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Modern large language models (LLMs) exhibit critical vulnerabilities to poison pill attacks: localized data poisoning that alters specific factual knowledge while preserving overall model utility. We systematically demonstrate these attacks…

Cryptography and Security · Computer Science 2025-02-27 Peng Yifeng , Wu Zhizheng , Chen Chen

We show that the use of large language models (LLMs) is prevalent among crowd workers, and that targeted mitigation strategies can significantly reduce, but not eliminate, LLM use. On a text summarization task where workers were not…

Computation and Language · Computer Science 2023-10-25 Veniamin Veselovsky , Manoel Horta Ribeiro , Philip Cozzolino , Andrew Gordon , David Rothschild , Robert West

Statistical learning (SL) includes methods that extract knowledge from complex data. SL methods beyond generalized linear models are being increasingly implemented in public health research and epidemiology because they can perform better…

Large Language Models (LLMs) are increasingly utilized in autonomous decision-making, where they sample options from vast action spaces. However, the heuristics that guide this sampling process remain under explored. We study this sampling…

Computation and Language · Computer Science 2025-07-11 Sarath Sivaprasad , Pramod Kaushik , Sahar Abdelnabi , Mario Fritz

While large language models (LLMs) are increasingly being explored for mental health applications, recent studies reveal that they can exhibit stigma toward individuals with psychological conditions. Existing evaluations of this stigma…

Large-language models have recently demonstrated impressive zero-shot capabilities in a variety of natural language tasks such as summarization, dialogue generation, and question-answering. Despite many promising applications in clinical…

In domains like medicine and finance, large-scale labeled data is costly and often unavailable, leading to models trained on small datasets that struggle to generalize to real-world populations. Large language models contain extensive…

Computation and Language · Computer Science 2026-04-23 Sara Rezaeimanesh , Mohammad M. Ghassemi

Reducing hallucinations in Large Language Models (LLMs) is essential for improving the accuracy of data extraction from large text corpora. Current methods, like prompt engineering and chain-of-thought prompting, focus on individual…

Artificial Intelligence · Computer Science 2026-04-03 Daniel Xie , Maxwell J. Jacobson , Adil Wazeer , Haiyan Wang , Xinghang Zhang , Yexiang Xue

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Information Retrieval · Computer Science 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

Language models (LMs), despite their advances, often depend on spurious correlations, undermining their accuracy and generalizability. This study addresses the overlooked impact of subtler, more complex shortcuts that compromise model…

Computation and Language · Computer Science 2024-11-13 Yuqing Zhou , Ruixiang Tang , Ziyu Yao , Ziwei Zhu

Reinforcement learning (RL)-based dynamic treatment regimes (DTRs) hold promise for automating complex clinical decision-making, yet their practical deployment remains hindered by the intensive engineering required to inject clinical…

Machine Learning · Computer Science 2025-08-08 Zhiyao Luo , Tingting Zhu

Large Language Models (LLMs) are increasingly used for medical entity extraction, yet their confidence scores are often miscalibrated, limiting safe deployment in clinical settings. We present a conformal prediction framework that provides…

Computation and Language · Computer Science 2026-03-10 Manil Shrestha , Edward Kim

The reliability of machine learning systems critically assumes that the associations between features and labels remain similar between training and test distributions. However, unmeasured variables, such as confounders, break this…

Machine Learning · Computer Science 2020-08-17 Megha Srivastava , Tatsunori Hashimoto , Percy Liang

Self-supervised learning (SSL) has emerged as a powerful technique for learning rich representations from unlabeled data. The data representations are able to capture many underlying attributes of data, and be useful in downstream…

Machine Learning · Computer Science 2023-12-01 Weicheng Zhu , Sheng Liu , Carlos Fernandez-Granda , Narges Razavian

Neurological disorders that affect speech production, such as Alzheimer's Disease (AD), significantly impact the lives of both patients and caregivers, whether through social, psycho-emotional effects or other aspects not yet fully…

Large language models (LLMs) have revolutionized natural language processing and broadened their applicability across diverse commercial applications. However, the deployment of these models is constrained by high inference time in…

Computation and Language · Computer Science 2024-11-12 Euiin Yi , Taehyeon Kim , Hongseok Jeung , Du-Seong Chang , Se-Young Yun

Large language models (LLMs) are sensitive to the personas imposed on them at inference time, yet prompt-level "drug" interventions have never been benchmarked rigorously. We present the first controlled study of psychoactive framings on…

Computation and Language · Computer Science 2025-12-23 Alexander Doudkin

In machine learning, incorporating more data is often seen as a reliable strategy for improving model performance; this work challenges that notion by demonstrating that the addition of external datasets in many cases can hurt the resulting…

Machine Learning · Computer Science 2023-08-09 Rhys Compton , Lily Zhang , Aahlad Puli , Rajesh Ranganath

Although prediction models for delirium, a commonly occurring condition during general hospitalization or post-surgery, have not gained huge popularity, their algorithmic bias evaluation is crucial due to the existing association between…

Machine Learning · Computer Science 2022-11-29 Sandhya Tripathi , Bradley A Fritz , Michael S Avidan , Yixin Chen , Christopher R King

Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…