Related papers: Biological Pathway Guided Gene Selection Through C…

Feature selection, as a critical pre-processing step for machine learning, aims at determining representative predictors from a high-dimensional feature space dataset to improve the prediction accuracy. However, the increase in feature…

Recent advances in neural networks have inspired people to design hybrid recommendation algorithms that can incorporate both (1) user-item interaction information and (2) content information including image, audio, and text. Despite their…

Sparse regularized regression methods are now widely used in genome-wide association studies (GWAS) to address the multiple testing burden that limits discovery of potentially important predictors. Linear mixed models (LMMs) have become an…

Optimising deep neural networks is a challenging task due to complex training dynamics, high computational requirements, and long training times. To address this difficulty, we propose the framework of Generalisable Agents for Neural…

Reinforcement learning (RL) is an effective method of finding reasoning pathways in incomplete knowledge graphs (KGs). To overcome the challenges of a large action space, a self-supervised pre-training method is proposed to warm up the…

Multi-agent reinforcement learning (MARL) faces challenges in coordinating agents due to complex interdependencies within multi-agent systems. Most MARL algorithms use the simultaneous decision-making paradigm but ignore the action-level…

The analysis and control of large-population systems is of great interest to diverse areas of research and engineering, ranging from epidemiology over robotic swarms to economics and finance. An increasingly popular and effective approach…

Quantifying biomechanical properties of the human vasculature could deepen our understanding of cardiovascular diseases. Standard nonlinear regression in constitutive modeling requires considerable high-quality data and an explicit form of…

Effective governance and steering of behavior in complex multi-agent systems (MAS) are essential for managing system-wide outcomes, particularly in environments where interactions are structured by dynamic networks. In many applications,…

Coordinating large populations of interacting agents is a central challenge in multi-agent reinforcement learning (MARL), where the size of the joint state-action space scales exponentially with the number of agents. Mean-field methods…

Recent advances in large language models (LLMs) have shown great potential to accelerate drug discovery. However, the specialized nature of biochemical data often necessitates costly domain-specific fine-tuning, posing major challenges.…

Uncovering causal structures from observational data is crucial for understanding complex systems and making informed decisions. While reinforcement learning (RL) has shown promise in identifying these structures in the form of a directed…

Since the advent of autonomous driving technology, it has experienced remarkable progress over the last decade. However, most existing research still struggles to address the challenges posed by environments where multiple vehicles have to…

Structure-based drug design (SBDD) aims to discover drug candidates by finding molecules (ligands) that bind tightly to a disease-related protein (targets), which is the primary approach to computer-aided drug discovery. Recently, applying…

Recent challenges in operating power networks arise from increasing energy demands and unpredictable renewable sources like wind and solar. While reinforcement learning (RL) shows promise in managing these networks, through topological…

Many recent successful off-policy multi-agent reinforcement learning (MARL) algorithms for cooperative partially observable environments focus on finding factorized value functions, leading to convoluted network structures. Building on the…

We present a holistic data-driven approach to the problem of productivity increase on the example of a metallurgical pickling line. The proposed approach combines mathematical modeling as a base algorithm and a cooperative Multi-Agent…

Static feature exclusion strategies often fail to prevent bias when hidden dependencies influence the model predictions. To address this issue, we explore a reinforcement learning (RL) framework that integrates bias mitigation and automated…

Background: Identification of the interactions and regulatory relations between biomolecules play pivotal roles in understanding complex biological systems and the mechanisms underlying diverse biological functions. However, the collection…

In this paper, we investigate a cell-free massive multiple-input multiple-output system, which exhibits great potential in enhancing the capabilities of next-generation mobile communication networks. We first study the distributed…