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Gene panel selection aims to identify the most informative genomic biomarkers in label-free genomic datasets. Traditional approaches, which rely on domain expertise, embedded machine learning models, or heuristic-based iterative…

Genomics · Quantitative Biology 2025-09-12 Meng Xiao , Weiliang Zhang , Xiaohan Huang , Hengshu Zhu , Min Wu , Xiaoli Li , Yuanchun Zhou

Datasets with hundreds to tens of thousands features is the new norm. Feature selection constitutes a central problem in machine learning, where the aim is to derive a representative set of features from which to construct a classification…

Machine Learning · Computer Science 2016-03-17 Kleanthis Malialis , Jun Wang , Gary Brooks , George Frangou

Understanding mechanistic relationships among genes and their impacts on biological pathways is essential for elucidating disease mechanisms and advancing precision medicine. Despite the availability of extensive molecular interaction and…

Molecular Networks · Quantitative Biology 2026-03-24 Fujian Jia , Jiwen Gu , Cheng Lu , Dezhi Zhao , Mengjiang Huang , Yuanzhi Lu , Xin Liu , Kang Liu

Integrating histopathology with spatial transcriptomics (ST) provides a powerful opportunity to link tissue morphology with molecular function. Yet most existing multimodal approaches rely on a small set of highly variable genes, which…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sejuti Majumder , Saarthak Kapse , Moinak Bhattacharya , Xuan Xu , Alisa Yurovsky , Prateek Prasanna

Where causal SNPs (single nucleotide polymorphisms) tend to accumulate within biological pathways, the incorporation of prior pathways information into a statistical model is expected to increase the power to detect true associations in a…

Methodology · Statistics 2012-01-30 Matt Silver , Giovanni Montana

Recent advancements in single-cell genomics necessitate precision in gene panel selection to interpret complex biological data effectively. Those methods aim to streamline the analysis of scRNA-seq data by focusing on the most informative…

Artificial Intelligence · Computer Science 2024-06-12 Weiliang Zhang , Zhen Meng , Dongjie Wang , Min Wu , Kunpeng Liu , Yuanchun Zhou , Meng Xiao

Video Recognition has drawn great research interest and great progress has been made. A suitable frame sampling strategy can improve the accuracy and efficiency of recognition. However, mainstream solutions generally adopt hand-crafted…

Computer Vision and Pattern Recognition · Computer Science 2019-08-05 Wenhao Wu , Dongliang He , Xiao Tan , Shifeng Chen , Shilei Wen

Multi-agent reinforcement learning (MARL) has been increasingly explored to learn the cooperative policy towards maximizing a certain global reward. Many existing studies take advantage of graph neural networks (GNN) in MARL to propagate…

Machine Learning · Computer Science 2020-12-25 Wenlei Shi , Xinran Wei , Jia Zhang , Xiaoyuan Ni , Arthur Jiang , Jiang Bian , Tie-Yan Liu

Lane change decision-making is a complex task due to intricate vehicle-vehicle and vehicle-infrastructure interactions. Existing algorithms for lane-change control often depend on vehicles with a certain level of autonomy (e.g., autonomous…

Systems and Control · Electrical Eng. & Systems 2024-12-09 Ke Sun , Huan Yu

In this paper, we introduce an alternative approach to enhancing Multi-Agent Reinforcement Learning (MARL) through the integration of domain knowledge and attention-based policy mechanisms. Our methodology focuses on the incorporation of…

Machine Learning · Computer Science 2025-04-04 Andre R Kuroswiski , Annie S Wu , Angelo Passaro

This paper introduces Anticipatory Reinforcement Learning (ARL), a novel framework designed to bridge the gap between non-Markovian decision processes and classical reinforcement learning architectures, specifically under the constraint of…

Machine Learning · Computer Science 2026-04-07 Daniel Bloch

Ray tracing has become a standard for accurate radio propagation modeling, but suffers from exponential computational complexity, as the number of candidate paths scales with the number of objects raised to the interaction order. This…

Introduction It has been demonstrated that a pathway-based feature selection method which incorporates biological information within pathways into the process of feature selection usually outperform a gene-based feature selection algorithm…

Methodology · Statistics 2016-05-13 Suyan Tian , Howard H. Chang , Chi Wang

Multi-Agent Path Finding (MAPF) is a critical component of logistics and warehouse management, which focuses on planning collision-free paths for a team of robots in a known environment. Recent work introduced a novel MAPF approach, LNS2,…

Robotics · Computer Science 2025-02-03 Yutong Wang , Tanishq Duhan , Jiaoyang Li , Guillaume Sartoretti

Multi-agent reinforcement learning (MARL) provides an efficient way for simultaneously learning policies for multiple agents interacting with each other. However, in scenarios requiring complex interactions, existing algorithms can suffer…

Machine Learning · Computer Science 2022-03-08 Xiaobai Ma , David Isele , Jayesh K. Gupta , Kikuo Fujimura , Mykel J. Kochenderfer

Effective feature selection, representation and transformation are principal steps in machine learning to improve prediction accuracy, model generalization and computational efficiency. Reinforcement learning provides a new perspective…

Machine Learning · Computer Science 2025-03-18 Sumana Sanyasipura Nagaraju

Reliable identification of molecular biomarkers is essential for accurate patient stratification. While state-of-the-art machine learning approaches for sample classification continue to push boundaries in terms of performance, most of…

Molecular Networks · Quantitative Biology 2019-11-07 Matteo Manica , Joris Cadow , Roland Mathis , María Rodríguez Martínez

We propose a new framework for multi-agent reinforcement learning (MARL), where the agents cooperate in a time-evolving network with latent community structures and mixed memberships. Unlike traditional neighbor-based or fixed interaction…

Machine Learning · Computer Science 2025-05-16 Zhaoyang Shi

Significant advances have recently been achieved in Multi-Agent Reinforcement Learning (MARL) which tackles sequential decision-making problems involving multiple participants. However, MARL requires a tremendous number of samples for…

Multiagent Systems · Computer Science 2024-12-30 Xihuai Wang , Zhicheng Zhang , Weinan Zhang

Identifying measurable genetic indicators (or biomarkers) of a specific condition of a biological system is a key element of precision medicine. Indeed it allows to tailor diagnostic, prognostic and treatment choice to individual…

Machine Learning · Statistics 2016-12-16 Chloé-Agathe Azencott
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