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Multimodal large language models have advanced rapidly, but their adoption in medicine is constrained by limited domain coverage, imperfect modality alignment, and insufficient grounded reasoning. We introduce MedMO, a medical multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ankan Deria , Komal Kumar , Adinath Madhavrao Dukre , Eran Segal , Salman Khan , Imran Razzak

Recent advances in large language models (LLMs) have shown strong reasoning capabilities through large-scale pretraining and post-training reinforcement learning, demonstrated by DeepSeek-R1. However, current post-training methods, such as…

Artificial Intelligence · Computer Science 2025-12-04 Boyang Gu , Hongjian Zhou , Bradley Max Segal , Jinge Wu , Zeyu Cao , Hantao Zhong , Lei Clifton , Fenglin Liu , David A. Clifton

In medical visual question answering (Med-VQA), achieving accurate responses relies on three critical steps: precise perception of medical imaging data, logical reasoning grounded in visual input and textual questions, and coherent answer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Songtao Jiang , Yuan Wang , Ruizhe Chen , Yan Zhang , Ruilin Luo , Bohan Lei , Sibo Song , Yang Feng , Jimeng Sun , Jian Wu , Zuozhu Liu

Recent advances in reinforcement learning with verifiable, rule-based rewards have greatly enhanced the reasoning capabilities and out-of-distribution generalization of VLMs/LLMs, obviating the need for manually crafted reasoning chains.…

Artificial Intelligence · Computer Science 2025-05-27 Shaohao Rui , Kaitao Chen , Weijie Ma , Xiaosong Wang

Vision-language models (VLMs) have achieved impressive progress in natural image reasoning, yet their potential in medical imaging remains underexplored. Medical vision-language tasks demand precise understanding and clinically coherent…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yuxiang Lai , Jike Zhong , Ming Li , Shitian Zhao , Yuheng Li , Konstantinos Psounis , Xiaofeng Yang

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Integrating large language models (LLMs) into healthcare holds great potential but faces challenges. Pre-training LLMs from scratch for domains like medicine is resource-heavy and often unfeasible. On the other hand, sole reliance on…

Computation and Language · Computer Science 2024-04-18 Qichen Ye , Junling Liu , Dading Chong , Peilin Zhou , Yining Hua , Fenglin Liu , Meng Cao , Ziming Wang , Xuxin Cheng , Zhu Lei , Zhenhua Guo

We present Gazal-R1, a 32-billion-parameter language model that achieves state-of-the-art performance in medical reasoning while providing transparent, step-by-step explanations for clinical decision-making. Built upon Qwen3 32B, our model…

Computation and Language · Computer Science 2025-06-30 Ahmed M. Adly , Mostafa Samy , Amr Fawzy

Vision-Language Models (VLMs) show promise in medical image analysis, yet their capacity for structured reasoning in complex domains like dermatology is often limited by data scarcity and the high computational cost of advanced training…

Computation and Language · Computer Science 2025-10-03 Ismam Nur Swapnil , Aranya Saha , Tanvir Ahmed Khan , Mohammad Ariful Haque

Multimodal Large Language Models (MLLMs) have gained significant traction for their ability to process diverse input data types and generate coherent, contextually relevant outputs across various applications. While supervised fine-tuning…

Machine Learning · Computer Science 2025-03-31 Zhiyuan Liu , Yuting Zhang , Feng Liu , Changwang Zhang , Ying Sun , Jun Wang

Medical artificial intelligence systems have achieved remarkable diagnostic capabilities, yet they consistently exhibit performance disparities across demographic groups, causing real-world harm to underrepresented populations. While recent…

Machine Learning · Computer Science 2025-10-24 Shiqi Dai , Wei Dai , Jiaee Cheong , Paul Pu Liang

Medical image quality assessment (Med-IQA) is a prerequisite for clinical AI deployment, yet multimodal large language models (MLLMs) still fall substantially short of human experts, particularly when required to provide descriptive…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Jiyao Liu , Junzhi Ning , Wanying Qu , Lihao Liu , Chenglong Ma , Junjun He , Ningsheng Xu

In medical scenarios, effectively retrieving external knowledge and leveraging it for rigorous logical reasoning is of significant importance. Despite their potential, existing work has predominantly focused on enhancing either retrieval or…

Computation and Language · Computer Science 2026-01-21 Keer Lu , Zheng Liang , Youquan Li , Jiejun Tan , Xili Wang , Da Pan , Shusen Zhang , Guosheng Dong , Bin Cui , Yunhuai Liu , Wentao Zhang

Large Language Models (LLMs) show potential in medicine, yet clinical adoption is hindered by concerns over factual accuracy, language-specific limitations (e.g., Japanese), and critically, their reliability when required to generate…

Computation and Language · Computer Science 2025-04-28 Wataru Kawakami , Keita Suzuki , Junichiro Iwasawa

The diagnosis of pathological images is often limited by expert availability and regional disparities, highlighting the importance of automated diagnosis using Vision-Language Models (VLMs). Traditional multimodal models typically emphasize…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Jianyu Wu , Hao Yang , Xinhua Zeng , Guibing He , Zhiyu Chen , Zihui Li , Xiaochuan Zhang , Yangyang Ma , Run Fang , Yang Liu

Recently, reinforcement learning (RL)-based tuning has shifted the trajectory of Multimodal Large Language Models (MLLMs), particularly following the introduction of Group Relative Policy Optimization (GRPO). However, directly applying it…

Computation and Language · Computer Science 2025-05-21 Wenhui Zhu , Xuanzhao Dong , Xin Li , Peijie Qiu , Xiwen Chen , Abolfazl Razi , Aris Sotiras , Yi Su , Yalin Wang

Traditional Chinese Medicine (TCM) presents a rich and structurally unique knowledge system that challenges conventional applications of large language models (LLMs). Although previous TCM-specific LLMs have shown progress through…

Computation and Language · Computer Science 2025-10-21 Jiacheng Xie , Shuai Zeng , Yang Yu , Xiaoting Tang , Guanghui An , Dong Xu

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Recently, large models have shown significant potential for smart healthcare. However, the deployment of Large Vision-Language Models (LVLMs) for clinical services is currently hindered by three critical challenges: a tendency to…

Artificial Intelligence · Computer Science 2025-10-27 Siyong Chen , Jinbo Wen , Jiawen Kang , Tenghui Huang , Xumin Huang , Yuanjia Su , Hudan Pan , Zishao Zhong , Dusit Niyato , Shengli Xie , Dong In Kim

Large vision-language models struggle with medical video understanding, where spatial precision, temporal reasoning, and clinical semantics are critical. To address this, we first introduce \textbf{MedVidBench}, a large-scale benchmark of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Yuhao Su , Anwesa Choudhuri , Zhongpai Gao , Benjamin Planche , Van Nguyen Nguyen , Meng Zheng , Yuhan Shen , Arun Innanje , Terrence Chen , Ehsan Elhamifar , Ziyan Wu
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