…

Statistical Mechanics · Physics 2015-04-29 Andrea Baldassarri , Andrea Puglisi , Alessandro Sarracino

We develop a machine-learning method for coarse-graining condensed-phase molecular systems using anisotropic particles. The method extends currently available high-dimensional neural network potentials by addressing molecular anisotropy. We…

Statistical Mechanics · Physics 2023-07-12 Marltan O. Wilson , David M. Huang

Stochastic dynamics, such as molecular dynamics, are important in many scientific applications. However, summarizing and analyzing the results of such simulations is often challenging, due to the high dimension in which simulations are…

Dynamical Systems · Mathematics 2023-09-11 David Aristoff , Mats Johnson , Danny Perez

In the context of the recently developed "equation-free" approach to the computer-assisted analysis of complex systems, we illustrate the computation of coarsely self-similar solutions. Dynamic renormalization and fixed point algorithms for…

Computational Physics · Physics 2007-05-23 L. Chen , P. G. Debenedetti , C. W. Gear , I. G. Kevrekidis

In this paper, we examine how to build coarse-grain transport models consistently from the kinetic to fluid regimes. The internal energy of the gas particles is described through a state-to-state approach. A kinetic equation allows us to…

Fluid Dynamics · Physics 2021-03-15 Erik Torres , Georgios Bellas-Chatzigeorgis , Thierry E. Magin

Integrating out fast degrees of freedom is known to yield, to a good approximation, memory-less, i.e. Markovian, dynamics. In the presence of such a time-scale separation local detailed balance is believed to emerge and to guarantee…

Statistical Mechanics · Physics 2023-12-12 David Hartich , Aljaž Godec

Hybrid multiscale modelling has emerged as a useful framework for modelling complex biological phenomena. However, when accounting for stochasticity in the internal dynamics of agents, these models frequently become computationally…

Quantitative Methods · Quantitative Biology 2021-05-11 Daria Stepanova , Helen M. Byrne , Philip K. Maini , Tomás Alarcón

Stochastic thermodynamics provides the framework to analyze thermodynamic laws and quantities along individual trajectories of small but fully observable systems. If the observable level fails to capture all relevant degrees of freedom,…

Statistical Mechanics · Physics 2024-07-01 Julius Degünther , Jann van der Meer , Udo Seifert

To acquire the ability to numerically study the rheology of particulate two-phase flows that lack scale separation, we present a general method to average or coarse-grain the equations of motion of a mixture of a continuous fluid of…

Fluid Dynamics · Physics 2026-01-22 Thomas Pähtz , Yulan Chen , Rui Zhu , Katharina Tholen , Zhiguo He

Microscopic machines utilize free energy to create and maintain out-of-equilibrium organization in virtually all living things. Often this takes the form of converting the free energy stored in nonequilibrium chemical potential differences…

Statistical Mechanics · Physics 2019-08-23 Steven J. Large , David A. Sivak

In an effort to better understand collisionless relaxation processes in gravitational systems, we investigate one-dimensional models. Taking advantage of a Hermite-Legendre expansion of relevant distribution functions, we present analytical…

Astrophysics of Galaxies · Physics 2019-06-12 Eric I. Barnes , Robert J. Ragan

Many non-equilibrium, active processes are observed at a coarse-grained level, where different microscopic configurations are projected onto the same observable state. Such "lumped" observables display memory, and in many cases the…

Statistical Mechanics · Physics 2024-04-29 Kristian Blom , Kevin Song , Etienne Vouga , Aljaž Godec , Dmitrii E. Makarov
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