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Genomic Foundation Models (GFMs), such as Evolutionary Scale Modeling (ESM), have demonstrated remarkable success in variant effect prediction. However, their security and robustness under adversarial manipulation remain largely unexplored.…

Cryptography and Security · Computer Science 2025-12-22 Huixin Zhan

We propose the first unified adversarial attack benchmark for Genomic Foundation Models (GFMs), named GenoArmory. Unlike existing GFM benchmarks, GenoArmory offers the first comprehensive evaluation framework to systematically assess the…

Machine Learning · Computer Science 2025-10-14 Haozheng Luo , Chenghao Qiu , Yimin Wang , Shang Wu , Jiahao Yu , Zhenyu Pan , Weian Mao , Haoyang Fang , Hao Xu , Han Liu , Binghui Wang , Yan Chen

Adversarial attacks, particularly the Fast Gradient Sign Method (FGSM) and Projected Gradient Descent (PGD) pose significant threats to the robustness of deep learning models in image classification. This paper explores and refines defense…

Cryptography and Security · Computer Science 2025-05-15 Hetvi Waghela , Jaydip Sen , Sneha Rakshit

The nature of deep neural networks has given rise to a variety of attacks, but little work has been done to address the effect of adversarial attacks on segmentation models trained on MRI datasets. In light of the grave consequences that…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Zhongxuan Wang , Leo Xu

The Genomic Foundation Model (GFM) paradigm is expected to facilitate the extraction of generalizable representations from massive genomic data, thereby enabling their application across a spectrum of downstream applications. Despite…

Genomics · Quantitative Biology 2024-06-06 Zicheng Liu , Jiahui Li , Siyuan Li , Zelin Zang , Cheng Tan , Yufei Huang , Yajing Bai , Stan Z. Li

Time-Series Foundation Models (TSFMs) are rapidly transitioning from research prototypes to core components of critical decision-making systems, driven by their impressive zero-shot forecasting capabilities. However, as their deployment…

Machine Learning · Computer Science 2025-12-09 Jiawen Zhang , Zhenwei Zhang , Shun Zheng , Xumeng Wen , Jia Li , Jiang Bian

Graph Foundation Models (GFMs) are pre-trained on diverse source domains and adapted to unseen targets, enabling broad generalization for graph machine learning. Despite that GFMs have attracted considerable attention recently, their…

Cryptography and Security · Computer Science 2025-11-25 Jiayi Luo , Qingyun Sun , Lingjuan Lyu , Ziwei Zhang , Haonan Yuan , Xingcheng Fu , Jianxin Li

Generating adversarial examples at scale is a core primitive for robustness evaluation, adversarial training, and red-teaming, yet even "fast" attacks such as FGSM remain throughput-limited by the cost of a backward pass. We introduce a…

Machine Learning · Computer Science 2026-05-15 Kamil Ciosek , Aleksandr V. Petrov , Nicolò Felicioni , Konstantina Palla

Malware detection models based on deep learning have been widely used, but recent research shows that deep learning models are vulnerable to adversarial attacks. Adversarial attacks are to deceive the deep learning model by generating…

Cryptography and Security · Computer Science 2023-05-23 Kun Li , Fan Zhang , Wei Guo

This paper examines the vulnerabilities of convolutional neural networks (CNNs) to adversarial attacks and explores a method for their safeguarding. In this study, CNNs were implemented on four of the most common image datasets, namely…

Machine Learning · Computer Science 2025-02-11 Koushik Chowdhury

Model fingerprinting has emerged as a promising paradigm for claiming model ownership. However, robustness evaluations of these schemes have mostly focused on benign perturbations such as incremental fine-tuning, model merging, and…

Cryptography and Security · Computer Science 2025-10-01 Anshul Nasery , Edoardo Contente , Alkin Kaz , Pramod Viswanath , Sewoong Oh

With the steady rise of the use of AI in bio-technical applications and the widespread adoption of genomics sequencing, an increasing amount of AI-based algorithms and tools is entering the research and production stage affecting critical…

Machine Learning · Computer Science 2024-01-22 Heorhii Skovorodnikov , Hoda Alkhzaimi

This paper investigates the resilience of a ResNet-50 image classification model under two prominent security threats: Fast Gradient Sign Method (FGSM) adversarial attacks and malicious payload injection. Initially, the model attains a…

Cryptography and Security · Computer Science 2025-01-22 Umesh Yadav , Suman Niroula , Gaurav Kumar Gupta , Bicky Yadav

Deep convolutional neural network (DCNN for short) models are vulnerable to examples with small perturbations. Adversarial training (AT for short) is a widely used approach to enhance the robustness of DCNN models by data augmentation. In…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Jin Ding , Jie-Chao Zhao , Yong-Zhi Sun , Ping Tan , Ji-En Ma , You-Tong Fang

Biometric authentication methods, representing the "something you are" scheme, are considered the most secure approach for gaining access to protected resources. Recent attacks using Machine Learning techniques demand a serious systematic…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Arbena Musa , Kamer Vishi , Blerim Rexha

Graph machine learning has advanced rapidly in tasks such as link prediction, anomaly detection, and node classification. As models scale up, pretrained graph models have become valuable intellectual assets because they encode extensive…

The emergence of deep learning models has revolutionized various industries over the last decade, leading to a surge in connected devices and infrastructures. However, these models can be tricked into making incorrect predictions with high…

Machine Learning · Computer Science 2025-09-03 Pooja Krishan , Rohan Mohapatra , Sanchari Das , Saptarshi Sengupta

Prompt injection attacks pose a significant challenge to the safe deployment of Large Language Models (LLMs) in real-world applications. While prompt-based detection offers a lightweight and interpretable defense strategy, its effectiveness…

Cryptography and Security · Computer Science 2025-10-10 Ting-Chun Liu , Ching-Yu Hsu , Kuan-Yi Lee , Chi-An Fu , Hung-yi Lee

Current genomic foundation models (GFMs) rely on extensive neural computation to implicitly approximate conserved biological motifs from single-nucleotide inputs. We propose Gengram, a conditional memory module that introduces an explicit…

The notion of adversarial attacks on image classification models based on convolutional neural networks (CNN) is introduced in this work. To classify images, deep learning models called CNNs are frequently used. However, when the networks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Jaydip Sen , Abhiraj Sen , Ananda Chatterjee
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