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Related papers: Training LLMs for EHR-Based Reasoning Tasks via Re…

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Large language models (LLMs) have demonstrated exceptional capabilities in planning and tool utilization as autonomous agents, but few have been developed for medical problem-solving. We propose EHRAgent, an LLM agent empowered with a code…

Computation and Language · Computer Science 2024-10-07 Wenqi Shi , Ran Xu , Yuchen Zhuang , Yue Yu , Jieyu Zhang , Hang Wu , Yuanda Zhu , Joyce Ho , Carl Yang , May D. Wang

Large Multimodal Models (LMMs) excel at comprehending human instructions and demonstrate remarkable results across a broad spectrum of tasks. Reinforcement Learning from Human Feedback (RLHF) and AI Feedback (RLAIF) further refine LLMs by…

Artificial Intelligence · Computer Science 2024-10-07 Ju-Seung Byun , Jiyun Chun , Jihyung Kil , Andrew Perrault

Reinforcement learning (RL) has become a key technique for enhancing the reasoning abilities of large language models (LLMs), with policy-gradient algorithms dominating the post-training stage because of their efficiency and effectiveness.…

Artificial Intelligence · Computer Science 2025-08-08 Chang Tian , Matthew B. Blaschko , Mingzhe Xing , Xiuxing Li , Yinliang Yue , Marie-Francine Moens

Structured Electronic Health Record (EHR) data stores patient information in relational tables and plays a central role in clinical decision-making. Recent advances have explored the use of large language models (LLMs) to process such data,…

Artificial Intelligence · Computer Science 2026-04-02 Xiao Yang , Xuejiao Zhao , Zhiqi Shen

Reinforcement Learning (RL) offers a powerful framework for optimizing dynamic treatment regimes (DTRs). However, clinical RL is fundamentally bottlenecked by reward engineering: the challenge of defining signals that safely and effectively…

Machine Learning · Computer Science 2026-02-05 Qianyi Xu , Gousia Habib , Feng Wu , Yanrui Du , Zhihui Chen , Swapnil Mishra , Dilruk Perera , Mengling Feng

Reinforcement learning (RL) has been widely used in training large language models (LLMs) for preventing unexpected outputs, eg reducing harmfulness and errors. However, existing RL methods mostly adopt the instance-level reward, which is…

Computation and Language · Computer Science 2024-06-18 Zhipeng Chen , Kun Zhou , Wayne Xin Zhao , Junchen Wan , Fuzheng Zhang , Di Zhang , Ji-Rong Wen

We introduce MediX-R1, an open-ended Reinforcement Learning (RL) framework for medical multimodal large language models (MLLMs) that enables clinically grounded, free-form answers beyond multiple-choice formats. MediX-R1 fine-tunes a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Sahal Shaji Mullappilly , Mohammed Irfan Kurpath , Omair Mohamed , Mohamed Zidan , Fahad Khan , Salman Khan , Rao Anwer , Hisham Cholakkal

The application of Vision-Language Models (VLMs) in medicine is critically hampered by the scarcity of high-quality, expert-annotated data. Supervised Fine-Tuning (SFT) on existing datasets often leads to poor generalization on unseen…

Machine Learning · Computer Science 2025-12-09 Weihai Zhi , Jiayan Guo , Shangyang Li

Large language models (LLMs) trained via pretraining and supervised fine-tuning (SFT) can still produce harmful and misaligned outputs, or struggle in domains like math and coding. Reinforcement learning (RL)-based post-training methods,…

Computation and Language · Computer Science 2026-05-19 Zhichao Wang , Kiran Ramnath , Bin Bi , Shiva Kumar Pentyala , Sougata Chaudhuri , Shubham Mehrotra , Zixu , Zhu , Xiang-Bo Mao , Sitaram Asur , Na , Cheng

Reinforcement learning with verifiable rewards (RLVR) has become a key technique for enhancing LLMs' reasoning abilities, yet its data inefficiency remains a major bottleneck. To address this critical yet challenging issue, we present a…

Machine Learning · Computer Science 2026-04-28 Shipeng Li , Zhiqin Yang , Shikun Li , Xiaobo Xia , Hengyu Liu , Xinghua Zhang , Gaode Chen , Dong Fang , Ying Tai , Zhe Peng

Scaling test-time computation with reinforcement learning (RL) has emerged as a reliable path to improve large language models (LLM) reasoning ability. Yet, outcome-based reward often incentivizes models to be overconfident, leading to…

Machine Learning · Computer Science 2026-04-28 Liaoyaqi Wang , Chunsheng Zuo , William Jurayj , Benjamin Van Durme , Anqi Liu

Large language models (LLMs) have emerged as promising tools for assisting in medical tasks, yet processing Electronic Health Records (EHRs) presents unique challenges due to their longitudinal nature. While LLMs' capabilities to perform…

Artificial Intelligence · Computer Science 2025-03-07 Hejie Cui , Alyssa Unell , Bowen Chen , Jason Alan Fries , Emily Alsentzer , Sanmi Koyejo , Nigam Shah

Recent advancements in large language models (LLMs) have shifted the post-training paradigm from traditional instruction tuning and human preference alignment toward reinforcement learning (RL) focused on reasoning capabilities. However,…

Artificial Intelligence · Computer Science 2025-11-12 Qianxi He , Qingyu Ren , Shanzhe Lei , Xuhong Wang , Yingchun Wang

Reward models (RMs) are essential for aligning Large Language Models (LLMs) with human preferences. However, they often struggle with capturing complex human preferences and generalizing to unseen data. To address these challenges, we…

Computation and Language · Computer Science 2025-08-06 Anamika Lochab , Ruqi Zhang

Large language models (LLMs) trained with Reinforcement Learning from Human Feedback (RLHF) have demonstrated remarkable capabilities, but their underlying reward functions and decision-making processes remain opaque. This paper introduces…

Computation and Language · Computer Science 2025-10-07 Jared Joselowitz , Ritam Majumdar , Arjun Jagota , Matthieu Bou , Nyal Patel , Satyapriya Krishna , Sonali Parbhoo

In the era of Large Language Models (LLMs), alignment has emerged as a fundamental yet challenging problem in the pursuit of more reliable, controllable, and capable machine intelligence. The recent success of reasoning models and…

Machine Learning · Computer Science 2025-07-18 Hao Sun , Mihaela van der Schaar

Recent strides in large language models (LLMs) have yielded remarkable performance, leveraging reinforcement learning from human feedback (RLHF) to significantly enhance generation and alignment capabilities. However, RLHF encounters…

Computation and Language · Computer Science 2024-05-31 Kuo Liao , Shuang Li , Meng Zhao , Liqun Liu , Mengge Xue , Zhenyu Hu , Honglin Han , Chengguo Yin

Given a question, a language model (LM) implicitly encodes a distribution over possible answers. In practice, post-training procedures for LMs often collapse this distribution onto a single dominant mode. While this is generally not a…

Machine Learning · Computer Science 2026-03-27 Isha Puri , Mehul Damani , Idan Shenfeld , Marzyeh Ghassemi , Jacob Andreas , Yoon Kim

An impediment to using Large Language Models (LLMs) for reasoning output verification is that LLMs struggle to reliably identify errors in thinking traces, particularly in long outputs, domains requiring expert knowledge, and problems…

Computation and Language · Computer Science 2026-02-09 Kate Sanders , Nathaniel Weir , Sapana Chaudhary , Kaj Bostrom , Huzefa Rangwala

Reinforcement Learning with Verifiable Rewards (RLVR) has significantly advanced the reasoning capabilities of Large Language Models (LLMs) by optimizing them against factual outcomes. However, this paradigm falters in long-context…

Computation and Language · Computer Science 2026-03-03 Guanzheng Chen , Michael Qizhe Shieh , Lidong Bing
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