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In this work, we present a fundamental mathematical model for proton transport, tailored to capture the key physical processes underpinning Proton Beam Therapy (PBT). The model provides a robust and computationally efficient framework for…

This work develops a rigorous mathematical formulation of proton transport by integrating both deterministic and stochastic perspectives. The deterministic framework is based on the Boltzmann-Fokker-Planck equation, formulated as an…

Probability · Mathematics 2025-08-15 Andreas E. Kyprianou , Aaron Pim , Tristan Pryer

In this thesis we develop a stabilised finite element method for solving the equations of poroelasticity to enable solving complex models of biological tissues such as the human lungs. For the proposed numerical scheme, we use the lowest…

Numerical Analysis · Mathematics 2016-09-23 Lorenz Berger

A dynamic linear thermo-poroelasticity model, containing inertial and relaxation terms with second-order time derivatives, is investigated in this paper. The mathematical and numerical analysis of this model is performed in the frequency…

Numerical Analysis · Mathematics 2025-11-25 Hongpeng Li , Cristian Carcamo , Hongxing Rui , Volker John

A coarse-grained computational procedure based on the Finite Element Method is proposed to calculate the normal modes and mechanical response of proteins and their supramolecular assemblies. Motivated by the elastic network model, proteins…

Biomolecules · Quantitative Biology 2007-05-23 Mark Bathe

We present a finite element discretisation to model the interaction between a poroelastic structure and an elastic medium. The consolidation problem considers fully coupled deformations across an interface, ensuring continuity of…

Numerical Analysis · Mathematics 2023-06-21 S. Badia , M. Hornkjøl , A. Khan , K. -A. Mardal , A. F. Martín , R. Ruiz-Baier

We present a deterministic framework for proton therapy dose calculation based on finite element discretizations of the energy-dependent $M_1$ moment model. The nonlinear $M_1$ system is derived from the Fokker--Planck equation for charged…

Numerical Analysis · Mathematics 2026-03-12 Paul Moujaes , Dmitri Kuzmin , Christian Bäumer

We propose a numerical strategy to generate the anisotropic meshes and select the appropriate stabilized parameters simultaneously for two dimensional convection-dominated convection-diffusion equations by stabilized continuous linear…

Numerical Analysis · Mathematics 2016-02-09 Yana Di , Hehu Xie , Xiaobo Yin

This article presents a new finite element method for convection-diffusion equations by enhancing the continuous finite element space with a flux space for flux approximations that preserve the important mass conservation locally on each…

Numerical Analysis · Mathematics 2017-10-24 Yujie Liu , Junping Wang , Qingsong Zou

A finite element formulation is developed for a poroelastic medium consisting of an incompressible hyperelastic skeleton saturated by an incompressible fluid. The governing equations stem from mixture theory and the application is motivated…

Numerical Analysis · Mathematics 2016-10-04 Francesco Costanzo , Scott T. Miller

In this paper, we propose a nonlinear positivity-preserving finite volume element(FVE) scheme for anisotropic diffusion problems on quadrilateral meshes. Based on an overlapping dual partition, the one-sided flux is approximated by the…

Numerical Analysis · Mathematics 2019-02-14 Yanni Gao , Guangwei Yuan , Shuai Wang , Xudeng Hang

In this work, we present the construction of two distinct finite element approaches to solve the Porous Medium Equation (PME). In the first approach, we transform the PME to a log-density variable formulation and construct a continuous…

Numerical Analysis · Mathematics 2023-03-28 Arjun Vijaywargiya , Guosheng Fu

We consider a prototypical parabolic SPDE with finite-dimensional multiplicative noise, which, subject to a nonnegative initial datum, has a unique nonnegative solution. Inspired by well-established techniques in the deterministic case, we…

Numerical Analysis · Mathematics 2026-04-10 Ana Djurdjevac , Claude Le Bris , Endre Süli

The finite element method is one of the widely employed numerical techniques in electrical engineering for the study of electric and magnetic fields. When applied to the moving conductor problems, the finite element method is known to have…

Numerical Analysis · Mathematics 2022-09-01 Sethupathy Subramanian , Sujata Bhowmick

We introduce a (linear) positive and asymptotic preserving method or solving the one-group radiation transport equation. The approximation in space is discretization agnostic: the space approximation can be done with continuous or…

Numerical Analysis · Mathematics 2019-05-10 Jean-Luc Guermond , Bojan Popov , Jean Ragusa

We present a positive and asymptotic preserving numerical scheme for solving linear kinetic, transport equations that relax to a diffusive equation in the limit of infinite scattering. The proposed scheme is developed using a standard…

Numerical Analysis · Mathematics 2018-07-18 M. Paul Laiu , Martin Frank , Cory D. Hauck

In this paper, we propose a new formulation and a suitable finite element method for the steady coupling of viscous flow in deformable porous media using divergence-conforming filtration fluxes. The proposed method is based on the use of…

Numerical Analysis · Mathematics 2025-10-23 Ruben Caraballo , Chansophea Wathanak In , Alberto F. Martín , Ricardo Ruiz-Baier

In this paper, we propose a multiphysics finite element method for a quasi-static thermo-poroelasticity model with a nonlinear convective transport term. To design some stable numerical methods and reveal the multi-physical processes of…

Numerical Analysis · Mathematics 2023-10-10 Zhihao Ge , Dandan Xu

We propose a mathematical model that combines elastic, viscous and porous effects with growth or shrinkage due to microstructural changes. This phenomenon is important in tissue or tumor growth, as well as in dermal contraction. Although…

Numerical Analysis · Mathematics 2025-12-12 Sabia Asghar , Duncan den Bakker , Etelvina Javierre , Qiyao Peng , Fred J. Vermolen

In the present work, we investigate a model of the invasion of healthy tissue by cancer cells which is described by a system of nonlinear PDEs consisting of a cross-diffusion-reaction equation and two additional nonlinear ordinary…

Numerical Analysis · Mathematics 2023-07-18 Shahin Heydari , Petr Knobloch , Thoma Wick
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