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Electronic health records (EHRs) contain a vast amount of high-dimensional multi-modal data that can accurately represent a patient's medical history. Unfortunately, most of this data is either unstructured or semi-structured, rendering it…

Computation and Language · Computer Science 2023-12-06 Ashwyn Sharma , David I. Feldman , Aneesh Jain

Left ventricular ejection fraction (LVEF) assessment depends on echocardiography, limiting access in primary care and resource-constrained settings. We developed a multimodal machine-learning framework that combines engineered 12-lead ECG…

Machine Learning · Computer Science 2026-04-30 Catherine Ning , Yu Ma , Cindy Beini Wang , Sean McMahon , Joseph Radojevic , Steven Zweibel , Dimitris Bertsimas

Heart failure (HF) discharge planning depends on identifying patients at risk of deterioration or death, yet accurate prediction from routinely collected electronic health records (EHRs) remains challenging. We developed and validated…

Low left ventricular ejection fraction (LEF) frequently remains undetected until progression to symptomatic heart failure, underscoring the need for scalable screening strategies. Although artificial intelligence-enabled electrocardiography…

Machine Learning · Computer Science 2026-04-07 Ya Zhou , Tianxiang Hao , Ziyi Cai , Haojie Zhu , Kejun He , Jia Liu , Xiaohan Fan , Jing Yuan

Biomedical research is increasingly employing real world evidence (RWE) to foster discoveries of novel clinical phenotypes and to better characterize long term effect of medical treatments. However, due to limitations inherent in the…

Machine Learning · Computer Science 2022-03-15 Jamie Wallis , Andres Azqueta-Gavaldon , Thanusha Ananthakumar , Robert Dürichen , Luca Albergante

Artificial intelligence-enabled electrocardiography (AI-ECG) can detect heart failure (HF), including disease not captured by left ventricular ejection fraction (LVEF), but the cardiac phenotypes underlying model predictions remain unclear.…

Artificial Intelligence · Computer Science 2026-05-26 Elias Stenhede , Eivind Bjørkan Orstad , Torbjørn Omland , Henrik Schirmer , Arian Ranjbar

Heart failure (HF) is one of the leading causes of rehospitalization among older adults in the United States. Although clinical notes contain rich, detailed patient information and make up a large portion of electronic health records…

Artificial Intelligence · Computer Science 2026-03-06 Rongjia Zhou , Chengzhuo Li , Carl Yang , Jiaying Lu

Heart failure (HF) is a major cause of mortality. Accurately monitoring HF progress and adjust therapies are critical for improving patient outcomes. An experienced cardiologist can make accurate HF stage diagnoses based on combination of…

Machine Learning · Computer Science 2021-03-23 Shuyu Lu , Ruoyu Chen , Wei Wei , Xinghua Lu

Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship. Identifying cancer patients at risk of heart failure (HF) is critical to improving cancer treatment outcomes and safety. This study…

Machine Learning · Computer Science 2024-11-05 Ziyi Chen , Mengyuan Zhang , Mustafa Mohammed Ahmed , Yi Guo , Thomas J. George , Jiang Bian , Yonghui Wu

Clinical machine learning research and AI driven clinical decision support models rely on clinically accurate labels. Manually extracting these labels with the help of clinical specialists is often time-consuming and expensive. This study…

Computation and Language · Computer Science 2025-05-22 Bauke Arends , Melle Vessies , Dirk van Osch , Arco Teske , Pim van der Harst , René van Es , Bram van Es

Echocardiography is a cornerstone for managing heart failure (HF), with Left Ventricular Ejection Fraction (LVEF) being a critical metric for guiding therapy. However, manual LVEF assessment suffers from high inter-observer variability,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Jyun-Ping Kao , Jiaxin Yang , C. -C. Jay Kuo , Jonghye Woo

In this paper, we proposed two different approaches, a rule-based approach and a machine-learning based approach, to identify active heart failure cases automatically by analyzing electronic health records (EHR). For the rule-based…

Computation and Language · Computer Science 2016-09-07 Shu Dong , R Kannan Mutharasan , Siddhartha Jonnalagadda

In this study, we establish a benchmark for adverse drug event (ADE) detection in Dutch clinical free-text documents using several transformer models, clinical scenarios, and fit-for-purpose performance measures. We trained a Bidirectional…

Cardiovascular diseases are a leading cause of mortality worldwide, highlighting the need for accurate diagnostic methods. This study benchmarks centralized and federated machine learning algorithms for heart disease classification using…

Machine Learning · Computer Science 2024-08-19 Mario Padilla Rodriguez , Mohamed Nafea

Recent evidence shows that deep learning models trained on electronic health records from millions of patients can deliver substantially more accurate predictions of risk compared to their statistical counterparts. While this provides an…

Hospital readmission within 30 days of discharge is a leading driver of morbidity, mortality, and avoidable healthcare expenditure in congestive heart failure (CHF). Current clinical risk stratification tools rely primarily on non-imaging…

Diagnostic or procedural coding of clinical notes aims to derive a coded summary of disease-related information about patients. Such coding is usually done manually in hospitals but could potentially be automated to improve the efficiency…

Computation and Language · Computer Science 2021-07-20 Hang Dong , Víctor Suárez-Paniagua , William Whiteley , Honghan Wu

Introduction: Chest CT scans are increasingly used in dyspneic patients where acute heart failure (AHF) is a key differential diagnosis. Interpretation remains challenging and radiology reports are frequently delayed due to a radiologist…

Accurate LVEF measurement is important in clinical practice as it identifies patients who may be in need of life-prolonging treatments. This paper presents a deep learning based framework to automatically estimate left ventricular ejection…

Image and Video Processing · Electrical Eng. & Systems 2023-04-18 Meghan Muldoon , Naimul Khan

Left ventricular ejection fraction (LVEF) is a key indicator of cardiac function and plays a central role in the diagnosis and management of cardiovascular disease. Echocardiography, as a readily accessible and non-invasive imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Shravan Saranyan , Pramit Saha
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