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Experiments by Chretien and co-workers suggest that mitochondria are 10oC hotter than their surroundings. Steady-state theoretical estimates place this difference at a maximum of 10^-5 oC. This million-fold disagreement may be called the…

Biological Physics · Physics 2021-12-28 Peyman Fahimi , Cherif F. Matta

In a 2018 paper and a subsequent article published in 2023, researchers reported that mitochondria maintain temperatures 10-15 degrees celsius higher than the surrounding cytoplasm - a finding that deviates by 5 to 6 orders of magnitude…

Subcellular Processes · Quantitative Biology 2025-12-05 Peyman Fahimi , Michael Lynch , Cherif F. Matta

Temperature is one of the most relevant parameters for the regulation of intracellular processes. Measuring localized subcellular temperature gradients is fundamental for a deeper understanding of cell function, such as the genesis of…

Neurons and Cognition · Quantitative Biology 2022-08-04 G. Petrini , G. Tomagra , E. Bernardi , E. Moreva , P. Traina , A. Marcantoni , F. Picollo , K. Kvakova , P. Cigler , I. P. Degiovanni , V. Carabelli , M. Genovese

A production of heat by mitochondria is critical for maintaining body temperature, regulating metabolic rate and preventing oxidative damage to mitochondria and cells. Up to now mitochondrion heat production was characterized only by…

Biological Physics · Physics 2022-11-11 A. M. Romshin , A. A. Osypov , I. Yu. Popova , V. E. Zeeb , A. G. Sinogeykin , I. I. Vlasov

The influence of temperature on neuronal excitability is studied by numerical simulations on the spiking threshold characteristics of bushy cells in cochlear nucleus periodically stimulated by synaptic currents. The results reveal that…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ting Zeng , Jiafu Wang , Shenbing Kuang

Neuronal cells change their growth properties in response to external physical stimuli such as variations in external temperature, stiffness of the growth substrate, or topographical guidance cues. Detailed knowledge of the mechanisms that…

Biological Physics · Physics 2013-10-10 Elise Spedden , David L. Kaplan , Cristian Staii

Fluorescent nanothermometry has revealed pronounced intracellular temperature heterogeneity, establishing the field of single-cell thermal biology. However, these observations have sparked a controversy known as the "10^5 gap issue",…

This paper presents a comprehensive computer simulation of thermal processes in multilayered biological tissues for the analysis of luminance temperature distributions recorded by microwave radiometry. A mathematical model combining the…

Biological Physics · Physics 2025-10-21 Maxim V. Polyakov , Illarion E. Popov

Based on the PubMed database, there are around 260 manuscripts describing nanothermometers. These research articles detail the synthesis, performance, and application of intracellular nanothermometers. This intracellular prevalence is due…

We investigate the uncertainties affecting the temperature profiles of dense cores of interstellar clouds. In regions shielded from external ultraviolet radiation, the problem is reduced to the balance between cosmic ray heating, line…

Astrophysics of Galaxies · Physics 2015-05-30 M. Juvela , N. Ysard

Almost a century ago, Johnson and Nyquist presented evidence of fluctuating electrical current and the governing fluctuation dissipation theorem (FDT). Whether, likewise, temperature T can fluctuate is a controversial topic and has led to…

Mesoscale and Nanoscale Physics · Physics 2019-04-11 Bayan Karimi , Fredrik Brange , Peter Samuelsson , Jukka P. Pekola

The temperature dependence of the steady-state fluorescence spectrum of anthracene crystals range from 300K to 500K had been investigated, which was in the temperature range of most tabletop laser-driven shock wave experiments. The…

Applied Physics · Physics 2019-08-06 Cheng Tang , Xiaojun Zhu , Yunfei Song , Weilong Liu , Qingxin Yang , Zhe lv , Yanqiang Yang

Early recordings of nervous conduction revealed a notable thermal signature associated with the electrical signal. The observed production and subsequent absorption of heat arise from physicochemical processes that occur at the cell…

Biological Physics · Physics 2020-02-19 Aymar C. L. de Lichtervelde , J. Pedro de Souza , Martin Z. Bazant

Temperature sensing is a ubiquitous cell behavior, but the fundamental limits to the precision of temperature sensing are poorly understood. Unlike in chemical concentration sensing, the precision of temperature sensing is not limited by…

Biological Physics · Physics 2021-09-01 Michael Vennettilli , Soutick Saha , Ushasi Roy , Andrew Mugler

Native membranes of biological cells display melting transitions of their lipids at a temperature of 10-20 degrees below body temperature. Such transitions can be observed in various bacterial cells, in nerves, in cancer cells, but also in…

Biological Physics · Physics 2020-08-10 Thomas Heimburg

We investigate the permeability of lipid membranes for fluorescence dyes and ions. We find that permeability reaches a maximum close to the chain melting transition of the membranes. Close to transitions, fluctuations in area and…

The temperature distribution inside a double-cladding optical fiber laser or amplifier is examined in detail. Traditionally, the quantum defect in the core is taken to be the main source of heating in an active optical fiber. However,…

Applied Physics · Physics 2020-06-24 Arash Mafi

The fluorescence detection of ultra high energy cosmic rays requires a detailed knowledge of the fluorescence light emission from nitrogen molecules over a wide range of atmospheric parameters, corresponding to altitudes typical of the…

Astrophysics · Physics 2019-08-13 M. Ave

Biologically driven non-equilibrium fluctuations are often characterized by their non-Gaussianity or by an "effective temperature", which is frequency dependent and higher than the ambient temperature. We address these two measures…

Biological Physics · Physics 2011-06-16 Eyal Ben-Isaac , YongKeun Park , Gabriel Popescu , Frank L. H. Brown , Nir S. Gov , Yair Shokef

A smartphone fluorimeter capable of time-based fluorescence intensity measurements at various temperatures is reported. Excitation is provided by an integrated UV LED (370 nm) and detection obtained using the in-built CMOS camera. A Peltier…

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