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The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Recent methods for pathology report generation from whole-slide image (WSI) are capable of producing slide-level diagnostic descriptions but fail to ground fine-grained statements in localized visual evidence. Furthermore, they lack control…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Rundong Wang , Wei Ba , Ying Zhou , Yingtai Li , Bowen Liu , Baizhi Wang , Yuhao Wang , Zhidong Yang , Kun Zhang , Rui Yan , S. Kevin Zhou

Rapid progress in vision-language modeling has enabled pathology report generation from gigapixel whole-slide images, but most approaches assume static training with simultaneous access to all data. In clinical deployment, however, new…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Pratibha Kumari , Daniel Reisenbüchler , Afshin Bozorgpour , yousef Sadegheih , Priyankar Choudhary , Dorit Merhof

Deep image classification models trained on vast amounts of web-scraped data are susceptible to data poisoning - a mechanism for backdooring models. A small number of poisoned samples seen during training can severely undermine a model's…

Cryptography and Security · Computer Science 2023-06-30 Nils Lukas , Florian Kerschbaum

In this paper, we investigate the impact of adversarial attacks on the explainability of deep learning models, which are commonly criticized for their black-box nature despite their capacity for autonomous feature extraction. This black-box…

Machine Learning · Computer Science 2024-12-17 Gazi Nazia Nur , Mohammad Ahnaf Sadat

What fundamentally distinguishes an adversarial attack from a misclassification due to limited model expressivity or finite data? In this work, we investigate this question in the setting of high-dimensional binary classification, where…

Machine Learning · Statistics 2025-06-17 Matteo Vilucchio , Lenka Zdeborová , Bruno Loureiro

The proliferation of software vulnerabilities presents a significant challenge to cybersecurity, necessitating more effective detection methodologies. We introduce White-Basilisk, a novel approach to vulnerability detection that…

Cryptography and Security · Computer Science 2026-04-23 Ioannis Lamprou , Alexander Shevtsov , Ioannis Arapakis , Sotiris Ioannidis

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Deep Neural Network (DNN) models have vulnerabilities related to security concerns, with attackers usually employing complex hacking techniques to expose their structures. Data poisoning-enabled perturbation attacks are complex adversarial…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Mohammed Hassanin , Ibrahim Radwan , Nour Moustafa , Murat Tahtali , Neeraj Kumar

The advancement and adoption of Artificial Intelligence (AI) models across diverse domains have transformed the way we interact with technology. However, it is essential to recognize that while AI models have introduced remarkable…

Cryptography and Security · Computer Science 2025-05-07 Hema Karnam Surendrababu , Nithin Nagaraj

The efficacy of availability poisoning, a method of poisoning data by injecting imperceptible perturbations to prevent its use in model training, has been a hot subject of investigation. Previous research suggested that it was difficult to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Tianrui Qin , Xitong Gao , Juanjuan Zhao , Kejiang Ye , Cheng-Zhong Xu

Recent studies indicate that current adversarial attack methods are flawed and easy to fail when encountering some deliberately designed defense. Sometimes even a slight modification in the model details will invalidate the attack. We find…

Computer Vision and Pattern Recognition · Computer Science 2020-09-18 Chaohao Fu , Hongbin Chen , Na Ruan , Weijia Jia

Modeling and analyzing security of networked systems is an important problem in the emerging Science of Security and has been under active investigation. In this paper, we propose a new approach towards tackling the problem. Our approach is…

Cryptography and Security · Computer Science 2016-03-29 Gaofeng Da , Maochao Xu , Shouhuai Xu

Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Zijie Fang , Yifeng Wang , Ye Zhang , Zhi Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Upcoming certification actions related to the security of machine learning (ML) based systems raise major evaluation challenges that are amplified by the large-scale deployment of models in many hardware platforms. Until recently, most of…

Cryptography and Security · Computer Science 2023-09-15 Mathieu Dumont , Kevin Hector , Pierre-Alain Moellic , Jean-Max Dutertre , Simon Pontié

With the help of conditioning mechanisms, the state-of-the-art diffusion models have achieved tremendous success in guided image generation, particularly in text-to-image synthesis. To gain a better understanding of the training process and…

Cryptography and Security · Computer Science 2023-10-24 Shengfang Zhai , Yinpeng Dong , Qingni Shen , Shi Pu , Yuejian Fang , Hang Su

This work proposes a structured approach to baselining a model, identifying attack vectors, and securing the machine learning models after deployment. This method for securing each model post deployment is called the BAD (Build, Attack, and…

Cryptography and Security · Computer Science 2020-06-22 Josh Kalin , David Noever , Gerry Dozier

The use of machine learning (ML) has become increasingly prevalent in various domains, highlighting the importance of understanding and ensuring its safety. One pressing concern is the vulnerability of ML applications to model stealing…

Machine Learning · Computer Science 2026-04-07 Ganghua Wang , Yuhong Yang , Jie Ding

Survival analysis based on Whole Slide Images (WSIs) is crucial for evaluating cancer prognosis, as they offer detailed microscopic information essential for predicting patient outcomes. However, traditional WSI-based survival analysis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Zheng Wang , Hong Liu , Zheng Wang , Danyi Li , Min Cen , Baptiste Magnier , Li Liang , Liansheng Wang

In the domain of backdoor attacks, accurate labeling of injected data is essential for evading rudimentary detection mechanisms. This imperative has catalyzed the development of clean-label attacks, which are notably more elusive as they…

Cryptography and Security · Computer Science 2024-01-18 Binhao Ma , Jiahui Wang , Dejun Wang , Bo Meng
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