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Despite the significant progress in multimodal large language models (MLLMs), their high computational cost remains a barrier to real-world deployment. Inspired by the mixture of depths (MoDs) in natural language processing, we aim to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Yaxin Luo , Gen Luo , Jiayi Ji , Yiyi Zhou , Xiaoshuai Sun , Zhiqiang Shen , Rongrong Ji

Large Language Models (LLMs) have demonstrated remarkable performance across various natural language tasks, marking significant strides towards general artificial intelligence. While general artificial intelligence is leveraged by…

Computation and Language · Computer Science 2023-10-31 Yizhe Yang , Huashan Sun , Jiawei Li , Runheng Liu , Yinghao Li , Yuhang Liu , Heyan Huang , Yang Gao

Fine-tuning Large Language Models (LLMs) with multimodal encoders on modality-specific data expands the modalities that LLMs can handle, leading to the formation of Multimodal LLMs (MLLMs). However, this paradigm heavily relies on…

Computation and Language · Computer Science 2025-05-26 Junlin Li , Guodong DU , Jing Li , Sim Kuan Goh , Wenya Wang , Yequan Wang , Fangming Liu , Ho-Kin Tang , Saleh Alharbi , Daojing He , Min Zhang

Skeleton-based action recognition has garnered significant attention due to the utilization of concise and resilient skeletons. Nevertheless, the absence of detailed body information in skeletons restricts performance, while other…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Jinfu Liu , Chen Chen , Mengyuan Liu

Since the release of ChatGPT and GPT-4, large language models (LLMs) and multimodal large language models (MLLMs) have attracted widespread attention for their exceptional capabilities in understanding, reasoning, and generation,…

Computation and Language · Computer Science 2024-12-31 Hanguang Xiao , Feizhong Zhou , Xingyue Liu , Tianqi Liu , Zhipeng Li , Xin Liu , Xiaoxuan Huang

Utilizing Large Language Models (LLMs) for complex tasks is challenging, often involving a time-consuming and uncontrollable prompt engineering process. This paper introduces a novel human-LLM interaction framework, Low-code LLM. It…

Computation and Language · Computer Science 2024-04-02 Yuzhe Cai , Shaoguang Mao , Wenshan Wu , Zehua Wang , Yaobo Liang , Tao Ge , Chenfei Wu , Wang You , Ting Song , Yan Xia , Jonathan Tien , Nan Duan , Furu Wei

Large Language Models (LLMs) have shown great promise in multilingual machine translation (MT), even with limited bilingual supervision. However, fine-tuning LLMs with parallel corpora presents major challenges, namely parameter…

Computation and Language · Computer Science 2026-05-26 Bo Li , Tianyu Dong , Shaolin Zhu , Deyi Xiong

Multi-modal large language models (MLLMs) have rapidly advanced in visual tasks, yet their spatial understanding remains limited to single images, leaving them ill-suited for physical-world applications that require multi-frame reasoning.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Runsen Xu , Weiyao Wang , Hao Tang , Xingyu Chen , Xiaodong Wang , Fu-Jen Chu , Matt Feiszli , Kevin J. Liang

Proteins are essential macromolecules defined by their amino acid sequences, which determine their three-dimensional structures and, consequently, their functions in all living organisms. Therefore, generative protein modeling necessitates…

Machine Learning · Computer Science 2024-10-18 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

Molecular dynamics (MD) simulations are essential for understanding biomolecular systems but remain challenging to automate. Recent advances in large language models (LLM) have demonstrated success in automating complex scientific tasks…

Artificial Intelligence · Computer Science 2025-02-14 Quintina Campbell , Sam Cox , Jorge Medina , Brittany Watterson , Andrew D. White

Large Language Models (LLMs) possess human-level cognitive and decision-making capabilities, making them a key technology for 6G. However, applying LLMs to the communication domain faces three major challenges: 1) Inadequate communication…

Information Theory · Computer Science 2025-02-27 Feibo Jiang , Wanyun Zhu , Li Dong , Kezhi Wang , Kun Yang , Cunhua Pan , Octavia A. Dobre

Conducting a comprehensive literature review is crucial for advancing circuit design methodologies. However, the rapid influx of state-of-the-art research, inconsistent data representation, and the complexity of optimizing circuit design…

Machine Learning · Computer Science 2025-08-12 Pravallika Abbineni , Saoud Aldowaish , Colin Liechty , Soroosh Noorzad , Ali Ghazizadeh , Morteza Fayazi

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

Understanding and continuously refining multimodal molecular knowledge is crucial for advancing biomedicine, chemistry, and materials science. Molecule language models (MoLMs) have become powerful tools in these domains, integrating…

Machine Learning · Computer Science 2025-12-01 Zhenyu Lei , Patrick Soga , Yaochen Zhu , Yinhan He , Yushun Dong , Jundong Li

In an era defined by the explosive growth of data and rapid technological advancements, Multimodal Large Language Models (MLLMs) stand at the forefront of artificial intelligence (AI) systems. Designed to seamlessly integrate diverse data…

Multimodal Large Language Models (MLLMs) have made impressive progress in connecting vision and language, but they still struggle with spatial understanding and viewpoint-aware reasoning. Recent efforts aim to augment the input…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Kevin Qu , Haozhe Qi , Mihai Dusmanu , Mahdi Rad , Rui Wang , Marc Pollefeys

Artificial intelligence (AI) is reshaping computational and network biology by enabling new approaches to decode cellular communication networks. We introduce Hierarchical Molecular Language Models (HMLMs), a novel framework that models…

Molecular Networks · Quantitative Biology 2025-12-16 Hasi Hays , Yue Yu , William J. Richardson

Multimodal protein language models (PLMs) integrate sequence and token-based structural information, serving as a powerful foundation for protein modeling, generation, and design. However, the reliance on tokenizing 3D structures into…

Machine Learning · Computer Science 2025-06-13 Cheng-Yen Hsieh , Xinyou Wang , Daiheng Zhang , Dongyu Xue , Fei Ye , Shujian Huang , Zaixiang Zheng , Quanquan Gu

Integrating large language models (LLMs) with knowledge graphs derived from domain-specific data represents an important advancement towards more powerful and factual reasoning. As these models grow more capable, it is crucial to enable…

Artificial Intelligence · Computer Science 2024-04-19 Stefan Dernbach , Khushbu Agarwal , Alejandro Zuniga , Michael Henry , Sutanay Choudhury

Although Large Language Models (LLMs) excel in reasoning and generation for language tasks, they are not specifically designed for multimodal challenges. Training Multimodal Large Language Models (MLLMs), however, is resource-intensive and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Yuqi Pang , Bowen Yang , Haoqin Tu , Yun Cao , Zeyu Zhang
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