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Related papers: Reasoning-Based Approach with Chain-of-Thought for…

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Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

Machine Learning · Computer Science 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

Computation and Language · Computer Science 2023-08-24 Loukas Ilias , Dimitris Askounis

With the remarkable success of Multimodal Large Language Models (MLLMs) in perception tasks, enhancing their complex reasoning capabilities has emerged as a critical research focus. Existing models still suffer from challenges such as…

Computation and Language · Computer Science 2025-12-01 Wenxin Zhu , Andong Chen , Yuchen Song , Kehai Chen , Conghui Zhu , Ziyan Chen , Tiejun Zhao

Chain-of-Thought (CoT) is widely applied to enhance the LLM capability in math, coding and reasoning tasks. However, its performance is limited for open-domain tasks, when there are no clearly defined reasoning steps or logical transitions.…

Computation and Language · Computer Science 2025-11-18 Qingqing Gu , Dan Wang , Yue Zhao , Xiaoyu Wang , Zhonglin Jiang , Yong Chen , Hongyan Li , Luo Ji

In the past decade, there has been a surge in research examining the use of voice and speech analysis as a means of detecting neurodegenerative diseases such as Alzheimer's. Many studies have shown that certain acoustic features can be used…

Audio and Speech Processing · Electrical Eng. & Systems 2023-07-20 Vrindha M. K. , Geethu V. , Anurenjan P. R. , Deepak S. , Sreeni K. G.

Early diagnosis of Alzheimer's Disease (AD) faces multiple data-related challenges, including high variability in patient data, limited access to specialized diagnostic tests, and overreliance on single-type indicators. These challenges are…

Quantitative Methods · Quantitative Biology 2025-03-05 Yizong Xing , Dhita Putri Pratama , Yuke Wang , Yufan Zhang , Brian E. Chapman

Recent advances in large language models (LLMs) have opened new possibilities for automated reasoning and decision-making in wireless networks. However, applying LLMs to wireless communications presents challenges such as limited capability…

Networking and Internet Architecture · Computer Science 2025-05-29 Xudong Wang , Jian Zhu , Ruichen Zhang , Lei Feng , Dusit Niyato , Jiacheng Wang , Hongyang Du , Shiwen Mao , Zhu Han

Large Language Models (LLMs) have demonstrated remarkable abilities across various language tasks, but solving complex reasoning problems remains a significant challenge. While existing methods, such as Chain-of-Thought (CoT) and…

Computation and Language · Computer Science 2025-04-02 Zhenni Bi , Kai Han , Chuanjian Liu , Yehui Tang , Yunhe Wang

Chain-of-Thought (CoT) and Program-Aided Language Models (PAL) represent two distinct reasoning methods, each with its own strengths. CoT employs natural language, offering flexibility and interpretability, while PAL utilizes programming…

Computation and Language · Computer Science 2023-10-24 James Xu Zhao , Yuxi Xie , Kenji Kawaguchi , Junxian He , Michael Qizhe Xie

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

Large language models (LLMs) can perform complex reasoning by generating intermediate reasoning steps. Providing these steps for prompting demonstrations is called chain-of-thought (CoT) prompting. CoT prompting has two major paradigms. One…

Computation and Language · Computer Science 2022-10-10 Zhuosheng Zhang , Aston Zhang , Mu Li , Alex Smola

Large Language Models (LLMs) have shown impressive performance in complex reasoning tasks through the use of Chain-of-Thought (CoT) reasoning, allowing models to break down problems into manageable sub-tasks. However, existing CoT…

Computation and Language · Computer Science 2025-07-11 Jean-Francois Ton , Muhammad Faaiz Taufiq , Yang Liu

While Long Chain-of-Thought (CoT) reasoning significantly improves Large Language Models (LLMs) performance on complex reasoning tasks, the substantial computational and memory costs of generating long CoT sequences limit their efficiency…

Artificial Intelligence · Computer Science 2026-02-03 Liang Zhang , Yu Zhao , Longyue Wang , Tianqi Shi , Weihua Luo , Kaifu Zhang , Jinsong Su

Chain-of-Thought (CoT) prompting can enhance the reasoning capabilities of large language models (LLMs), establishing itself as a primary approach to solving complex reasoning tasks. Existing CoT synthesis approaches usually focus on…

Computation and Language · Computer Science 2024-03-22 Xiaoxue Cheng , Junyi Li , Wayne Xin Zhao , Ji-Rong Wen

Large language models (LLMs) face significant challenges in specialized biomedical tasks due to the inherent complexity of medical reasoning and the sensitive nature of clinical data. Existing LLMs often struggle with intricate medical…

Computation and Language · Computer Science 2026-05-12 Zongxian Yang , Jiayu Qian , Kay Chen Tan , Hau-San Wong , Yulong Chen , Haoyu Zhang , Zhi-An Huang

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and to delay further progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical…

Computation and Language · Computer Science 2023-04-03 Yi Wang , Jiajun Deng , Tianzi Wang , Bo Zheng , Shoukang Hu , Xunying Liu , Helen Meng

Recent studies have discovered that Chain-of-Thought prompting (CoT) can dramatically improve the performance of Large Language Models (LLMs), particularly when dealing with complex tasks involving mathematics or reasoning. Despite the…

Machine Learning · Computer Science 2023-12-27 Guhao Feng , Bohang Zhang , Yuntian Gu , Haotian Ye , Di He , Liwei Wang

Complex numerical time series analysis often demands multi-step reasoning capabilities beyond current models' reach. Tasks like medical diagnosis and weather forecasting require sequential reasoning processes - including counterfactual…

Machine Learning · Computer Science 2026-03-17 Felix Parker , Nimeesha Chan , Chi Zhang , Kimia Ghobadi

Chain-of-Thought (CoT) is a critical technique in enhancing the reasoning ability of Large Language Models (LLMs), and latent reasoning methods have been proposed to accelerate the inefficient token-level reasoning chain. We notice that…

Computation and Language · Computer Science 2026-02-05 Fangwei Zhu , Zhifang Sui

Large language models (LLMs) have emerged as powerful tools for medical information retrieval, yet their accuracy and depth remain limited in specialized domains such as Alzheimer's disease (AD), a growing global health challenge. To…