English
Related papers

Related papers: Uncertainty-Aware Metabolic Stability Prediction w…

200 papers

Neural networks (NNs) are currently changing the computational paradigm on how to combine data with mathematical laws in physics and engineering in a profound way, tackling challenging inverse and ill-posed problems not solvable with…

Machine Learning · Computer Science 2023-02-08 Apostolos F Psaros , Xuhui Meng , Zongren Zou , Ling Guo , George Em Karniadakis

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Accurate and robust trajectory predictions of road users are needed to enable safe automated driving. To do this, machine learning models are often used, which can show erratic behavior when presented with previously unseen inputs. In this…

Artificial Intelligence · Computer Science 2023-04-05 Manuel Muñoz Sánchez , Emilia Silvas , Jos Elfring , René van de Molengraft

The widespread adoption of machine learning surrogate models has significantly improved the scale and complexity of systems and processes that can be explored accurately and efficiently using atomistic modeling. However, the inherently…

Chemical Physics · Physics 2025-03-13 Federico Grasselli , Sanggyu Chong , Venkat Kapil , Silvia Bonfanti , Kevin Rossi

Organic synthesis is one of the key stumbling blocks in medicinal chemistry. A necessary yet unsolved step in planning synthesis is solving the forward problem: given reactants and reagents, predict the products. Similar to other work, we…

Chemical Physics · Physics 2019-09-13 Philippe Schwaller , Teodoro Laino , Théophile Gaudin , Peter Bolgar , Costas Bekas , Alpha A Lee

In system analysis and design optimization, multiple computational models are typically available to represent a given physical system. These models can be broadly classified as high-fidelity models, which provide highly accurate…

Machine Learning · Computer Science 2024-11-01 Ruda Zhang , Negin Alemazkoor

To facilitate a wide-spread acceptance of AI systems guiding decision making in real-world applications, trustworthiness of deployed models is key. That is, it is crucial for predictive models to be uncertainty-aware and yield…

Machine Learning · Computer Science 2021-03-04 Christian Tomani , Florian Buettner

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

Artificial Intelligence · Computer Science 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

This paper addresses the challenges of complex dependencies and diverse anomaly patterns in cloud service environments by proposing a dependency modeling and anomaly detection method that integrates contrastive learning. The method…

Machine Learning · Computer Science 2025-10-16 Yue Xing , Yingnan Deng , Heyao Liu , Ming Wang , Yun Zi , Xiaoxuan Sun

When a machine learning model is deployed, its predictions can alter its environment, as better informed agents strategize to suit their own interests. With such alterations in mind, existing approaches to uncertainty quantification break.…

Machine Learning · Statistics 2024-11-05 Daniel Csillag , Claudio José Struchiner , Guilherme Tegoni Goedert

Transformer-based language models have set new benchmarks across a wide range of NLP tasks, yet reliably estimating the uncertainty of their predictions remains a significant challenge. Existing uncertainty estimation (UE) techniques often…

Machine Learning · Computer Science 2024-09-18 Elizaveta Kostenok , Daniil Cherniavskii , Alexey Zaytsev

Marching squares (MS) and marching cubes (MC) are widely used algorithms for level-set visualization of scientific data. In this paper, we address the challenge of uncertainty visualization of the topology cases of the MS and MC algorithms…

Graphics · Computer Science 2021-08-09 Tushar M. Athawale , Sudhanshu Sane , Chris R. Johnson

Traditional multimodal methods often assume static modality quality, which limits their adaptability in dynamic real-world scenarios. Thus, dynamical multimodal methods are proposed to assess modality quality and adjust their contribution…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Shicai Wei , Kaijie Zhang , Luyi Chen , Tao He , Guiduo Duan

In the context of image classification, Concept Bottleneck Models (CBMs) first embed images into a set of human-understandable concepts, followed by an intrinsically interpretable classifier that predicts labels based on these intermediate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Haifei Zhang , Patrick Barry , Eduardo Brandao

In the field of neuroimaging, accurate brain age prediction is pivotal for uncovering the complexities of brain aging and pinpointing early indicators of neurodegenerative conditions. Recent advancements in self-supervised learning,…

Uncertainty quantification (UQ) is an important component of molecular property prediction, particularly for drug discovery applications where model predictions direct experimental design and where unanticipated imprecision wastes valuable…

Machine Learning · Computer Science 2020-05-21 Lior Hirschfeld , Kyle Swanson , Kevin Yang , Regina Barzilay , Connor W. Coley

Accurately detecting multiple change-points is critical for various applications, but determining the optimal number of change-points remains a challenge. Existing approaches based on information criteria attempt to balance goodness-of-fit…

Methodology · Statistics 2023-12-19 Hui Chen , Yinxu Jia , Guanghui Wang , Changliang Zou

Graph neural networks (GNNs) demonstrate great performance in compound property and activity prediction due to their capability to efficiently learn complex molecular graph structures. However, two main limitations persist including…

Biomolecules · Quantitative Biology 2023-10-10 Apakorn Kengkanna , Masahito Ohue

Humans possess a finely tuned sense of uncertainty that helps anticipate potential errors, vital for adaptive behavior and survival. However, the underlying neural mechanisms remain unclear. This study applies moment neural networks (MNNs)…

Biological Physics · Physics 2024-11-22 Hengyuan Ma , Wenlian Lu , Jianfeng Feng

Deep learning has been shown to be highly effective for automatic modulation classification (AMC), which is a pivotal technology for next-generation cognitive communications. Yet, existing deep learning methods for AMC often lack robust…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Huian Yang , Rajeev Sahay