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In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

Machine Learning · Computer Science 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

Multimodal medical image fusion plays a crucial role in medical diagnosis by integrating complementary information from different modalities to enhance image readability and clinical applicability. However, existing methods mainly follow…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Haozhe Xiang , Han Zhang , Yu Cheng , Xiongwen Quan , Wanwan Huang

The goal of this work is to enhance balanced multimodal understanding in audio-visual large language models (AV-LLMs) by addressing modality bias without additional training. In current AV-LLMs, audio and video features are typically…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Chaeyoung Jung , Youngjoon Jang , Jongmin Choi , Joon Son Chung

Deep learning-based medical image-to-mesh reconstruction has rapidly evolved, enabling the transformation of medical imaging data into three-dimensional mesh models that are critical in computational medicine and in silico trials for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Fengming Lin , Arezoo Zakeri , Yidan Xue , Michael MacRaild , Haoran Dou , Zherui Zhou , Ziwei Zou , Ali Sarrami-Foroushani , Jinming Duan , Alejandro F. Frangi

Multi-modal medical image fusion is traditionally optimized for human visual perception, aiming to maximize generic contrast and structural fidelity. However, when these visually pleasing fused images are deployed in automated clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yuchen Guo , Junli Gong , Hongmin Cai , Yiu-ming Cheung , Weifeng Su

In cancer therapeutics, protein-metal binding mechanisms critically govern the pharmacokinetics and targeting efficacy of drugs, thereby fundamentally shaping the rational design of anticancer metallodrugs. While conventional laboratory…

Accurate lesion segmentation in ultrasound images is essential for preventive screening and clinical diagnosis, yet remains challenging due to low contrast, blurry boundaries, and significant scale variations. Although existing deep…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Chen Wang , Yixin Zhu , Yongbin Zhu , Fengyuan Shi , Qi Li , Jun Wang , Zuozhu Liu , Keli Hu

This study proposes a novel perspective on multimodal deep learning for biomedical signal classification, systematically analyzing how complementary feature domains impact model performance. While fusing multiple domains often presumes…

Machine Learning · Computer Science 2025-08-05 Timothy Oladunni , Alex Wong

Accurate segmentation of laryngo-pharyngeal tumors is crucial for precise diagnosis and effective treatment planning. However, traditional single-modality imaging methods often fall short of capturing the complex anatomical and pathological…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Junhao Wu , Yun Li , Junhao Li , Jingliang Bian , Xiaomao Fan , Wenbin Lei , Ruxin Wang

Most existing federated learning (FL) methods for medical image analysis only considered intramodal heterogeneity, limiting their applicability to multimodal imaging applications. In practice, some FL participants may possess only a subset…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Hong Liu , Dong Wei , Qian Dai , Xian Wu , Yefeng Zheng , Liansheng Wang

Deep learning has revolutionized biomedical research by providing sophisticated methods to handle complex, high-dimensional data. Multimodal deep learning (MDL) further enhances this capability by integrating diverse data types such as…

Machine Learning · Computer Science 2026-03-13 Valerio Guarrasi , Fatih Aksu , Camillo Maria Caruso , Francesco Di Feola , Aurora Rofena , Filippo Ruffini , Paolo Soda

The advent of foundation models has heralded a new era in medical artificial intelligence (AI), enabling the extraction of generalizable representations from large-scale unlabeled datasets. However, current ophthalmic AI paradigms are…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tienyu Chang , Zhen Chen , Renjie Liang , Jinyu Ding , Jie Xu , Sunu Mathew , Amir Reza Hajrasouliha , Andrew J. Saykin , Ruogu Fang , Yu Huang , Jiang Bian , Qingyu Chen

Substantial advances in multi-modal Artificial Intelligence (AI) facilitate the combination of diverse medical modalities to achieve holistic health assessments. We present COMPRER , a novel multi-modal, multi-objective pretraining…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Guy Lutsker , Hagai Rossman , Nastya Godiva , Eran Segal

Medical image segmentation is a fundamental yet challenging task due to the arduous process of acquiring large volumes of high-quality labeled data from experts. Contrastive learning offers a promising but still problematic solution to this…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Shuang Zeng , Lei Zhu , Xinliang Zhang , Micky C Nnamdi , Wenqi Shi , J Ben Tamo , Qian Chen , Hangzhou He , Lujia Jin , Zifeng Tian , Qiushi Ren , Zhaoheng Xie , Yanye Lu

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Detecting changes in longitudinal medical imaging using deep learning requires a substantial amount of accurately labeled data. However, labeling these images is notably more costly and time-consuming than labeling other image types, as it…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Siteng Ma , Honghui Du , Prateek Mathur , Brendan S. Kelly , Ronan P. Killeen , Aonghus Lawlor , Ruihai Dong

The practical deployment of medical vision-language models (Med-VLMs) necessitates seamless integration of textual data with diverse visual modalities, including 2D/3D images and videos, yet existing models typically employ separate…

Computation and Language · Computer Science 2025-04-22 Songtao Jiang , Yuan Wang , Sibo Song , Yan Zhang , Zijie Meng , Bohan Lei , Jian Wu , Jimeng Sun , Zuozhu Liu

Data augmentations are widely used in training medical image deep learning models to increase the diversity and size of sparse datasets. However, commonly used augmentation techniques can result in loss of clinically relevant information…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Adrit Rao , Andrea Fisher , Ken Chang , John Christopher Panagides , Katherine McNamara , Joon-Young Lee , Oliver Aalami

Multimodal image fusion aims to combine relevant information from images acquired with different sensors. In medical imaging, fused images play an essential role in both standard and automated diagnosis. In this paper, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-02-18 Farshad G. Veshki , Nora Ouzir , Sergiy A. Vorobyov , Esa Ollila

Multimodal representation learning has demonstrated remarkable potential in enabling models to process and integrate diverse data modalities, such as text and images, for improved understanding and performance. While the medical domain can…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Shuvendu Roy , Franklin Ogidi , Ali Etemad , Elham Dolatabadi , Arash Afkanpour