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Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Human multimodal emotion recognition (MER) aims to perceive human emotions via language, visual and acoustic modalities. Despite the impressive performance of previous MER approaches, the inherent multimodal heterogeneities still haunt and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Yong Li , Yuanzhi Wang , Zhen Cui

Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

Machine Learning · Computer Science 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

The increasing availability and diversity of multimodal data in recommender systems offer new avenues for enhancing recommendation accuracy and user satisfaction. However, these systems must contend with high-dimensional, sparse user-item…

Information Retrieval · Computer Science 2024-12-04 Yasser Khalafaoui , Martino Lovisetto , Basarab Matei , Nistor Grozavu

The precise subtype classification of myeloproliferative neoplasms (MPNs) based on multimodal information, which assists clinicians in diagnosis and long-term treatment plans, is of great clinical significance. However, it remains a great…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Yuan Zhang , Yaolei Qi , Xiaoming Qi , Yongyue Wei , Guanyu Yang

Identification of brain regions related to the specific neurological disorders are of great importance for biomarker and diagnostic studies. In this paper, we propose an interpretable Graph Convolutional Network (GCN) framework for the…

Machine Learning · Computer Science 2022-04-29 Houliang Zhou , Lifang He , Yu Zhang , Li Shen , Brian Chen

Drug combination therapy has become a increasingly promising method in the treatment of cancer. However, the number of possible drug combinations is so huge that it is hard to screen synergistic drug combinations through wet-lab…

Machine Learning · Computer Science 2021-07-07 J. Wang , X. Liu , S. Shen , L. Deng , H. Liu*

Alzheimer's disease (AD) is a common neurodegenerative disease among the elderly. Early prediction and timely intervention of its prodromal stage, mild cognitive impairment (MCI), can decrease the risk of advancing to AD. Combining…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Xiangyang Hu , Xiangyu Shen , Yifei Sun , Xuhao Shan , Wenwen Min , Liyilei Su , Xiaomao Fan , Ahmed Elazab , Ruiquan Ge , Changmiao Wang , Xiaopeng Fan

This paper describes a multi-modal approach for the automatic detection of Alzheimer's disease proposed in the context of the INESC-ID Human Language Technology Laboratory participation in the ADReSS 2020 challenge. Our classification…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-01 Anna Pompili , Thomas Rolland , Alberto Abad

A comprehensive view of factors associated with AD/ADRD will significantly aid in studies to develop new treatments for AD/ADRD and identify high-risk populations and patients for prevention efforts. In our study, we summarized the risk…

Artificial Intelligence · Computer Science 2024-02-27 Aokun Chen , Qian Li , Yu Huang , Yongqiu Li , Yu-neng Chuang , Xia Hu , Serena Guo , Yonghui Wu , Yi Guo , Jiang Bian

Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Yexiao He , Ziyao Wang , Yuning Zhang , Tingting Dan , Tianlong Chen , Guorong Wu , Ang Li

Multimodal multi-label emotion recognition (MMER) aims to identify the concurrent presence of multiple emotions in multimodal data. Existing studies primarily focus on improving fusion strategies and modeling modality-to-label dependencies.…

Computation and Language · Computer Science 2025-02-20 Jingwang Huang , Jiang Zhong , Qin Lei , Jinpeng Gao , Yuming Yang , Sirui Wang , Peiguang Li , Kaiwen Wei

Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Mohammad Rafsan , Tamer Oraby , Upal Roy , Sanjeev Kumar , Hansapani Rodrigo

For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining…

Machine Learning · Statistics 2019-03-06 Stefan Konigorski , Shahryar Khorasani , Christoph Lippert

Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…

Image and Video Processing · Electrical Eng. & Systems 2023-11-23 Guian Fang , Mengsha Liu , Yi Zhong , Zhuolin Zhang , Jiehui Huang , Zhenchao Tang , Calvin Yu-Chian Chen

Accurately predicting molecular properties is a challenging but essential task in drug discovery. Recently, many mono-modal deep learning methods have been successfully applied to molecular property prediction. However, the inherent…

Machine Learning · Computer Science 2024-09-16 Xiaohua Lu , Liangxu Xie , Lei Xu , Rongzhi Mao , Shan Chang , Xiaojun Xu

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

We present a novel unsupervised deep learning framework for anomalous event detection in complex video scenes. While most existing works merely use hand-crafted appearance and motion features, we propose Appearance and Motion DeepNet (AMDN)…

Computer Vision and Pattern Recognition · Computer Science 2015-10-07 Dan Xu , Elisa Ricci , Yan Yan , Jingkuan Song , Nicu Sebe

Biomarker discovery in neurodegenerative diseases requires robust, interpretable frameworks capable of integrating high-dimensional multi-omics data under low-sample conditions. We propose a novel ensemble approach combining Graph Attention…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Byeonghee Lee , Joonsung Kang

Human multimodal emotion recognition (MER) seeks to infer human emotions by integrating information from language, visual, and acoustic modalities. Although existing MER approaches have achieved promising results, they still struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Yong Li , Yuanzhi Wang , Yi Ding , Shiqing Zhang , Ke Lu , Cuntai Guan